Results 91 to 100 of about 1,250,237 (300)

Comparison of Global H i and Hα Line Profiles in MaNGA Galaxy Pairs with FAST

open access: yesThe Astrophysical Journal
We present case studies comparing the global H i and H α emission line profiles of six galaxy pairs. The six pairs are selected to have different nuclear activities, with two hosting an active galactic nucleus, and in different merging stages—two of each
Gaoxiang Jin   +5 more
doaj   +1 more source

Spectroscopic Studies of an Ultraluminous Supersoft X-Ray Source in M81

open access: yes, 2015
Ultraluminous supersoft X-ray sources (ULSs) exhibit supersoft X-ray spectra with blackbody temperatures below 0.1 keV and bolometric luminosities above 10$^{39}$ ergs s$^{-1}$.
Bai, Yu, Liu, JiFeng, Wang, Song
core   +1 more source

SPITZERSPECTRAL LINE MAPPING OF PROTOSTELLAR OUTFLOWS. III. H2EMISSION IN L1448, BHR71, AND NGC2071 [PDF]

open access: yesThe Astrophysical Journal, 2011
Spitzer-IRS maps of H_2 pure rotational lines from S(0) to S(7) in 3 outflows from Class 0 sources - L1448, BHR71, and NGC2071 - are presented. These lines are used, in conjunction with available rovibrational, near-IR H_2 lines, to probe the physical conditions of the warm gas between hundreds and thousands of Kelvin.
Giannini, Teresa   +5 more
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

FAST Search for Circumstellar Atomic Hydrogen. II. Is BD+30°3639 an Interacting Planetary Nebula?

open access: yesThe Astrophysical Journal, 2023
The young, compact, very high surface brightness but low excitation planetary nebula (PN) BD+30°3639 is one of the very few PNe that have been reported to exhibit the 21 cm H i emission line.
Xu-Jia Ouyang   +5 more
doaj   +1 more source

THE MOSDEF SURVEY: DISSECTING THE STAR FORMATION RATE VERSUS STELLAR MASS RELATION USING HαAND HβEMISSION LINES ATz∼ 2 [PDF]

open access: yesThe Astrophysical Journal, 2015
Author(s): Shivaei, I; Reddy, NA; Shapley, AE; Kriek, M; Siana, B; Mobasher, B; Coil, AL; Freeman, WR; Sanders, R; Price, SH; Groot, LD; Azadi, M | Abstract: We present results on the star formation rate (SFR) versus stellar mass (M∗) relation (i.e., the "main sequence") among star-forming galaxies at 1.37 ≤ z ≤ 2.61 using the MOSFIRE Deep Evolution ...
Irene Shivaei   +11 more
openaire   +3 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

The Formation of IRIS Diagnostics. IX. The Formation of the C I 135.58 Line in the Solar Atmosphere

open access: yes, 2017
The C I 135.58 line is located in the wavelength range of NASA's Interface Region Imagin Spectrograph (IRIS) small explorer mission. We here study the formation and diagnostic potential of this line by means of non local-thermodynamic-equilibrium ...
Carlsson, Mats   +2 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

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