Results 21 to 30 of about 33,619 (164)

Resolution therapy: Harnessing efferocytic macrophages to trigger the resolution of inflammation

Frontiers in Immunology, 2022
Several chronic inflammatory diseases are associated with non-resolving inflammation. Conventional anti-inflammatory drugs fail to completely cure these diseases.
Philippe Saas, Mathieu Vetter, Melissa Maraux, Francis Bonnefoy, Francis Bonnefoy, Sylvain Perruche, Sylvain Perruche   +6 more
doaj   +1 more source

The ATG8 Family Proteins GABARAP and GABARAPL1 Target Antigen to Dendritic Cells to Prime CD4⁺ and CD8⁺ T Cells

Cells, 2022
Vaccine therapy is a promising method of research to promote T cell immune response and to develop novel antitumor immunotherapy protocols. Accumulating evidence has shown that autophagy is involved in antigen processing and presentation to T cells.
Leïla Fonderflick, Timothée Baudu, Olivier Adotévi, Michaël Guittaut, Pascale Adami, Régis Delage-Mourroux   +5 more
doaj   +1 more source

PD-L1 expression is regulated by both DNA methylation and NF-kB during EMT signaling in non-small cell lung carcinoma

OncoImmunology, 2018
Tumor cells, which undergo Epithelial-mesenchymal transition (EMT) acquire increased capacities of proliferation, invasion and have the ability to generate metastases by escaping the immune system during their systemic migration.
A. Asgarova, K. Asgarov, Y. Godet, P. Peixoto, A. Nadaradjane, M. Boyer-Guittaut, J. Galaine, D. Guenat, V. Mougey, J. Perrard, J. R. Pallandre, A. Bouard, J. Balland, C. Tirole, O. Adotevi, E. Hendrick, M. Herfs, P. F. Cartron, C. Borg, E. Hervouet   +19 more
doaj   +1 more source

BPDCN: When polychemotherapy does not compromise allogeneic CD123 CAR‐T cell cytotoxicity

eJHaem, 2021
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematological malignancy with poor prognosis and no treatment consensus. Combining chemotherapy and immunotherapy is a promising strategy to enhance therapeutic effect. Before combining these
Margaux Poussard, Laure Philippe, Maxime Fredon, Elodie Bôle‐Richard, Sabeha Biichle, Florian Renosi, Sophie Perrin, Marie Kroemer, Samuel Limat, Francis Bonnefoy, Etienne Daguindau, Eric Deconinck, Bérengère Gruson, Philippe Saas, Olivier Adotévi, Francine Garnache‐Ottou, Fanny Angelot‐Delettre   +16 more
doaj   +1 more source

Immunological memory to blood-stage malaria infection is controlled by the histamine releasing factor (HRF) of the parasite

Scientific Reports, 2017
While most subunit malaria vaccines provide only limited efficacy, pre-erythrocytic and erythrocytic genetically attenuated parasites (GAP) have been shown to confer complete sterilizing immunity.
Claudia Demarta-Gatsi, Roger Peronet, Leanna Smith, Sabine Thiberge, Robert Ménard, Salaheddine Mécheri   +5 more
doaj   +1 more source

Photooxidation of 18‐Carbon Polyunsaturated Fatty Acids to Prepare Mono‐Hydroxylated Octadecanoids

Lipids, EarlyView.
We developed a fast and simple one‐step synthetic strategy to produce mono‐hydroxylated metabolites based on the photosensitized oxidation of 18‐carbon polyunsaturated fatty acids (PUFAs). This approach could likely be extended to other PUFAs, suggesting that photosensitized oxidation could be employed to rapidly prepare hydroperoxides from multiple ...
Johanna Revol‐Cavalier, Mats Hamberg, Craig E. Wheelock   +2 more
wiley   +1 more source

The NMD Pathway Regulates GABARAPL1 mRNA during the EMT

Biomedicines, 2021
EMT is a reversible cellular process that is linked to gene expression reprogramming, which allows for epithelial cells to undergo a phenotypic switch to acquire mesenchymal properties.
Timothée Baudu, Chloé Parratte, Valérie Perez, Marie Ancion, Stefania Millevoi, Eric Hervouet, Anne Peigney, Paul Peixoto, Alexis Overs, Michael Herfs, Annick Fraichard, Michaël Guittaut, Aurélie Baguet   +12 more
doaj   +1 more source

In vitro effects of three woody plant and sainfoin extracts on two parasitic stage of 3 parasitic nematode species [PDF]

, 2004
Most studies on the effects of tanniferous plants on nematodes have examined forages but have neglected the woody plants. Therefore, in vitro effects of extracts from 3 woody plants (Rubus fructicosus, Quercus robur, Corylus avellana) have been tested on
H., HOSTE, I., FOURASTE, V., PAOLINI
core  

Haunting the Historiography of Slaves in South Asia from the nineteenth century to the present

Gender &History, EarlyView.
ABSTRACT Using both English and Urdu‐language records, this article traces the career of a few African and Afro‐Asian women slaves in the household‐state of Awadh during the first half of the nineteenth century. Focusing on the same records, this article compares a master‐poet's recognition of the motherhood of the African and Afro‐Asian slaves to the ...
Indrani Chatterjee
wiley   +1 more source

GABARAPL1 Inhibits EMT Signaling through SMAD-Tageted Negative Feedback

Biology, 2021
The pathway of selective autophagy, leading to a targeted elimination of specific intracellular components, is mediated by the ATG8 proteins, and has been previously suggested to be involved in the regulation of the Epithelial–mesenchymal transition (EMT)
Marine Jacquet, Eric Hervouet, Timothée Baudu, Michaël Herfs, Chloé Parratte, Jean-Paul Feugeas, Valérie Perez, Célia Reynders, Marie Ancion, Marc Vigneron, Aurélie Baguet, Michaël Guittaut, Annick Fraichard, Gilles Despouy   +13 more
doaj   +1 more source