Results 151 to 160 of about 9,490 (173)

Enhanced immune response of BMDCs pulsed with H9N2 AIV and CpG

Vaccine, 2014
Dendritic cells (DCs), professional antigen presenting cells, have demonstrated effective in controlling the initial of innate immune, while CpG could improve the performance of immune system. To explore the mechanism of CpG enhancing the immune response, we compared different stimulated mouse DCs with systemic approach microarrays.
Jian Lin, Tao Qin
exaly   +3 more sources

Heterologous post-infection immunity against Egyptian avian influenza virus (AIV) H9N2 modulates the course of subsequent infection by highly pathogenic AIV H5N1, but vaccination immunity does not

Journal of General Virology, 2017
In Egypt, zoonotic A/goose/Guangdong/1/96 (gs/GD-like) highly pathogenic avian influenza virus (HPAIV) H5N1 of clade 2.2.1.2 is entrenched in poultry populations and has co-circulated with low-pathogenic avian influenza virus H9N2 of the G1 lineage since 2010. Here, the impact of H9N2 infection or vaccination on the course of consecutive infection with
Mahmoud M Naguib, Martin Beer, Christian Grund   +2 more
exaly   +3 more sources

Chicken TCRγδ+CD8α+T cells are antigen-specific and protective in H9N2 AIV infection

Journal of Immunology
Abstract TCRγδ+ T cells are a major lymphocyte population of chickens, but their response or contribution to immunity against avian influenza virus (AIV) remains unknown. Here, we report an increase in the proportion and activation state of TCRγδ+CD8α+ T cells in the PBMCs of 3 chicken lines (MHC homozygous H-B2 and H-B21 lines and ...
Ming Liao, Adrian L Smith, Weisan Chen
exaly   +3 more sources

KRT10 plays an important role in the release of viral genome from endosomes during H9N2 subtype AIV replication in HeLa cells

Veterinary Microbiology, 2023
The infection and replication of avian influenza virus (AIV) in host cells is a complex biological process that involves the transport of viral genes through the host cell's transport systems. Actin, microtubules and vimentin are known to facilitate transport of endosomes to the perinuclear region, but the biological role of Keratin, another ...
Xiangyu, Huang, Guihu, Yin, Bin, Zhou, Yiqin, Cai, Jianing, Hu, Jingwen, Huang, Zili, Chen, Qingtao, Liu, Xiuli, Feng   +8 more
openaire   +2 more sources

Revealing novel and conservative T-cell epitopes with MHC B2 restriction on H9N2 avian influenza virus (AIV)

Journal of Biological Chemistry
B2 haplotype major histocompatibility complex (MHC) has been extensively reported to confer resistance to various avian diseases. But its peptide-binding motif is unknown, and the presenting peptide is rarely identified. Here, we identified its peptide-binding motif (X-A/V/I/L/P/S/G-X-X-X-X-X-X-V/I/L) in vitro using Random Peptide Library-based MHC I ...
Ming Liao, Yongxiu Yao, Manman Dai
exaly   +3 more sources

GoTLR7 but not GoTLR21 mediated antiviral immune responses against low pathogenic H9N2 AIV and Newcastle disease virus infection

Immunology Letters, 2017
Aquatic birds are considered the biological and genetic reservoirs of avian influenza virus and play a critical role in the transmission and dissemination of Newcastle Disease Virus (NDV). Both TLR7 and TLR21 are important for the host antiviral immune response.
Bing, Yan, Jinyue, Zhang, Wei, Zhang, Mingshu, Wang, Renyong, Jia, Dekang, Zhu, Mafeng, Liu, Qiao, Yang, Ying, Wu, Kunfeng, Sun, Xiaoyue, Chen, Anchun, Cheng, Shun, Chen   +12 more
openaire   +2 more sources

The host protein CCT8 interacts with PB2 protein of H9N2 AIV and facilitates virus replication

Avian Pathology
The host protein CCT8 interacts with the influenza virus protein PB2.The CCT8 gene is upregulated during influenza virus infection.Knockdown of CCT8 inhibits viral proliferation.Elevated expression of CCT8 facilitates viral proliferation.
Yiqin, Cai, Ye, Liu, Guihu, Yin, Jianing, Hu, Zichen, Gao, Xinyu, Guo, Ruiying, Wang, Meng, Zhong, Qingtao, Liu, Xiuli, Feng   +9 more
openaire   +2 more sources

[Molecular mechanism affecting route of transmission for H9N2 subtype AIV].

Wei sheng wu xue bao = Acta microbiologica Sinica, 2009
The available evidence suggests that H9 subtype avian influenza virus (AIV) did not circulate in Chicken flocks in China until the early 1990s. However, the pandemic of H9 subtype AI, which started in summer of 1998, spread very rapidly to more than 20 provinces within several months.
Huo-ying, Shi, Xiu-fan, Liu
openaire   +1 more source

Molecular identification and comparative transcriptional analysis of myxovirus resistance GTPase (Mx) gene in goose (Anser cygnoide) after H9N2 AIV infection

Comparative Immunology, Microbiology and Infectious Diseases, 2016
Interferon (IFN)-induced myxovirus resistance (Mx) GTPases belong to the family of dynamin-like GTPases and control a diverse range of viruses. In this study, the identified goose Mx (goMx) mRNA is 2009bp long, shares partially conserved exons with other homologues, and shares highly conserved domains in its primary structure.
Miao, Zeng, Shun, Chen, Mingshu, Wang, Renyong, Jia, Dekang, Zhu, Mafeng, Liu, Kunfeng, Sun, Qiao, Yang, Ying, Wu, Xiaoyue, Chen, Anchun, Cheng   +10 more
openaire   +2 more sources

Muscovy duck retinoic acid-induced gene I (MdRIG-I) functions in innate immunity against H9N2 avian influenza viruses (AIV) infections

Veterinary Immunology and Immunopathology, 2015
Retinoic acid inducible gene I (RIG-I) is a cytosolic pattern recognition receptor that senses pathogen-associated molecular patterns (PAMPs). Muscovy duck (Cairina moschata) is a large duck different from other species of ducks, and is more susceptible to some microbial pathogens.
Yuqiang, Cheng, Qingqing, Huang, Wenhui, Ji, Bin, Du, Qiang, Fu, Huiting, An, Jing, Li, Hengan, Wang, Yaxian, Yan, Chan, Ding, Jianhe, Sun   +10 more
openaire   +2 more sources