Results 231 to 240 of about 283,327 (339)

A review of post-GWAS studies in schizophrenia. [PDF]

open access: yesTransl Psychiatry
Maserrat S, Cairns MJ.
europepmc   +1 more source

107 GWAS identifies novel susceptibility loci for cutaneous squamous cell carcinoma [PDF]

open access: bronze, 2016
Maryam M. Asgari   +6 more
openalex   +1 more source

Integrated Roles of Systemic Diseases and Serum Biomarkers in the Incidence of Age‐Related Macular Degeneration: The UK Biobank Study

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Background To evaluate the associations of systemic diseases with AMD incidence and explore whether polygenic risk score (PRS) for AMD influences these associations. To assess the impacts of polymorbidities and serum biomarkers on AMD risk. Methods This prospective study of 471156 AMD‐free UK Biobank participants assessed systemic diseases ...
Jun Yu   +9 more
wiley   +1 more source

Potential Targets Related to Skin Aging: Based on eQTL and GWAS Datasets

open access: yesClinical, Cosmetic and Investigational Dermatology
Hanping Shi,1,2 Xianwei Cao1– 3 1School of Public Health, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330006, People’s Republic of China; 2Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Nanchang University,
Shi H, Cao X
doaj  

P4‐ATPases as Phospholipid Flippases: From Membrane Dynamics to Human Disorders

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT P4‐ATPases (P4 subfamily of P‐type ATPases) flippase complex includes an α‐subunit responsible for catalysis and a supporting β‐subunit, which consumes energy by catalyzing the hydrolysis of ATP, thereby facilitating the translocation of aminophospholipids from the outer to the inner leaflet of cellular membranes to maintain the asymmetric ...
Guangyi Chen, Yeming Yang, Xianjun Zhu
wiley   +1 more source

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

open access: yesNature Genetics, 2012
Jian Yang   +14 more
semanticscholar   +1 more source

Causal Link and Shared Biomarkers Between Rheumatoid Arthritis and Idiopathic Pulmonary Fibrosis

open access: yesMed Research, EarlyView.
ABSTRACT This study investigates the causal relationship between rheumatoid arthritis (RA) and idiopathic pulmonary fibrosis (IPF), aiming to identify shared biomarkers between the two conditions. Utilizing bidirectional Mendelian randomization (MR), we assessed causality by analyzing genome‐wide association study (GWAS) data from European cohorts ...
Xixi Pan   +5 more
wiley   +1 more source

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