Results 61 to 70 of about 1,149,495 (269)

FEAST: Feedback in Emerging extragAlactic Star ClusTers: JWST Spots Polycyclic Aromatic Hydrocarbon Destruction in NGC 628 during the Emerging Phase of Star Formation

open access: yesThe Astrophysical Journal
We investigate the emergence phase of young star clusters in the nearby spiral galaxy NGC 628. We use JWST NIRCam and MIRI observations to create spatially resolved maps of the Pa α 1.87 μ m and Br α 4.05 μ m hydrogen recombination lines, as well as 3.3 ...
Alex Pedrini   +23 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Expansion Signatures in 35 H II Regions Traced by SOFIA [C II] Emission

open access: yesThe Astrophysical Journal
We analyze the expansion signatures of 35 H II regions mapped in [C II ] 158 μ m emission by the Stratospheric Observatory for Infrared Astronomy. The [C II ] emission primarily traces photodissociation regions (PDRs) at the transition between ionized ...
T. Faerber   +8 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Electron Density Distribution in H ii Regions in IC 10

open access: yesThe Astronomical Journal
We present the [O III ] λ 52 μ m map of the dwarf galaxy IC 10 obtained with the Field-Imaging Far-Infrared Line Spectrometer on board the Stratospheric Observatory for Infrared Astronomy.
Fiorella L. Polles   +9 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

JWST’s First View of the Most Vigorously Star-forming Cloud in the Galactic Center: Sagittarius B2

open access: yesThe Astronomical Journal
We report JWST NIRCAM and MIRI observations of Sgr B2, one of the most active sites of star formation in the Galaxy. These observations, using 14 filters spanning 1.5–25 μ m, have revealed a multilayered and highly structured cloud that contains both a ...
Nazar Budaiev   +11 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The Coevolution of Stellar Wind-blown Bubbles and Photoionized Gas. I. Physical Principles and a Semianalytic Model

open access: yesThe Astrophysical Journal
We propose a new framework for the simultaneous feedback of stellar winds and photoionizing radiation from massive stars, distinguishing the locations where forces are applied, and consequences for internal spatiotemporal evolution of the whole feedback ...
Lachlan Lancaster   +5 more
doaj   +1 more source

Distance to Sh2–106 from Gaia DR3 and its embedded radio population: Implications for a candidate explosive outflow

open access: yesAstronomy & Astrophysics
Sh2–106 has recently been proposed as a candidate explosive molecular outflow, but the physical interpretation of the region depends critically on its distance.
Dzib Sergio A.
doaj   +1 more source

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