Results 191 to 200 of about 244,292 (300)

Bivariate Gwas For Female And Male Fitness In Drosophila Melanogaster (Sussex, Lhm)

, 2017
William P. Gilks
openalex   +1 more source

Localizing components of shared transethnic genetic architecture of complex traits from GWAS summary data [PDF]

, 2019
Huwenbo Shi, Kathryn S. Burch, Ruth Johnson, Malika Freund, Gleb Kichaev, Nicholas Mancuso, Astrid M. Manuel, Natalie Dong, Bogdan Paşaniuc   +8 more
openalex   +1 more source

LRRK2 as a Potential Disease‐Modifying Target in Sporadic Parkinson's Disease

Movement Disorders, EarlyView.
Abstract A growing understanding of the role that leucine‐rich repeat kinase 2 (LRRK2) plays in Parkinson's disease (PD) supports continued focus on this enzyme as a therapeutic target for PD. Accumulating evidence suggests that there are phenotypic, neuropathologic, and biological similarities between sporadic PD (sPD) and familial forms in which ...
Anthony E. Lang, Robert A. Hauser, Lorraine V. Kalia, Bonnie Hersh, Zdenek Berger, Roy Llorens Arenas, Coro Paisan‐Ruiz, Kyle Fraser, Danna Jennings, Jillian H. Kluss, Sarah Huntwork‐Rodriguez, Anastasia G. Henry, J. Timothy Greenamyre   +12 more
wiley   +1 more source

Protein-protein interactions shape trans-regulatory impact of genetic variation on protein expression and complex traits. [PDF]

Nat Genet
Li J, Li YI, Liu X.
europepmc   +1 more source

Additional file 9: of GWAS for plant growth stages and yield components in spring wheat (Triticum aestivum L.) harvested in three regions of Kazakhstan

, 2017
Yerlan Turuspekov, Aida Baibulatova, Kanat Yermekbayev, Лаура Тохетова, Vladimir Chudinov, Grigoriy Sereda, Martin W. Ganal, Simon Griffiths, Сауле Абугалиева   +8 more
openalex   +1 more source

GBA1 Variants with Unknown Classification Are Modest Contributors to Parkinson's Disease Susceptibility

Movement Disorders, EarlyView.
Abstract Background GBA1 variants cause Gaucher's disease (GD) in biallelic forms and increase Parkinson's disease (PD) risk in heterozygous carriers. Carriers of mild or severe variants (causing GD type 1 or types 2–3) can enroll in clinical trials, whereas those with GBA1 variants classified as unknown are typically excluded.
Sitki Cem Parlar, Yoomin Lee, Ziv Gan‐Or   +2 more
wiley   +1 more source

The Drosophila Post-mating Response: Gene Expression and Behavioral Changes Reveal Perdurance and Variation in Cross-Tissue Interactions

G3: Genes, Genomes, Genetics, 2020
Nicole R. Newell, Surjyendu Ray, Justin E. Dalton, Julia C. Fortier, Joyce Y. Kao, Peter L. Chang, Sergey V. Nuzhdin, Michelle N. Arbeitman   +7 more
doaj   +1 more source

Brain transcriptome-wide association studies in diverse ancestral populations reveal genes implicated in an anxiety-related phenotype. [PDF]

G3 (Bethesda)
Sharma MZ, Wheeler HE.
europepmc   +1 more source

Sequencing and Imputation in GWAS: Cost-Effective Strategies to Increase Power and Genomic Coverage Across Diverse Populations [PDF]

, 2019
Corbin Quick, Pramod Anugu, Solomon K. Musani, Scott T. Weiss, Esteban G. Burchard, Marquitta J. White, Kevin L. Keys, Francesco Cucca, Carlo Sidore, Michael Boehnke, Christian Fuchsberger   +10 more
openalex   +1 more source

Impact of Alcohol Intake on Parkinson's Disease Risk and Progression: A Systematic Review and Dose–Response Meta‐Analysis of Prospective Studies

Movement Disorders, EarlyView.
Abstract The association between alcohol consumption and Parkinson's disease (PD) risk remains unclear, whereas smoking has an inverse relationship with the disease. This study systematically reviewed and meta‐analyzed 16 studies (2014–2024) from PubMed, Scopus, Web of Science, MEDLINE, and the Cochrane Library to assess the relationship between ...
Sahar Hemeda, Mohammed Elmadani, Mohammed Merzah, Aseel Odeh, Evelyn Pintér, István Balás, József Janszky, Dávid Pintér, Norbert Kovács   +8 more
wiley   +1 more source