Results 211 to 220 of about 283,327 (339)

Liability threshold model-based disease risk prediction based on electronic health record phenotypes. [PDF]

Nat Genet
Lee CH, Khan A, Wang C, Weng C, Buxbaum JD, Kiryluk K, Ionita-Laza I.   +6 more
europepmc   +1 more source

Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21 [PDF]

, 2018
Rubin, Joshua B.
core   +1 more source

Polygenic risk score and prostate specific antigen predict death from prostate cancer in men with intermediate aggressive cancer

International Journal of Cancer, EarlyView.
What's New? Using 21 SNPs, two novel PRS were constructed and used to develop two new machine‐learning classifiers, one for the detection of prostate cancer and the other for the prediction of its aggressiveness and subsequent mortality. The classifier for disease detection is built using the PRS as the sole feature, whereas the one for disease ...
Leandro Rodrigues Santiago, Efthymios Ladoukakis, Dorota Scibior‐Bentkowska, Belinda Nedjai   +3 more
wiley   +1 more source

Genetic correlation analysis between sepsis and hematological traits: Identifying shared genomic regions. [PDF]

PLoS One
Zhang J, Hou M, Bai Z, Wang J, Huang J.
europepmc   +1 more source

The mitochondrial DNA copy number and ovary‐related reproductive disorders: A bidirectional two‐sample Mendelian randomization study

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.
Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng, Xiao Han, Congquan Wu, Qiaowen Lu, Shujun Gao   +4 more
wiley   +1 more source

Identifying gene-environment interactions across genome-wide, twin, and polygenic risk score approaches. [PDF]

Front Genet
Verhulst B.
europepmc   +1 more source

Identification and GWAS analysis of significant genomic loci associated with mastitis resistance in Ayrshire cows

Marina V. Pozovnikova, Olga V. Tulinova, Olga K. Vasileva, Yuri S. Shcherbakov   +3 more
openalex   +1 more source

Attention Deficit Hyperactivity Disorder and other neurodevelopmental traits are associated with impact on functioning among children in the general population

JCPP Advances, EarlyView.
Abstract Background Attention Deficit Hyperactivity Disorder (ADHD) is commonly defined as a categorical diagnosis requiring clinically severe symptoms and impact on functioning. However, ADHD and other neurodevelopmental traits are also distributed continuously in the general population, where their impact on functioning is less clear.
Louise Horstmann, Charlotte A. Dennison, Evie Stergiakouli, Kate Langley, Joanna Martin   +4 more
wiley   +1 more source

Autoimmune diseases share a common genetic architecture involving the JAK-STAT pathway

EXCLI Journal : Experimental and Clinical Sciences
Iraj Saadat, Mostafa Saadat
doaj   +1 more source

Genome-wide association study identifies quantitative trait loci associated with resistance to Verticillium dahliae race 3 in tomato. [PDF]

Plant Genome
Adhikari TB, Olukolu BA, Pandey A, Philbrick AN, Panthee DR, Shekasteband R, Gardner RG, Dean RA, Louws FJ.   +8 more
europepmc   +1 more source