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Fluoroquinolone interactions with Mycobacterium tuberculosis gyrase: Enhancing drug activity against wild-type and resistant gyrase [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2016 Mycobacterium tuberculosis is a significant source of global morbidity and mortality. Moxifloxacin and other fluoroquinolones are important therapeutic agents for the treatment of tuberculosis, particularly multidrug-resistant infections.
Robert J Kerns +2 more
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DNA Gyrase: Structure and Function
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Exploiting bacterial DNA gyrase as a drug target: current state and perspectives
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DNA gyrase inhibitors: Progress and synthesis of potent compounds as antibacterial agents
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