Results 21 to 30 of about 139,282 (292)

Vasopressin, insulin and peroxide(s) of vanadate (pervanadate) influence Na⁺ transport mediated by (Na⁺, K⁺)ATPase or Na⁺/H⁺ exchanger of rat liver plasma membrane vesicles [PDF]

European Journal of Biochemistry, 1990
Uptake of 22Na+ by liver plasma membrane vesicles, reflecting Na+ transport by (Na+, K+)ATPase or Na+/ H+ exchange was studied. Membrane vesicles were isolated from rat liver homogenates or from freshly prepared rat hepatocytes incubated in the presence of [Arg8]vasopressin or pervanadate and insulin.
JAKUBOWSKI, Josef, Jakob, Andrea
openaire   +3 more sources

Conformational rearrangement of gastric H+,K+-ATPase induced by an acid suppressant

Nature Communications, 2011
Acid-related gastric diseases are associated with disorder of digestive tract acidification. The gastric proton pump, H+,K+-ATPase, exports H+ in exchange for luminal K+ to generate a highly acidic environment in the stomach, and is a main target for ...
K. Abe, K. Tani, Y. Fujiyoshi
semanticscholar   +1 more source

Ellagic acid modulates Na+, H+ exchanger activity, Na+, K+ ATPases, and Ca2+ ATPases membrane transporters in tert-butyl hydroperoxide-induced oxidative stress during aging in humans

, 2023
Abstract Ellagic acid (EA), a dimer of gallic acid is mainly present in pomegranates and berries possessing health-promoting benefits via its antioxidant and anti-inflammatory properties. We have evaluated the in vitro activity of EA on Na+, H+ exchanger (NHE), Na+, K+ ATPases, and Ca2+ ATPases activity in the control and tert-butyl ...
Deepika ., Tikam Chand Dakal, Richa ., Pawan Kumar Maurya   +3 more
openaire   +1 more source

Effects of salinity challenge on the endocrine control of osmoregulation and calcium homeostasis in the sea bream [PDF]

, 1999
The gilthead sea bream (Sparus auratu) is a marine species often found in coastal lagoons, experimenting episodic exposures to both brackish and hypersaline environments.
Canario, Adelino V. M., Flik, G., Fuentes, J., Guerreiro, P. M., Power, Deborah   +4 more
core   +1 more source

A Quantitative Structure-Activity Relationship and Molecular Modeling Study on a Series of Biaryl Imidazole Derivatives Acting as H+/K+-ATPase Inhibitors

, 2013
The H+/K+-ATPase or proton pump is a magnesium-dependant enzyme which causes the exchange of a proton against a potassium ion through a membrane. Over activity of this enzyme causes hyperacidity by producing more of hydrochloric acid inside the stomach ...
N. Agarwal, A. Bajpai, Vivek Srivastava, Satya P. Gupta   +3 more
semanticscholar   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Solubilization and reconstitution of the gastric H,K-ATPase.

Journal of Biological Chemistry, 1985
Proteoliposomes containing the hog gastric H+,K+-ATPase were prepared from cholate and n-octyl glucoside extracts of native microsomes. Experiments were presented which show reconstitution-dependent selective purification of a 94-kDa peptide capable of ...
Edwin RabonS, R. Gunther, Annick Sournarmon, Sara Bassilian, Miguel Lewins, George Sachs   +5 more
semanticscholar   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

A genetic modifier screen identifies chromosomal intervals harboring potential midline interacting genes [PDF]

, 2011
This work investigates the growth of B-C-N layers by chemical vapor deposition using methylamine borane (MeAB) as single-source precursor. MeAB has been synthesized and characterized, paying particular attention to the analysis of its thermolysis ...
Ares, José Ramón, Betti, Maria Grazia, Demirci, Umit B., Ferrer, Isabel Jiménez, Flores, Eduardo, Galvis, Andrés R., García-García, F. Javier, Granados, Daniel, Leardini, Fabrice, Mariani, Carlo, Mastrangelo, Filippo, Molina, Pablo, Navarro, Cristina Gómez, Polin, Guillermo López, Sánchez, Carlos, Urbanos, Fernando J., van der Meulen, Herko P., Yot, Pascal G.   +17 more
core   +3 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source