Results 151 to 160 of about 468,648 (266)

Whole-protein screening and multi-modal profiling of antigen-specific CD4⁺ T cells at single-cell resolution. [PDF]

Nat Commun
Zhang R, Qi J, McKasson M, Choi J, Gutierrez V, Brennan C, Hong S, Chour W, Ng RH, Xie J, Yuan D, Webster A, Sidhu SK, Anderson A, Chen D, Edmark R, Murray KM, Li S, McDonald C, Rowen L, Wang S, Rasheed Y, Su Y, Wagner JR, Chen JM, Nawaly K, Fu J, Duven A, Forman SJ, Song M, Priceman SJ, Brown CE, Ribas A, Wong DJ, Paulson KG, Drescher CW, Puig-Saus C, Goldman JD, Trimble CL, Heath JR.   +39 more
europepmc   +1 more source

Portable Molecularly Imprinted Polymer Sensor for Rapid Swab‐Based Detection of Norovirus

Advanced Healthcare Materials, EarlyView.
This work reports a rapid, portable smartphone‐based sensor capable of detecting four norovirus genotypes from swab samples within 15 min. Sensor selectivity was validated through evaluation against four common live viruses. The swab‐based sampling process enabled simple sample preparation combined with the compact detection system, supporting use of ...
Amy Dann, Pankaj Singla, Minji Kim, Sloane Stoufer, Clare Thomas, Robert D. Crapnell, Craig E. Banks, Jake McClements, Shayan Seyedin, Mark Geoghegan, Samuel T. Jones, Christopher F. Blanford, Matthew D. Moore, Marloes Peeters   +13 more
wiley   +1 more source

Teleost intestinal microfold cells: identification, characterization, and mucosal antigen sampling in olive flounder (<i>Paralichthys olivaceus</i>). [PDF]

Mar Life Sci Technol
Sun J, Song M, Sheng X, Feng Y, Tang X, Xing J, Chi H, Zhan W.   +7 more
europepmc   +1 more source

Encoded Cell‐Material Interactions to Reroute Cytokine Signaling for Regenerative Medicine

Advanced Healthcare Materials, EarlyView.
We present native MATRIX (Material Activated To Regulate Inducible gene eXpression), a co‐engineered material‐cell platform. Surfaces functionalized with antibodies for endogenous soluble ligands (e.g., IL‐1β or IL‐6) capture and immobilize ligands for presentation to a cognate, engineered synthetic Notch receptor, releasing a transcription factor (TF)
Zachary M. Eidman, Jhanvi Sharma, Joanne C. Lee, Nicholas F. Schulze, Hannah J. Brien, Kevin C. Corn, Marjan Rafat, Jonathan M. Brunger   +7 more
wiley   +1 more source

A single polypeptide vaccine derived from multiple antigens confers protection against staphylococcus aureus infection in mice. [PDF]

Trop Dis Travel Med Vaccines
Chan CH, Dou Y, Li R, Zhang BZ, Wang X, Huang JD.   +5 more
europepmc   +1 more source

Nanomaterial Strategies for Pulmonary Delivery of Immunotherapeutics in Lung Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Inhalable immunotherapeutic nanomedicines enable organ‐selective immune modulation by overcoming pulmonary delivery barriers and concentrating therapy within lung tumors. This Review defines how nanomaterial properties govern airway deposition, retention, cellular partitioning, and immune activation across vaccines, checkpoint blockade, STING agonists,
Han Zhang, Wei Tang
wiley   +1 more source

Molecular Mimicry Between Epstein-Barr Virus and Human Herpesvirus-6 Proteins and Central Nervous System Proteins: Implications for T and B Cell Immunogenicity in an In Silico Study. [PDF]

Immun Inflamm Dis
Almulla AF, Normatov MG, Supasitthumrong T, Maes M.   +3 more
europepmc   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Optimization of a Target Antigen Diagnostic Pathway for Membranous Nephropathy. [PDF]

Kidney Int Rep
Li W, Huang C, Yue S, Rao Q, Qin X, Hu H, Wang L, Cen J, Xu R, Song H, Xu Y, Zhang X, Wang X, Dong X, Cheng Y, Wan Q.   +15 more
europepmc   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source