Results 71 to 80 of about 9,362 (182)

Autophagy induction regulates influenza virus replication in a time-dependent manner [PDF]

, 2017
Autophagy plays a key role in host defence responses against microbial infections by promoting degradation of pathogens and participating in acquired immunity.
Abdoli, Asghar, Bamdad, Taravat, Feizi, Amir, Feizi, Neda, Fotouhi, Fatemeh, Jamali, Abbas, Mehrbod, Parvaneh, Nasrollahi Nargesabad, Reza, Ollah Jazaeri, Ehsan, Romani, Bizhan, Saleh, Maryam, Shokouhi Targhi, Hadiseh, Soleimanjahi, Hoorieh   +12 more
core   +1 more source

Attenuation of Influenza a Virus into Live Vaccines Through C‐End Degrons

Advanced Science, Volume 13, Issue 19, 2 April 2026.
Naturally occurring C‐end degrons are exploited to design proteolysis‐targeting live attenuated influenza vaccines. C‐end degron tagging of viral M1 protein promotes proteasome‐dependent degradation, resulting in robust attenuation in host cells while permitting scalable production in engineered cells.
Ping Wang, Le Li, Yunfang Chen, Le Tong, Zhen Li, Rong Yu, Quan Shen, Qikai Wang, Jihuan Hou, Qisi Zhang, Xu Si, Ning Wang, Demin Zhou, Wen‐xia Tian, Longlong Si   +14 more
wiley   +1 more source

Comparative Analysis of Whole-Transcriptome RNA Expression in MDCK Cells Infected With the H3N2 and H5N1 Canine Influenza Viruses

Frontiers in Cellular and Infection Microbiology, 2019
This study aimed to detect changes in the complete transcriptome of MDCK cells after infection with the H5N1 and H3N2 canine influenza viruses using high-throughput sequencing, search for differentially expressed RNAs in the transcriptome of MDCK cells ...
Pan Tao, Pan Tao, Pan Tao, Zhangyong Ning, Xiangqi Hao, Xiangqi Hao, Xiangqi Hao, Xi Lin, Xi Lin, Xi Lin, Qingxu Zheng, Qingxu Zheng, Qingxu Zheng, Shoujun Li, Shoujun Li, Shoujun Li   +15 more
doaj   +1 more source

Antigen specificity, not tissue compartment, determines clonal sharing among respiratory tract CD8+ resident memory T cells

Immunology &Cell Biology, Volume 104, Issue 4, Page 358-367, April 2026.
Abstract Tissue‐resident memory (Trm) CD8+ T cells in the upper and lower respiratory tract play an instrumental role in combatting influenza virus. While CD8+ Trm populations in these compartments differ in longevity and developmental requirements, it remains unclear whether they share clonotypes, indicating a common origin, or are seeded by distinct ...
Thi H O Nguyen, Hayley A McQuilten, Angela Pizzolla, Sneha Sant, Kim L Harland, Jessica Braverman, Katherine Kedzierska, Linda M Wakim   +7 more
wiley   +1 more source

An outbreak of influenza A(H3N2) in Alappuzha district, Kerala, India, in 2011

Journal of Infection in Developing Countries, 2015
Introduction: Influenza is an RNA virus that belongs to the Orthomyxoviridae family. It causes a highly contagious acute respiratory illness, has been recognized since ancient times, and is a major health threat throughout the world.
Sam Peter, Anukumar Balakrishnan, Varsha A Potdar, Mandeep S Chadha, Santhosh M Jadhav   +4 more
doaj   +1 more source

Postinfection Pig and Ferret Antisera Show Similar Antigenic Profiles for Human Influenza A(H1N1pdm09) Viruses

Influenza and Other Respiratory Viruses, Volume 20, Issue 4, April 2026.
ABSTRACT Background Monitoring antigenic drift in human influenza A viruses is essential for vaccine strain selection and ensuring protection against circulating strains. Antigenic drift is traditionally assessed using ferret antisera, which provide monospecific responses and human vaccinee sera, which reflect exposure to multiple antigens.
Ruth Harvey, Tiphaine Cayol, Basudev Paudyal, Alice Lilley, Christine Carr, Catherine Hatton, Emily Briggs, Rodney S. Daniels, Samuel Richardson, Thomas P. Peacock, Nicola Lewis, Ian Brown, John W. McCauley, Elma Tchilian   +13 more
wiley   +1 more source

Host-range shift of H3N8 canine influenza virus: a phylodynamic analysis of its origin and adaptation from equine to canine host

Veterinary Research, 2019
Prior to the emergence of H3N8 canine influenza virus (CIV) and the latest avian-origin H3N2 CIV, there was no evidence of a circulating canine-specific influenza virus.
Wanting He, Gairu Li, Ruyi Wang, Weifeng Shi, Kemang Li, Shilei Wang, Alexander Lai, Shuo Su   +7 more
doaj   +1 more source

Genetic and serologic surveillance of canine (CIV) and equine (EIV) influenza virus in Nuevo León State, México [PDF]

PeerJ, 2019
Background Despite the uncontrolled distribution of the Influenza A virus through wild birds, the detection of canine influenza virus and equine influenza virus in Mexico was absent until now.
Claudia B. Plata-Hipólito, Sibilina Cedillo-Rosales, Nelson Obregón-Macías, Carlos E. Hernández-Luna, Cristina Rodríguez-Padilla, Reyes S. Tamez-Guerra, Juan F. Contreras-Cordero   +6 more
doaj   +2 more sources

Viral factors in influenza pandemic risk assessment [PDF]

, 2016
The threat of an influenza A virus pandemic stems from continual virus spillovers from reservoir species, a tiny fraction of which spark sustained transmission in humans.
Barclay, Wendy, Beauchemin, Catherine A.A., Bedford, Trevor, Belser, Jessica A., Cobey, Sarah, Friedrich, Thomas C., Handel, Andreas, Herfst, Sander, Kasson, Peter M., Lipsitch, Marc, Lloyd-Smith, James O., Maurer-Stroh, Sebastian, Murcia, Pablo R., Raman, Rahul, Riley, Steven, Roche, Benjamin, Russell, Charles J., Russell, Colin A., Wilke, Claus O.   +18 more
core   +4 more sources

DNA Nanostructure‐Templated Multivalency Enables Broad‐Spectrum Virus Inhibition

Advanced Science, Volume 13, Issue 14, 9 March 2026.
A honeycomb‐shaped DNA nanostructure is introduced that organizes nanobodies or aptamers into trimeric clusters mirroring the native hemagglutinin arrangement on influenza viruses. This geometry‐matched multivalency enhances binding avidity by up to 1000‐fold, resulting in robust, broad‐spectrum viral neutralization and a 30–55% improvement in host ...
Saurabh Umrao, Abhisek Dwivedy, Dhanush Gandavadi, Chi Chen, Lifeng Zhou, Jinwei Duan, Vineetha Mareddy, Ying Fang, Xing Wang   +8 more
wiley   +1 more source