Evolutionary and Mutational Characterization of the First H5N8 Subtype Influenza A Virus in Humans [PDF]
Pathogens, 2022 Highly pathogenic influenza A virus H5 subtype remains a risk for transmission in humans. The H5N8 subtype has caused multiple outbreaks in poultry in Europe over the past few winters.
Lin Ding, Jie Li, Xue Li, Bingqian Qu
doaj +6 more sources
Construction and Immune Strategy Optimization of a Vaccine Strain for Influenza A (H5N8) Subtype [PDF]
VirusesMultiple subtypes of avian influenza virus (AIV), including H5N1, H5N6, and H5N8 viruses, are currently co-circulating in wild birds and poultry and causing sporadic human infections. Vaccine development is essential for pandemic preparedness.
Shuxia Zhang +14 more
doaj +4 more sources
Global review of the H5N8 avian influenza virus subtype [PDF]
Frontiers in Microbiology, 2023 Orthomyxoviruses are negative-sense, RNA viruses with segmented genomes that are highly unstable due to reassortment. The highly pathogenic avian influenza (HPAI) subtype H5N8 emerged in wild birds in China.
Saba Rafique +15 more
doaj +5 more sources
Novel Genotype of HA Clade 2.3.4.4b H5N8 Subtype High Pathogenicity Avian Influenza Virus Emerged at a Wintering Site of Migratory Birds in Japan, 2021/22 Winter [PDF]
PathogensSurveillance of avian influenza virus (AIV) was conducted in the 2021–2022 winter season at a wintering site of migratory Anatidae in Japan. An H5N8 subtype high pathogenicity AIV (HPAIV) with a unique gene constellation and four low pathogenicity AIVs ...
Berihun Dires Mihiretu +4 more
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Highly pathogenic avian influenza virus of the A/H5N8 subtype, clade 2.3.4.4b, caused outbreaks in Kazakhstan in 2020 [PDF]
PeerJ, 2022 Background Large poultry die-offs happened in Kazakhstan during autumn of 2020. The birds’ disease appeared to be avian influenza. Northern Kazakhstan was hit first and then the disease propagated across the country affecting eleven provinces. This study
Asylulan Amirgazin +7 more
doaj +6 more sources
Viruses, 2021 Highly pathogenic avian influenza (HPAI), a zoonotic disease, is a major threat to humans and poultry health worldwide. In January 2014, HPAI virus subtype H5N8 first infected poultry farms in South Korea, and 393 outbreaks, overall, were reported with ...
Woo-Hyun Kim, Sun Hak Bae, Seongbeom Cho
doaj +5 more sources
Viruses, 2020 In October 2020, a highly pathogenic avian influenza (HPAI) subtype H5N8 virus was identified from a fecal sample of a wild mandarin duck (Aix galericulata) in South Korea.
Sol Jeong +9 more
doaj +5 more sources
Pathogenicity of highly pathogenic avian influenza H5N8 subtype for herring gulls (Larus argentatus): impact of homo- and heterosubtypic immunity on the outcome of infection [PDF]
Veterinary Research, 2022 To improve understanding of the pathobiology of highly pathogenic avian influenza virus (HPAIV) infections in wild birds, pathogenicity and transmissibility of HPAIV H5N8 subtype clade 2.3.4.4b was evaluated in ~ 8-week-old herring gulls (Larus ...
Karolina Tarasiuk +8 more
doaj +3 more sources
A Monoclonal Antibody ELISA-Based Assay for Measuring the Potency of Candidate H5 Clade 2.3.4.4b Pandemic Influenza Vaccines. [PDF]
Influenza Other Respir VirusesABSTRACT Background The single radial immunodiffusion (SRID) assay is used to determine the potency of inactivated influenza vaccines. Nevertheless, development of alternative influenza vaccine potency assays with greater sensitivity and less reliance on large quantities of reference reagents is needed.
Odin M, Schmeisser F, Soto J, Weir JP.
europepmc +2 more sources
Highly pathogenic avian influenza A subtype H5N8
EFSA Journal, 2014 Highly pathogenic avian influenza (HPAI) H5N8 outbreaks in poultry farms have been reported in Asia and Europe since January and November 2014, respectively.
European Food Safety Authority +1 more
doaj +2 more sources