Results 201 to 210 of about 283,327 (339)

A robust and powerful GWAS method for family trios supporting within-family Mendelian randomization analysis [PDF]

Shun Zhang, Hao-Wen Chen, J MAI, Qiu-Wen Zhu, Yue Li, Xianbo Wu, Ji‐Yuan Zhou   +6 more
openalex   +1 more source

Improving polygenic risk score based drug response prediction using transfer learning. [PDF]

NPJ Genom Med
Cheng Y, Zhai S, Zhong W, West RM, Shen J.   +4 more
europepmc   +1 more source

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen, Ningning Zhang, Ruirui Zhang, Lan Zhang, Dadong Luo, Junqiang Li, Yaqing Liu, Yunan Wang, Xinyue Duan, Xin Tian, Tiancheng Wang   +10 more
wiley   +1 more source

Using human genomics to validate drug targets for acute ischemic stroke. [PDF]

J Cereb Blood Flow Metab
Heitsch L, Lee JM.
europepmc   +1 more source

Editorial: the applications of new multi-locus GWAS methodologies in the genetic dissection of complex traits [PDF]

, 2019
Dunwell, Jim M., Jia, Zhenyu, Zhang, Yuan-Ming   +2 more
core   +2 more sources

Linkage disequilibrium score regression identifies genetic correlations between hepatocellular carcinoma and clinically relevant traits

International Journal of Cancer, EarlyView.
What's New? Hepatocellular carcinoma arises from a combination of environmental and genetic factors, with the latter playing a potentially more significant role in nonviral hepatocellular carcinoma. Here, the authors characterized the genetic correlations and heritability between nonviral hepatocellular carcinoma and 901 epidemiologic, behavioral, and ...
Younghun Han, Vikram R. Shaw, Jinyoung Byun, Aaron P. Thrift, Catherine Zhu, Donghui Li, Rikita I. Hatia, Robin Kate Kelley, Sean P. Cleary, Anna S. Lok, Paige M. Bracci, Jennifer B. Permuth, Roxana Bucur, Jennifer Knox, Jian‐Min Yuan, Amit G. Singal, Prasun K. Jalal, R. Mark Ghobrial, Yuko Kono, Dimpy P. Shah, Mindie H. Nguyen, Neehar D. Parikh, Richard Kim, Hui‐Chen Wu, Hashem El‐Serag, Ping Chang, Yun Shin Chun, Jian Gu, Chad Huff, Asif Rashid, Lu‐Yu Hwang, Alison P. Klein, Saira A. Khaderi, Ahmed O. Kaseb, Kathrine A. McGlynn, Lewis R. Roberts, Manal M. Hassan, Christopher I. Amos   +37 more
wiley   +1 more source

Harnessing genomic prediction in Brassica napus through a nested association mapping population. [PDF]

Plant Genome
Perumal S, Higgins EE, Sra S, Khedikar Y, Moore J, Chaudary R, Haile T, Koh CS, Vail S, Robinson SJ, Horner K, Hope B, Klein-Gebbinck H, Herrmann DT, Navabi K, Sharpe AG, Parkin IAP.   +16 more
europepmc   +1 more source

Supplemental Tables for "Leveraging auxiliary data from arbitrary distributions to boost GWAS discovery with Flexible cFDR" manuscript

, 2020
Anna Hutchinson
openalex   +1 more source

Sequencing and Imputation in GWAS: Cost-Effective Strategies to Increase Power and Genomic Coverage Across Diverse Populations [PDF]

, 2019
Corbin Quick, Pramod Anugu, Solomon K. Musani, Scott T. Weiss, Esteban G. Burchard, Marquitta J. White, Kevin L. Keys, Francesco Cucca, Carlo Sidore, Michael Boehnke, Christian Fuchsberger   +10 more
openalex   +1 more source

Long‐term impact of stressful life events on breast cancer risk: A 36‐year genetically informed prospective study in the Finnish Twin Cohort

International Journal of Cancer, EarlyView.
What's New? Breast cancer results from a combination of genetic and environmental causes, and the cumulative effect of stressful life events may be a contributing factor. Here, the authors analyzed data from cohort and twin‐pair studies including 36 years of follow‐up to find out how stressful life events affect breast cancer risk. They found that even
Elissar Azzi, Hannes Bode, Teemu Palviainen, Mikaela Hukkanen, Miina Ollikainen, Jaakko Kaprio   +5 more
wiley   +1 more source