Results 61 to 70 of about 1,094,944 (319)
The Metallicity–Electron Temperature Relationship in H ii Regions
The Astrophysical JournalH ii region heavy-element abundances throughout the Galactic disk provide important constraints to theories of the formation and evolution of the Milky Way.
Dana S. Balser, Trey V. Wenger
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Expansion Signatures in 35 H II Regions Traced by SOFIA [C II] Emission
The Astrophysical JournalWe analyze the expansion signatures of 35 H II regions mapped in [C II ] 158 μ m emission by the Stratospheric Observatory for Infrared Astronomy. The [C II ] emission primarily traces photodissociation regions (PDRs) at the transition between ionized ...
T. Faerber +8 more
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FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
The Astrophysical JournalWe investigate the emergence phase of young star clusters in the nearby spiral galaxy NGC 628. We use JWST NIRCam and MIRI observations to create spatially resolved maps of the Pa α 1.87 μ m and Br α 4.05 μ m hydrogen recombination lines, as well as 3.3 ...
Alex Pedrini +23 more
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Electron Density Distribution in H ii Regions in IC 10
The Astronomical JournalWe present the [O III ] λ 52 μ m map of the dwarf galaxy IC 10 obtained with the Field-Imaging Far-Infrared Line Spectrometer on board the Stratospheric Observatory for Infrared Astronomy.
Fiorella L. Polles +9 more
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In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The Astrophysical JournalWe present the variations in far-ultraviolet (FUV) and H α star formation rates (SFR), SFR _UV and SFR _H _α , respectively, at subkiloparsec scales in 11 galaxies as part of the Deciphering the Interplay between the Interstellar Medium, Stars, and the ...
Mansi Padave +5 more
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Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source