O presente trabalho teve como objetivo a produção de exoantígenos H e M das amostras 58, B-679, A-811 e O187 de Histoplasma capsulatum, utilizando o meio NGTA (neopeptona, glicose, tiamina e asparagina) em períodos de cultivo de 1, 2 e 3 meses, a 36ºC ...
Nilma Maciel Garcia +3 more
doaj +1 more source
Buffering Adaptive Immunity by Hydrogen Sulfide
T cell-mediated adaptive immunity is designed to respond to non-self antigens and pathogens through the activation and proliferation of various T cell populations. T helper 1 (Th1), Th2, Th17 and Treg cells finely orchestrate cellular responses through a
Giulia Pozzi +7 more
doaj +1 more source
Gr1+IL-4-producing innate cells are induced in response to Th2 stimuli and suppress Th1-dependent antibody responses [PDF]
Alum is used as a vaccine adjuvant and induces T<sub>h</sub>2 responses and T<sub>h</sub>2-driven antibody isotype production against co-injected antigens.
A. S. McKee +45 more
core +1 more source
Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition [PDF]
We developed a method for production of antigen-specific, H-2-restricted T cell hybrids. The tumor cell partner in the fusions was itself a T cell hybrid, FS6-14.13.AG2 (or its derivatives), which could be induced to produce the growth factor, interleukin-2 (IL-2), in response to a challenge with concanavalin A, but had no known antigen specificity ...
J W, Kappler +3 more
openaire +2 more sources
Preparation of alginate coated chitosan microparticles for vaccine delivery
Background Absorption of antigens onto chitosan microparticles via electrostatic interaction is a common and relatively mild process suitable for mucosal vaccine.
Wei YuQuan +6 more
doaj +1 more source
Involvement of Mhc Loci in immune responses that are not Ir-gene-controlled [PDF]
Twenty-nine randomly chosen, soluble antigens, many of them highly complex, were used to immunize mice of two strains, C3H and B10.RIII. Lymphnode cells from the immunized mice were restimulated in vitro with the priming antigens and the proliferative ...
C. J. Kreo +28 more
core +1 more source
H-2 antigens on nuclear membranes.
W. H. W. Albert, D. A. L. Davies
openalex +2 more sources
Integration of a virus membrane protein into the lipid bilayer of target cells as a prerequisite for immune cytolysis [PDF]
Structural requirements for membrane antigens on target cells to mediate immune cytolysis were studied in a model system with purified membrane proteins from Semliki Forest virus (SFV). These SFV spike proteins were isolated in the form of detergent- and
Barz, D. +3 more
core +1 more source
Stabilizing short-lived Schiff base derivatives of 5-aminouracils that activate mucosal-associated invariant T cells [PDF]
Mucosal-associated invariant T (MAIT) cells are activated by unstable antigens formed by reactions of 5-amino-6-D-ribitylaminouracil (a vitamin B2 biosynthetic intermediate) with glycolysis metabolites such as methylglyoxal.
Chen, Zhenjun +10 more
core +4 more sources
Lack of class I H-2 antigens in cells transformed by radiation leukemia virus is associated with methylation and rearrangement of H-2 DNA [PDF]
Transformation of murine thymocytes by radiation leukemia virus is associated with reduced expression of the class I antigens encoded in the major histocompatibility complex (MHC) and increased methylation and altered restriction enzyme patterns of MHC ...
Boral, Anthony +11 more
core +1 more source

