Results 81 to 90 of about 35,694,720 (305)
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
The Astrophysical JournalSeveral ongoing and upcoming radio telescopes aim to detect either the global 21 cm signal or the 21 cm power spectrum. The extragalactic radio background, as detected by ARCADE-2 and LWA-1, suggests a strong radio background from cosmic dawn, which can ...
Sudipta Sikder +2 more
doaj +1 more source
H2infrared line emission across the bright side of theρOphiuchi main cloud [PDF]
Astronomy & Astrophysics, 2002 We present imaging and spectroscopic observations of dust and gas (H2) emission, obtained with ISO, from the western edge of the ρ Ophiuchi molecular cloud illuminated by the B2 star HD147889 (χ ∼ 400). This photodissociation region (PDR) is one of the nearest PDRs to the Sun (d = 135 ± 15 pc from the stellar parallax) and the layer of UV light ...
E. Habart +5 more
openaire +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Variability study of the Hβ emission line in the blazar PKS 1510-089 [PDF]
, 2023 Blazars are a type of active galactic nucleus (AGN) characterized by their intense and variable emissions across the electromagnetic spec- trum, from radio to -rays.
Alfredo Amador-Portes
core
Survey of H{\alpha} emission-line stars in the star-forming region IC 5070
, 2023 Actively accreting young stellar objects show H$\alpha$ emission line in their spectra. We present the results of survey for H$\alpha$ emission-line stars in the star-forming region IC~5070 taken with 2-m Himalyan {\it Chandra} Telescope. Based on the H$\
Panwar, Neelam +5 more
core +1 more source
Comparison of Global H i and Hα Line Profiles in MaNGA Galaxy Pairs with FAST
The Astrophysical JournalWe present case studies comparing the global H i and H α emission line profiles of six galaxy pairs. The six pairs are selected to have different nuclear activities, with two hosting an active galactic nucleus, and in different merging stages—two of each
Gaoxiang Jin +5 more
doaj +1 more source
Spectroscopic observations of Hαemission-line stars from Sanduleak & Stephenson's 1973 (SS73) list [PDF]
Astronomy & Astrophysics, 2003 We present spectroscopic observations of 33 emission line stars from the Sanduleak & Stephenson's (1973) list. This work is part of a program to investigate emission-line objects in the southern hemisphere whose nature is not well established in the literature.
C. B. Pereira +2 more
openaire +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
, 2011 Context. We present deep spectroscopy of a large sample of low-metallicity emission-line galaxies. Aims. The main goal of this study is to derive element abundances in these low-metallicity galaxies. Methods.
Guseva, N. G. +16 more
core +1 more source