Results 211 to 220 of about 247,905 (333)

Defense heterosis as a novel plant protection strategy: From theory to breeding practice

New Plant Protection, EarlyView.
Defense heterosis, the enhanced disease resistance of hybrids compared to their parents, has evolved from early observations of hybrid vigor to a novel research concept. Advances are now clarifying its diverse genetic and molecular mechanisms across various plant–pathogen interactions.
Kaiqi Xu, Xue Li, Fangfang Li
wiley   +1 more source

cfGWAS reveal genetic basis of cell-free DNA end motifs. [PDF]

Nat Commun
Zhu H, Zhang Y, Li L, Zeng S, Zhang X, Lin Y, Ou R, Wang L, Li X, Wang Y, Zeng J, Lin Y, Xu C, Zeng G, Li L, Zhao R, Jia Y, Luo F, Yang M, Hu Y, Xiao H, Xu X, Wang J, Zhou A, Zhang H, Jin X.   +25 more
europepmc   +1 more source

C/EBPα is Essential for Gonadal but Not Inguinal White Adipose Tissue Formation in Mice

Obesity, EarlyView.
Human genetics has linked the gene CEBPA to waist to hip ratio and adipose distribution. We generated mice with AdipoQ‐Cre driven deletion of Cebpa and found these mice to have a specific reduction in gonadal white adipose tissue and myriad other metabolic phenotypes.
Krista Y. Hu, Yu‐Lin Ma, Esme A. Dodge, Olivia A. B. Maguire, Caio V. Matias, Ryan P. Barney, Hector S. Himede, Juliana Gomez Pardo, Miriam Cepeda, Scott M. Gordon, Robert C. Bauer   +10 more
wiley   +1 more source

Differential genome-wide association analysis of schizophrenia and post-traumatic stress disorder identifies opposing effects at the <i>MAPT</i>/<i>CRHR1</i> locus. [PDF]

Front Genet
Cheng ZS.
europepmc   +1 more source

Adipose Tissue‐Derived Small Extracellular Vesicles in Plasma Reveal Molecular Circuitries Underlying Glucose Intolerance

Obesity, EarlyView.
ABSTRACT Objective Glucose tolerance (GT) is a major effector for adipose tissue (AT) remodeling in obesity, yet its molecular mechanisms remain incompletely defined. We hypothesized that the biophysical and molecular profiles of AT‐derived small extracellular vesicles (sEVAT) change in response to glucose availability and differ by GT status.
Shalini Mishra, Yixin Su, Ashish Kumar, Sangeeta Singh, Brian S. Finlin, Fang‐Chi Hsu, Jingyun Lee, Cristina M. Furdui, Philip A. Kern, Swapan K. Das, Gagan Deep   +10 more
wiley   +1 more source

Cell type-specific network analysis in Diversity Outbred mice identifies genes potentially responsible for human bone mineral density GWAS associations. [PDF]

Elife
Dillard LJ, Calabrese G, Mesner L, Farber C.   +3 more
europepmc   +1 more source

GWAS to the people [PDF]

Nature Medicine, 2018
openaire   +2 more sources

Impact of Genetic Predisposition to Obesity on Long‐Term Maintenance of Modest Weight Loss in Postmenopausal Women

Obesity, EarlyView.
ABSTRACT Objective Long‐term weight regain limits the population‐level benefits of obesity interventions. We tested whether the polygenic risk score of BMI (PRSBMI) modifies weight trajectories following modest weight loss. Methods The analytic sample included 9897 postmenopausal women from the Women's Health Initiative Dietary Modification Trial (6132
Harold H. Lee, Christy L. Avery, Misa Graff, Daeeun Kim, Josh Arias, Linda Van Horn, Charles Kooperberg, Kari E. North   +7 more
wiley   +1 more source

Dissecting the Genetic Basis of Low Back Pain Independent of BMI Through Genomic Structural Equation Modeling. [PDF]

J Pain Res
Huo L, Tan L, Wang F, Sun J, Niu Y, Jiang Y, Wu M, Shi J, Hao Y, Wang J, Huang S, Chen Z.   +11 more
europepmc   +1 more source

bioinf-mcb/mgg_gwas: v1.0.3 – GWAS pipeline linking prophage protein clusters to Klebsiella K-loci

Janusz Koszucki
openalex   +1 more source