Results 81 to 90 of about 1,149,495 (269)

Low-mass Stellar and Substellar Content of the Young Cluster Berkeley 59

The Astronomical Journal
We present a multiwavelength analysis of the young star cluster Berkeley 59, based on Gaia data and deep IR observations with the 3.58 m Telescopio Nazionale Galileo and Spitzer space telescope.
Neelam Panwar, Rishi C., Saurabh Sharma, Devendra K. Ojha, Manash R. Samal, H. P. Singh, Ram Kesh Yadav   +6 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Absorption and Self-absorption of [C ii] and [O i] Far Infrared Lines toward a Bright Bubble in the Nessie Infrared Dark Cloud

The Astrophysical Journal
Using the upGREAT instrument on board the Stratospheric Observatory for Infrared Astronomy, we imaged [C ii ] 157.74 and [O i ] 63.18 μ m line emission from a bright photodissociation region (PDR) associated with an ionized bubble located in the Nessie ...
James M. Jackson, J. Scott Whitaker, Edward Chambers, Robert Simon, Cristian Guevara, David Allingham, Philippa Patterson, Nicholas Killerby-Smith, Jacob Askew, Thomas Vandenberg, Howard A. Smith, Patricio Sanhueza, Ian W. Stephens, Lars Bonne, Fiorella L. Polles, Anika Schmiedeke, Netty Honigh, Matthias Justen   +17 more
doaj   +1 more source

Properties of H II region populations in galaxies. I - The first-ranked H II regions

The Astrophysical Journal, 1988
H-alpha photometry of the brightest H II regions in 95 nearby spiral and irregular galaxies has been analyzed in order to study the dependence of the H II region populations on the properties of their parent galaxies. It is found that the brightest H II regions in Magellanic irregular galaxies are about 50 times brighter than those in early-type ...
openaire   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Spectral Microlensing of Extragalactic H II Regions by Stellar-mass Black Holes

The Astrophysical Journal Letters
Most of the Milky Way’s predicted stellar-mass black holes remain hidden, especially at high Galactic latitudes or in the Galactic halo, where traditional dense-field stellar microlensing is ineffective.
Dezi Liu
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Fluorescence of [Fe II] in H II regions

, 1999
A study of [Fe II] lines at various positions within the H II regions M42 and M43 is presented. The relative intensities of selected optical [Fe II] lines are shown to be correlated with the intensity of the apparent nebular continuous spectrum. Since the continuum of H II regions is known to be mostly stellar radiation scattered by dust intermixed ...
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source