Results 71 to 80 of about 1,250,237 (300)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

H i, FRB, What’s Your z: The First FRB Host Galaxy Redshift from Radio Observations

open access: yesThe Astrophysical Journal Letters
Identification and follow-up observations of the host galaxies of fast radio bursts (FRBs) not only help us understand the environments in which the FRB progenitors reside, but also provide a unique way of probing the cosmological parameters using the ...
M. Glowacki   +12 more
doaj   +1 more source

Probable identification of the on-disk counterpart of spicules in Hinode Ca II H observations

open access: yes, 2012
I present a study of high-resolution time series of Ca II H images and Fe I 630.15 nm spectra taken with the Solar Optical Telescope on the Hinode spacecraft.
de Wijn, A. G.
core   +1 more source

SPITZERSPECTRAL LINE MAPPING OF PROTOSTELLAR OUTFLOWS. II. H2EMISSION IN L1157 [PDF]

open access: yesThe Astrophysical Journal, 2010
31 pages, 9 figure, Accepted for publication on ...
Nisini, B.   +6 more
openaire   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

A Detection of Cosmological 21 cm Emission from CHIME in Cross-correlation with eBOSS Measurements of the Lyα Forest

open access: yesThe Astrophysical Journal
We report the detection of 21 cm emission at an average redshift $\bar{z}=2.3$ in the cross-correlation of data from the Canadian Hydrogen Intensity Mapping Experiment (CHIME) with measurements of the Ly α forest from eBOSS.
Mandana Amiri   +30 more
doaj   +1 more source

H2infrared line emission across the bright side of theρOphiuchi main cloud [PDF]

open access: yesAstronomy & Astrophysics, 2002
We present imaging and spectroscopic observations of dust and gas (H2) emission, obtained with ISO, from the western edge of the ρ Ophiuchi molecular cloud illuminated by the B2 star HD147889 (χ ∼ 400). This photodissociation region (PDR) is one of the nearest PDRs to the Sun (d = 135 ± 15 pc from the stellar parallax) and the layer of UV light ...
E. Habart   +5 more
openaire   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

The Magnitude of the Dark Ages 21 cm Signal in the Context of Existing Early and Late Time Constraints on ΛCDM

open access: yesThe Astrophysical Journal Letters
The dark ages 21 cm signal is a promising probe of the currently unobserved infant Universe between the formation of the cosmic microwave background around z  ≈ 1100 and the first galaxies around z  ≈ 30.
Harry T. J. Bevins
doaj   +1 more source

Improving accretion diagnostics for young stellar objects with mid-infrared hydrogen lines from JWST/MIRI

open access: yesAstronomy & Astrophysics
Context. We present a comprehensive study of mid-infrared neutral hydrogen (H i) emission lines in 79 nearby (d < 200 pc) young stars using the James Webb Space Telescope (JWST) Mid-Infrared Instrument (MIRI).
Shridharan B.   +12 more
doaj   +1 more source

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