Increased genomic predictive ability in mango using GWAS-preselected variants and fixed-effect SNPs. [PDF]
Munyengwa N +8 more
europepmc +1 more source
CXCR4 involvement in neurodegenerative diseases [PDF]
Karch, Celeste M., Wen, Natalie
core +1 more source
This graphical abstract illustrates the cloud‐based GWAS platform as a hub that integrates six major multiomics domains: phenomics, neuroscience, proteomics, microbiomics, metabolomics, and nutrigenomics. The platform unifies diverse data types—including clinical phenotypes, neuroimaging, plasma proteomics, microbiome profiles, metabolic biomarkers ...
Xiaohong Ke +12 more
wiley +1 more source
Cross-tissue transcriptome-wide association studies identify genetic susceptibility genes for prostate cancer. [PDF]
Hua J +8 more
europepmc +1 more source
Genome-wide analysis of self-reported risk-taking behaviour and cross-disorder genetic correlations in the UK Biobank cohort [PDF]
Bierut, Laura +3 more
core +1 more source
Characterization of the full site frequency spectrum of GWAS risk alleles in psychiatric disorders
Dmytro Pravdyvets
openalex +1 more source
MendelR: A One‐Stop R Toolkit for Mendelian Randomization Analysis
ABSTRACT MendelR is a fully automated R package specifically developed for Mendelian randomization (MR) studies, designed to address the technical challenges of causal inference in biomedical research. As a powerful causal inference method, Mendelian randomization can effectively reduce confounding bias in observational studies.
Xiaohong Ke +4 more
wiley +1 more source
Genetic underpinnings and causal effects of brain structure and function on chronic pain intensity. [PDF]
Wang X +12 more
europepmc +1 more source
Does COMT Play a Role in Parkinson's Disease Susceptibility across Diverse Ancestral Populations?
Abstract Background The catechol‐O‐methyltransferase (COMT) gene is involved in brain catecholamine metabolism, but its association with Parkinson's disease (PD) risk remains unclear. Objective Our aim was to investigate the relationship between COMT genetic variants and PD risk across diverse ancestries.
Miguel Martín‐Bórnez +16 more
wiley +1 more source

