Results 61 to 70 of about 1,144,964 (311)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The Astrophysical JournalH ii region electron temperatures are a critical ingredient in metallicity determinations, and recent observations have revealed systematic variations in the temperatures measured using different ions.
Ryan J. Rickards Vaught +14 more
doaj +1 more source
Observations of the Galaxy NGC 3077 in the Narrow-Band [S II] and Hα Filters
Open Astronomy, 2011 We present observations of the H I tidal arm near a dwarf galaxy NGC 3077 (member of the M81 galaxy group) in the narrow-band [S II] and Hα filters. Observations were carried out in 2011 March with the 2 m RCC telescope at the NAO Rozhen, Bulgaria.
Andjelić M. +4 more
doaj +1 more source
New Infrared Sources Associated with H II Regions [PDF]
Symposium - International Astronomical Union, 1973 Photometry and mapping in the wavelength range 1.65–20 μ of the H II regions W3 and NGC 7538 have led to the discovery of a dozen new infrared emission sources. The sources have flux densities ranging up to 10–23 Wm–2 Hz–1 at 20 μ and diameters from < 3 to 40″.
C. G. Wynn-Williams +2 more
openaire +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Resonant Scattering of the He i 1.0833 μm Triplet in H ii Regions: Emission Spectra
The Astrophysical JournalResonant scattering of He i 1.0833 μ m triplet photons by metastable He 2 ^3 S _1 is studied for optical depths characteristic of H ii regions. Regions with large He 2 ^3 S _1 column densities are predicted to have unusually broad multipeaked 1.0833 μ m ...
B. T. Draine
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The Astrophysical JournalThe abundance discrepancy problem refers to the systematic differences observed between chemical abundances derived from collisionally excited lines (CELs) and recombination lines (RLs) of heavy ions.
Amrita Singh +21 more
doaj +1 more source
EMISSION LINE OBSERVATIONS OF H II REGIONS [PDF]
Symposium - International Astronomical Union, 1981 Optical observations provide a wealth of information on atomic abundances, the excitation (level of ionization), the kinetic temperature, and the density of the gas in H II regions. However, obscuration by dust limits optical observations of galactic H II regions to those which are nearby (within a few kpc) and which are unobscured by the molecular ...
openaire +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source