Results 101 to 110 of about 3,875,215 (299)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The Astrophysical Journal, 1982 Observations of the molecular gas surrounding the biconical H II region S106 reveal a approx.100 M/sub sun/ disk constraining the development of the ionized region. Two CO peaks are seen in the equatorial plane of the biconical nebula on opposite sides of a near infrared source thought to be the exciting star for the H II region. Although no systematic
J. Bally, N. Z. Scoville
openaire +1 more source
, 2016 Using the short-high module of the Infrared Spectrograph on the Spitzer Space Telescope, we have measured the [S IV] 10.51, [Ne II] 12.81, [Ne III] 15.56, and [S III] 18.71-micron emission lines in nine H II regions in the dwarf irregular galaxy NGC 6822.
Colgan, Sean W. J. +7 more
core +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Magnetic Field Alignment Relative to Multiple Tracers in the High-mass Star-forming Region RCW 36
The Astrophysical JournalWe use polarization data from SOFIA HAWC+ to investigate the interplay between magnetic fields and stellar feedback in altering gas dynamics within the high-mass star-forming region RCW 36, located in Vela C.
Akanksha Bij +11 more
doaj +1 more source
The Astronomical Journal, 1990 New H-alpha images are presented of IC 1613, a small irregular galaxy in the Local Group. The images, obtained with a CCD on the 42-in telescope at Lowell Observatory, have been calibrated and used to produce an H-alpha luminosity function and a size distribution for the H II regions in IC 1613.
Jill S. Price +2 more
openaire +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Spectroscopy of Supernova Remnants and Candidates in M31
The Astrophysical JournalWith a star formation rate of order 0.4 M _⊙ yr ^−1 , M31 should have a significant population of supernova remnants (SNRs) and, in fact, 156 SNRs and SNR candidates have been suggested by J. H. Lee & M. G.
Nelson Caldwell +3 more
doaj +1 more source