Results 11 to 20 of about 47,678 (217)
ESCIN MITIGATES HYPOXIA MIMICKING NCI-H23 CELLS THROUGH MODULATION OF MMPs, HIF-1α AND HIF-2α
International Journal of Pharmacy and Pharmaceutical Sciences, 2020 Objective: The objective of the study is to investigate the effect of escin in hypoxia mimicked NCI-H23 cells through the modulation of matrix metalloproteinases (MMPs) 2 and 9. Methods: In escin-treated NCI-H23 cells, adhesion, migration, and invasion were detected by the adhesion, wound healing, and Boyden chamber assays, respectively.
PANNEER SELVAM CHERMAKANI +1 more
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Molecular Medicine Reports, 2014 Radiotherapy has been used to treat cancer for >100 years and is required by numerous patients with cancer. Ionizing radiation effectively inhibits the growth of cancer cells by inducing cell death and increasing anticancer immunity, through the induction of natural killer group 2 member D ligands (NKG2DLs); however, adverse effects have also been ...
Woong, Heo +5 more
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Cytotoxic Activities of Physalis minima L. Chloroform Extract on Human Lung Adenocarcinoma NCI‐H23 Cell Lines by Induction of Apoptosis [PDF]
Evidence-Based Complementary and Alternative Medicine, 2011 Physalis minima L. is reputed for having anticancer property. In this study, the chloroform extract of this plant exhibited remarkable cytotoxic activities on NCI‐H23 (human lung adenocarcinoma) cell line at dose‐ and time‐dependent manners (after 24, 48 and 72 h of incubation).
Ooi Kheng Leong +2 more
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Oncology Letters, 2017 Two-drug combination chemotherapy, often including cisplatin and one other drug, remains the standard of care for patients with advanced non-small cell lung cancer (NSCLC). To improve the treatment of late-stage NSCLC and decrease the toxicity of combination chemotherapy, the search for novel drugs remains vigorous. Ent-11α-hydroxy-15-oxo-kaur-16-en-19-
Li, Yuchan +5 more
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Activation of a nonexpressed hypoxanthine phosphoribosyltransferase allele in mutant H23 HeLa cells by agents that inhibit DNA methylation. [PDF]
Molecular and Cellular Biology, 1986 HeLA H23 cells are a mutant female human tumor cell line harboring defective hypoxanthine phosphoribosyltransferase (HPRT; IMP-pyrophosphate phosphoribosyltransferase, EC 2.4.2.8) as a result of a mutation that alters the isoelectric point of the enzyme (G. Milman, E. Lee, G. S. Changas, J. R. McLaughlin, and J. George, Jr., Proc. Natl. Acad. Sci.
R, Ivarie, J A, Morris
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Expression of genes coding for pS2, c‐erbB2, estrogen receptor and the H23 breast tumor‐associated antigen [PDF]
FEBS Letters, 1990 Expression of the gene coding for a new breast tumor‐associated antigen, H23, was compared to expression of genes coding for pS2, c‐erbB2 and estrogen receptor (ER). Comparison involved mRNA expression in normal and malignant breast tissues as well as in non‐breast tumors.
Zaretsky, Joseph Z. +5 more
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KRAS G12C as a Target of Naringenin for Inducing Cell Death in NCI-H23 Cells
Pharmacognosy Research, 2022 Background: Naringenin (NGN) is a commonly available flavonoid in the citrus fruits. We have previously shown that NGN is cytotoxic to the non-small cell lung cancer (NSCLC) cell line NCI-H23 (H23).
Abani Kumar Patar +4 more
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Journal of Biomolecular Structure and Dynamics, 2023 The tumour suppressor protein PTEN is often down-regulated in non-small cell lung cancer. A major protein promoting the lowering of the PTEN protein is WWP2. Polyphenols have been shown to promote the expression of tumour suppressor genes like PTEN.
Sapna M. Borah +6 more
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Egyptian Academic Journal of Biological Sciences C Physiology and Molecular Biology, 2021 mushroom ) has been for a as a folk for multiple diseases in several parts of the world without rendering any undesired toxicity. In this study, I. obliquus polysaccharides (IOP) were extracted and assessed to determine their anti-tumorigenic potential ...
M. Al-Tuwaijri +5 more
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