Results 121 to 130 of about 20,346,263 (306)
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
The Wise Catalog Of Galactic H Ii Regions [PDF]
, 2014 Using data from the all-sky Wide-Field Infrared Survey Explorer (WISE) satellite, we made a catalog of over 8000 Galactic H II regions and H II region candidates by searching for their characteristic mid-infrared (MIR) morphology.
Wenger, T. V. +6 more
core
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Detection of Diffuse Hot Gas around the Young, Potential Superstar Cluster H72.97–69.39
The Astrophysical JournalWe present the first Chandra X-ray observations of H72.97–69.39, a highly embedded, potential superstar cluster in its infancy located in the star-forming complex N79 of the Large Magellanic Cloud. We detect particularly hard, diffuse X-ray emission that
Trinity L. Webb +8 more
doaj +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Evolutionary models for high-metallicity giant extragalactic H II regions
, 1994 This is an electronic version of an article published in The Astrophysical Journal Supplement Series. García Vargas, M.L. and A.I. Díaz. Evolutionary models for high-metallicity giant extragalactic H II regions.
García Vargas, María Luisa +1 more
core +1 more source
The Astrophysical JournalThe kinematic evolution of hypercompact (HC) H ii regions around young high-mass stars remains poorly understood due to complex interactions with parental environs.
Siju Zhang +21 more
doaj +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Investigating H II Regions in the Disk of NGC 7331 with the Circumgalactic Hα Spectrograph
The Astrophysical JournalWe investigate the ionized gas kinematics of H ii regions in the disk of NGC 7331 using integral field unit data collected with the Circumgalactic H α Spectrograph (CH α S).
Nazende ipek Kerkeser +5 more
doaj +1 more source