Results 31 to 40 of about 511,561 (316)
Non-H-2 antigens on fibroblasts and an embryocarcinoma cell line react with xenoantisera against H-2 antigens. [PDF]
Proceedings of the National Academy of Sciences, 1979 The murine embryocarcinoma cell line F9 lacks the classical transplantation antigens. However, rabbit anti-H-2 antigen sera, recognizing "backbone structures" of H-2 K and D antigens, react with three types of molecules manufactured by F9 cells. A 49,000- and a 25,000-dalton chain are glycoproteins located on the cell surface.
Kvist, S, Ostberg, L, Peterson, P A
openaire +2 more sources
Exploring the immunology of parasitism--from surface antigens to the hygiene hypothesis [PDF]
, 2009 Helminth immunology is a field which has changed beyond recognition in the past 30 years, transformed not only by new technologies from cDNA cloning to flow cytometry, but also conceptually as our definition of host immune pathways has matured.
R. M. MAIZELS, Maizels, R M
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke +4 more
wiley +1 more source
Modification of H-2 Antigenic Sites by Enzymatic Treatment Influences Virus-Specific Target Cell Lysis [PDF]
, 1976 Vaccinia virus-infected cells were treated enzymatically to remove H-2 antigenic sites. The effect of this procedure on virus-specific cell-mediated cytolysis (CMC) and virus-specific antibody-mediated cytolysis (AMC) was tested. Due to the inhibition of
Ertl, H C +3 more
core
Sequence of the mouse Q4 class I gene and characterization of the gene product [PDF]
, 1988 The Q4 class I gene has been shown to participate in gene conversion events within the mouse major histocompatibility complex. Its complete genomic nucleotide sequence has been determined.
Robinson, Peter J. +3 more
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Metabolism Open, 2020 Background: Post-translational modification (PTM) of antigens plays a role in the pathogenesis of many autoimmune disorders. In coeliac disease (CD), tissue transglutaminase (tTG) deamidates gliadin peptides to activate the immune response against the ...
Catherine Donnelly, Alistair Williams
doaj +1 more source
Structure and biosynthesis of histocompatibility antigens (H-2, HLA) [PDF]
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1982 Abstract Histocompatibility antigens (H-2K, D and L, and HLA-A, B and C) are highly polymorphic cell surface proteins. Their primary structure has been determined by sequencing the protein, complementary DNAs (cDNAs) or genes in several laboratories.
Dobberstein, B. +2 more
openaire +3 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Evaluation of Different Antigens in Western Blotting Technique for the Diagnosis of Sheep Haemonchosis [PDF]
Iranian Journal of Parasitology, 2007 Background: To use different methods for serodiagnosis of ruminants' haemonchosis is important because detection of egg in the faeces is not so reliable. Methods: Peptide bands of 5 different crude antigens of intestine, uterus, cuticle, whole male and
B Meshgi +1 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source