A cortical shape-adaptive approach to local gyrification index. [PDF]
Med Image Anal, 2018 The amount of cortical folding, or gyrification, is typically measured within local cortical regions covered by an equidistant geodesic or nearest neighborhood-ring kernel. However, without careful design, such a kernel can easily cover multiple sulcal and gyral regions that may not be functionally related. Furthermore, this can result in smoothing out
Lyu I +4 more
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Local gyrification index in probands with psychotic disorders and their first-degree relatives. [PDF]
Biol Psychiatry, 2014 Psychotic disorders are characterized by aberrant neural connectivity. Alterations in gyrification, the pattern and degree of cortical folding, may be related to the early development of connectivity. Past gyrification studies have relatively small sample sizes, yield mixed results for schizophrenia, and are scant for psychotic bipolar and ...
Nanda P +9 more
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Prefrontal Cortex Gyrification Index in Twins: An MRI Study [PDF]
European Archives of Psychiatry and Clinical Neuroscience, 2011 Cortical development and folding seems to be under environmental as well as genetic control. The aim of our study was to estimate the genetic influence on gyrification and cortical volumes, comparing prefrontal gyrification index (GI) in monozygotic (MZ) and dizygotic (DZ) twin pairs, and unrelated pairs. Twenty-four subjects (6 pairs of MZ and 6 pairs
Thomas Schneider-Axmann +2 more
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Analysis of local gyrification index using a novel shape-adaptive kernel and the standard FreeSurfer spherical kernel – evidence from chronic schizophrenia outpatients [PDF]
Heliyon, 2020 Schizophrenia can be considered a brain disconnectivity condition related to aberrant neurodevelopment that causes alterations in the brain structure, including gyrification of the cortex.
Olga Płonka +2 more
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Local gyrification index and sulcal depth as imaging markers of cognitive decline in Alzheimer's disease. [PDF]
Front Aging NeurosciPurposeTo investigate the correlation between cortical thickness (CT), sulcal depth (SD), local gyrification index (LGI), and cognitive scores in patients with Alzheimer’s disease (AD).MethodsA total of 200 patients with AD from 2014 to 2021 were included, confirmed by 18F-florbetaben-positron emission tomography, and having a Clinical Dementia Rating ...
Sim Y +5 more
europepmc +5 more sources
A Longitudinal Study of Local Gyrification Index in Young Boys With Autism Spectrum Disorder. [PDF]
Cereb Cortex, 2019 Local gyrification index (LGI), a metric quantifying cortical folding, was evaluated in 105 boys with autism spectrum disorder (ASD) and 49 typically developing (TD) boys at 3 and 5 years-of-age. At 3 years-of-age, boys with ASD had reduced gyrification in the fusiform gyrus compared with TD boys.
Libero LE +4 more
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Altered Local Gyrification Index and Corresponding Functional Connectivity in Medication Free Major Depressive Disorder. [PDF]
Front Psychiatry, 2020 A lot of previous studies have documented that major depressive disorder (MDD) is a developmental disorder. The cortical surface measure, local gyrification index (LGI), can well reflect the fetal and early postnatal neurodevelopmental processes. Thus, LGI may provide new insight for the neuropathology of MDD.
Long J +6 more
europepmc +5 more sources
Brain Gyrification Index in Schizophrenia (Review, Systematic Review and Meta-Analysis)
Procedia Computer Science, 2021 Abstract This review examines the hypothesis that one of the links in the pathogenesis of schizophrenia may be a violation of the folding mechanism of the convolutions and furrows of the brain in the prenatal period with a change in the index of gyrification and thickness of the cortex in certain brain areas.
N V Zakharova, V L Ushakov
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Bidirectional cortical gyrification alterations in chronic obstructive pulmonary disease: links to cognitive impairment and global initiative for chronic obstructive lung disease staging [PDF]
BMC Medical ImagingPurpose Cognitive impairment is a common but poorly understood comorbidity in chronic obstructive pulmonary disease (COPD). Although gray matter abnormalities have been observed in this population, the contribution of cortical gyrification—a structural ...
Jiajie Chen +9 more
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Fetal brain volumes and brain gyrification index associated with opioid exposure. [PDF]
Brain CommunAbstract Opioid use during pregnancy continues to be a significant public health challenge, with antenatal opioid exposure suggesting adverse infant and child health outcomes. Early identification of risk of future neurodevelopmental disorders could help improve long-term health outcomes in these children.
Vishnubhotla RV +8 more
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