Evaluation of Loss of the Y Chromosome in Peripheral Blood as a Biomarker for Prostate Cancer
ABSTRACT Background Prostate cancer (PCa) is the most common malignant tumor in men, but the widely used prostate‐specific antigen (PSA) test has limited diagnostic accuracy. Research proposes that the loss of the Y chromosome (LOY) may affect the occurrence and development of prostate cancer, aiming to assess its potential as a diagnostic biomarker to
Jun Lu +10 more
wiley +1 more source
Elucidating the susceptibility genes between insomnia and migraine by integrating genetic data and transcriptomes. [PDF]
Wang T, Li J, Yao Y, Wang H, Zheng X.
europepmc +1 more source
Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee +9 more
wiley +1 more source
A Narrative Review of the Genetic Architecture of Systemic Hypertension: From Candidate Genes to Biobank-Scale Genome-Wide Association Studies and Sequencing, With Translational Pathways to Precision Care. [PDF]
Aldhufairi A +4 more
europepmc +1 more source
miRNA contributions to pediatric‐onset multiple sclerosis inferred from GWAS [PDF]
et al,, Mar, Soe
core +1 more source
GWAS-based Machine Learning for Prediction of Age-Related Macular Degeneration Risk [PDF]
Qi Yan +7 more
openalex +1 more source
A large-scale multi-ancestry genome-wide association study of chronic prostatitis/chronic pelvic pain syndrome in men. [PDF]
Rosenthal SB +11 more
europepmc +1 more source

