Results 91 to 100 of about 3,090 (189)

Do authoritarian institutions mobilize economic cooperation?

, 2009
Authoritarianism, Dictatorship, Taxation, Institutions, H24, H27, H71,
Abel Escribà-Folch, Escribà Folch, Abel (author)   +1 more
core   +1 more source

Vertical transfers and the appropriation of resources by the bureaucracy: the case of Brazilian state governments

, 2009
Intergovernmental grants, Bureaucracy, Appropriation, Public-private wage differential, H71, H77,
João Moura Neto, Nelson Marconi, Paulo E. M. Palombo, Marconi, Nelson, João S. Moura Neto, Palombo, Paulo Eduardo Moledo, Paulo Arvate, Arvate, Paulo Roberto, Paulo Palombo, Moura Neto, João Silva, Paulo R. Arvate   +10 more
core   +1 more source

Las aglomeraciones urbanas y los impuestos: algunas ideas derivadas de la aplicación de la curva de Laffer al impuesto sobre la renta español en diferentes escenarios espaciales

El Trimestre Económico, 2017
Antecedentes: La búsqueda de las tasas impositivas óptimas ha sido recurrente en las discusiones de política fiscal. En particular, la relación entre la estructura tributaria y el crecimiento económico ha hecho resurgir la ...
Laura Varela-Candamio, Fernando Rubiera Morollón   +1 more
doaj  

Tax mimicking among local governments: some evidence from Spanish municipalities

, 2010
Tax mimicking, Spatial econometrics, Local governments, H71, H73,
Delgado Rivero, Francisco José, Francisco J. Delgado, Francisco Delgado, Mayor Fernández, Matías, Mayor, Matías, Matías Mayor, Delgado, Francisco J.   +6 more
core   +1 more source

Phase 1b Study of the Epichaperome Inhibitor PU-H71 Administered Orally with Ruxolitinib Continuation for the Treatment of Patients with Myelofibrosis

Blood, 2019
Background: Myelofibrosis (MF) is a life-threatening disease characterized by splenomegaly, constitutional symptoms, and shortened survival. Although ruxolitinib, a JAK1/2 inhibitor, is approved for Intermediate or High-risk MF and can reduce the spleen size and improve quality of life, many patients discontinue due to loss of efficacy.
Naveen Pemmaraju, Krishna Gundabolu, Kristen Pettit, Moshe Talpaz, Nikolai A. Podoltsev, Gary J. Schiller, Peter Eisenberg, Hagop Youssoufian, Susan Duggan, Barbara Wallner, Srdan Verstovsek   +10 more
openaire   +1 more source

PTPN11 Mutated Acute Myeloid Leukemia (AML) Features an Abundant Epichaperome Network and Is Sensitive to the Epichaperome Inhibitor PU-H71

Blood, 2019
PTPN11 mutations occur in roughly 5-10% of AML patients. There is no defined impact on prognosis in the literature, although a single center analysis from our group suggested an association with poor outcomes. The pathogenesis of activating PTPN11 mutations is hypothesized to result in increased signaling through RAS resulting in uncontrolled cellular ...
Justin D. Kaner, Montreh Tavakkoli, Lisa Toudic, Brett M. Stevens, Craig T Jordan, Tony Taldone, Gabriela Chiosis, Ellen K. Ritchie, Pinkal Desai, Michael B. Samuel, Sangmin Lee, Gail J. Roboz, Monica L. Guzman   +12 more
openaire   +1 more source

Does Digital Literacy Mediate the Relationship bBetween ICT and Regional Own-Source Revenue?

ECONOMICS
This study examines the mediating role of digital literacy in the relationship between ICT development and regional own-source revenue across Indonesia’s 34 provinces from 2018 to 2022.
Priambodo Aji, Anwar Nurul, Suharno
doaj   +1 more source

Population aging as a factor limiting the revenue potential of local government units. A case study of gminas in Poland1

International Journal of Management and Economics
The purpose of the study is to determine the impact of demographic changes (depopulation, population aging) occurring in Polish local government units (LGUs), identified in this article with gminas (municipalities), on their revenue potential.
Szymkowiak Marcin, Wyszkowska Dorota
doaj   +1 more source

Inhibition of Hsp90 Suppresses PI3K/AKT/mTOR Signaling and Has Antitumor Activity in Burkitt Lymphoma

, 2017
Hsp90 is a molecular chaperone that protects proteins, including oncogenic signaling complexes, from proteolytic degradation. PU-H71 is a next-generation Hsp90 inhibitor that preferentially targets the functionally distinct pool of Hsp90 present in tumor
Jennifer E. Totonchy, Allison Rainey, Amy Chadburn, Filemon S. Dela Cruz, Herman J. van Besien, Andrew L. Kung, Tanner Dalton, Anna Rodina, Lisa Giulino-Roth, Alexander Bolaender, Tony Taldone, Ethel Cesarman, Matthew J. Barth, Hediye Erdjument-Bromage, Jouliana Sadek, Gabriela Chiosis   +15 more
core   +1 more source

Hsp90阻害剤PU-H71と炭素線照射の併用による癌抑制効果

, 2013
We have been studying the combined effect of Hsp90 inhibitors and carbon ion irradiation. Our recent investigation indicated that 17AAG, an effective Hsp90 inhibitor derived from geldanamycin, clearly gave radiosensitizing effect in SQ5 human lung tumor
李 惠子, 642131, 642130, 642133, 松本 孔貴, 642132, 642124, 藤森, 亮, 642135, 642134, 松本, 孔貴, 岡安 隆一, 正岡, 綾, 正岡 綾, 李, 惠子, 岡安, 隆一, 平川 博一, 642126, 642125, 642128, 642127, 642129, 平川, 博一, 藤森 亮   +23 more
core