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Evolutionary and Mutational Characterization of the First H5N8 Subtype Influenza A Virus in Humans [PDF]

open access: yesPathogens, 2022
Highly pathogenic influenza A virus H5 subtype remains a risk for transmission in humans. The H5N8 subtype has caused multiple outbreaks in poultry in Europe over the past few winters.
Bingqian Qu
exaly   +4 more sources

Construction and Immune Strategy Optimization of a Vaccine Strain for Influenza A (H5N8) Subtype [PDF]

open access: yesViruses
Multiple subtypes of avian influenza virus (AIV), including H5N1, H5N6, and H5N8 viruses, are currently co-circulating in wild birds and poultry and causing sporadic human infections. Vaccine development is essential for pandemic preparedness.
Shuxia Zhang, Dayan Wang, Hejiang Wei
exaly   +4 more sources

Highly pathogenic avian influenza virus of the A/H5N8 subtype, clade 2.3.4.4b, caused outbreaks in Kazakhstan in 2020 [PDF]

open access: yesPeerJ, 2022
Background Large poultry die-offs happened in Kazakhstan during autumn of 2020. The birds’ disease appeared to be avian influenza. Northern Kazakhstan was hit first and then the disease propagated across the country affecting eleven provinces. This study
Asylulan Amirgazin   +7 more
doaj   +3 more sources

Pathogenicity of highly pathogenic avian influenza H5N8 subtype for herring gulls (Larus argentatus): impact of homo- and heterosubtypic immunity on the outcome of infection [PDF]

open access: yesVeterinary Research, 2022
To improve understanding of the pathobiology of highly pathogenic avian influenza virus (HPAIV) infections in wild birds, pathogenicity and transmissibility of HPAIV H5N8 subtype clade 2.3.4.4b was evaluated in ~ 8-week-old herring gulls (Larus ...
Karolina Tarasiuk   +8 more
doaj   +2 more sources

Novel Genotype of HA Clade 2.3.4.4b H5N8 Subtype High Pathogenicity Avian Influenza Virus Emerged at a Wintering Site of Migratory Birds in Japan, 2021/22 Winter [PDF]

open access: yesPathogens
Surveillance of avian influenza virus (AIV) was conducted in the 2021–2022 winter season at a wintering site of migratory Anatidae in Japan. An H5N8 subtype high pathogenicity AIV (HPAIV) with a unique gene constellation and four low pathogenicity AIVs ...
Berihun Dires Mihiretu   +4 more
doaj   +2 more sources

Serological Surveillance of Avian Influenza Virus Exposure Using Paired Sera Among Occupational Contacts in Taiwan, January-September 2025. [PDF]

open access: yesInfluenza Other Respir Viruses
ABSTRACT In 2025, Taiwan implemented paired sera surveillance among occupational contacts of avian influenza viruses (AIVs). Of 122 contacts analyzed, 117 (95.9%) remained asymptomatic with high personal protective equipment compliance (91.8%). No seroconversion was detected against AIV A(H5N2) clade 2.3.4.4b. These findings suggest a low risk of human
Lin CY   +7 more
europepmc   +2 more sources

Highly Pathogenic Avian Influenza Clade 2.3.4.4b Subtype H5N8 Virus Isolated from Mandarin Duck in South Korea, 2020

open access: yesViruses, 2020
In October 2020, a highly pathogenic avian influenza (HPAI) subtype H5N8 virus was identified from a fecal sample of a wild mandarin duck (Aix galericulata) in South Korea.
Yujin Kim, Chang-Seon Song, Dong-Hun Lee
exaly   +3 more sources

Nomenclature Updates to the Hemagglutinin Gene Clade Designations Resulting From the Continued Evolution of High Pathogenicity Avian Influenza A(H5) Virus Clades 2.3.2.1c and 2.3.4.4 [PDF]

open access: yesInfluenza Other Respir Viruses
ABSTRACT Background and Methods The evolutionary divergence of the A(H5) hemagglutinin (HA) gene of high pathogenicity avian influenza (HPAI) viruses (A/goose/Guangdong/96 lineage) was analyzed by phylogenetic and average pairwise distance methods to identify clades that merit nomenclature updates.
Lam T   +24 more
europepmc   +2 more sources

Spatiotemporal Dynamics of Highly Pathogenic Avian Influenza Subtype H5N8 in Poultry Farms, South Korea

open access: yesViruses, 2021
Highly pathogenic avian influenza (HPAI), a zoonotic disease, is a major threat to humans and poultry health worldwide. In January 2014, HPAI virus subtype H5N8 first infected poultry farms in South Korea, and 393 outbreaks, overall, were reported with ...
Seongbeom Cho, Sunhak Bae, Woo-Hyun Kim
exaly   +3 more sources

Emergence of Novel Highly Pathogenic Avian Influenza Virus A(H5N1) Clade 2.3.4.4b in Commercial Poultry, Bangladesh. [PDF]

open access: yesInfluenza Other Respir Viruses
ABSTRACT Background The high‐pathogenicity avian influenza (HPAI) viruses represent a main threat to animal and human health, poultry productivity, and ecosystems. The newly evolved A(H5N1) clade 2.3.4.4b has become a worldwide concern for its expanding multihost ecology, including poultry and a wide range of mammalian species.
Samad MA   +8 more
europepmc   +2 more sources

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