Results 241 to 250 of about 247,905 (333)

Wie, was, GWAS?

InFo Hämatologie + Onkologie, 2022
openaire   +1 more source

Identification of genetically predicted protein biomarkers and drug targets for prostate cancer via Mendelian randomization

VIEW, EarlyView.
Prostate cancer, a leading cause of cancer in men globally, urgently requires improved diagnostic and treatment strategies. This study analyzed large genetic datasets and identified five key proteins (THBD, DST, IFI27L2, OSBPL10, PPP1R14A) that either increase or decrease cancer risk, while also exploring their roles in immune response and potential ...
Maoping Cai, Tianming Peng, Zhiyue Xie, Chuqian Zhen, Chen Yao, Nan Peng, Qianyi Li, Yuzhong Yu, Jiming Bao, Xian‐Lu Song, Mingkun Chen, Shan‐Chao Zhao   +11 more
wiley   +1 more source

Deep Learning for Analysis of Bone Marrow Adiposity: Breakthroughs from Recent Large-Scale Analyses in the UK Biobank. [PDF]

Curr Osteoporos Rep
Xu W, Wang C, Cawthorn WP.
europepmc   +1 more source

Detailed information on the univariate genome-wide association study (GWAS) summary statistics included in the study.

Pan Shen (5957090), Hao Xiong (86981), Qing-Hua Luo (22446487), Yi-Fan Ding (1453186), Wei Ge (39218), Wu Liao (18843741), Lei-Chang Zhang (22446490)   +6 more
openalex   +1 more source

INTRODUCTION TO GWAS

European Neuropsychopharmacology, 2021
openaire   +1 more source

Integrative Analysis of Plasma Proteome and Genome Reveals Novel Drug Targets for Chronic Rhinosinusitis and Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou, Shi Luo, Yu Xiao, Bin Liu, Xu‐Ping Xiao   +4 more
wiley   +1 more source

In-Depth characterization of the shared genetic architecture of suicide attempts with other major psychiatric disorders. [PDF]

Transl Psychiatry
Kim MJ, Gunn S, Wang D, Shiau F, Lazcano P, Mann JJ, Singh TJ.   +6 more
europepmc   +1 more source

miRNA contributions to pediatric‐onset multiple sclerosis inferred from GWAS [PDF]

, 2019
et al,, Mar, Soe
core   +1 more source

Estimating Trait Heritability from GWAS Data

, 2011
Stephen Turner
openalex   +1 more source

Sex Hormones and the Risk of Nasal Polyps: A Two‐Sample Mendelian Randomization Study

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective The pathophysiological roles of sex hormones in airway inflammation have drawn much attention recently. We aimed to explore the causal effect of sex hormones on chronic rhinosinusitis (CRS) and nasal polyps (NP) via a Mendelian randomization (MR) study.
Ying Zhu, Jia‐Yao Zhou, Shi‐Yao Zhang, Ru Tang, Chun‐Yu Luo, Yue‐Long Gu, Zhi‐Peng Li, Wei‐Tian Zhang   +7 more
wiley   +1 more source