Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Selective Harmonic Mitigation Technique for Cascaded H-Bridge Converters With Nonequal DC Link Voltages [PDF]
, 2013 Multilevel converters have received increased interest recently as a result of their ability to generate high quality output waveforms with a low switching frequency. This makes them very attractive for high power applications.
Aguirre Echanove, Miguel Ángel +5 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Hardware design of magnetically isolated gate driver using insulated gate bipolar transistor (IGBT) [PDF]
, 2017 This paper presents the hardware design of compact H-bridge magnetically isolated gate driver using Insulated Gate Bipolar Transistor (IGBT) as power device.
Abdul Harris, Faranadia +4 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
DC-link voltage balancing in cascaded H-Bridge converters
Archives of Electrical Engineering, 2014 In this paper a DC-link voltage balancing strategy for multilevel Cascaded H-Bridge (CHB) converter is proposed. Presented solution bases on optimal choice of active vector durations in Space-Vector Pulse Width Modulation (SV-PWM).
Lewicki Arkadiusz
doaj +1 more source
DC-Voltage-Ratio Control Strategy for Multilevel Cascaded Converters Fed With a Single DC Source [PDF]
, 2009 Recently, a multilevel cascaded converter fed with a single DC source has been presented. An analysis of the steady-state working limits of this type of converter is presented in this paper.
Carrasco Solís, Juan Manuel +4 more
core
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
A Simple Analysis of the Second (Extra) Disulfide Bridge of VHHs
MoleculesCamelids produce a special type of antibody, known as VHHs, that has lost the VL domain, providing a more optimised VH domain. This particular highly stable antibody domain has interesting properties for biotechnological development.
Carla Martins +4 more
doaj +1 more source
Improved harmonic performance of cascaded H-Bridge converters with thermal control [PDF]
, 2018 Among multilevel converter topologies, the cascaded H-bridge converter (CHB) is one suitable solution for multiple applications such as flexible ac transmission systems and motor drives.
Buticchi, Giampaolo +5 more
core +1 more source