Results 131 to 140 of about 1,149,495 (269)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Splice Type-Specific Effects of Gαo Subunits on Cerebellar Anatomy and Synapse Formation. [PDF]

J Neurochem
Höltje M, Wolkowicz A, Ahnert-Hilger G.
europepmc   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Automated H-Scoring in Muscle-Invasive Bladder Cancer IHC: An Internal Validation Study. [PDF]

Diagnostics (Basel)
Yap M, Mihai IM, Alanazi MAA, Olteanu GE, Contreras-Sanz A, Black P, Wang G.   +6 more
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Dynamic analysis of the fractional distributed delay models. [PDF]

Sci Rep
El-Saka HAA, El-Sherbeny DEA, El-Sayed AMA.   +2 more
europepmc   +1 more source

The Formation of H II Regions. II.

The Astrophysical Journal, 1963
openaire   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

DNA Scission by Non-Histidine Amino-Terminal Cu(II) and Ni(II) Binding-Like Peptides. [PDF]

Chembiochem
Müller LK, Zhdanova H, Unksov IN, Gräwe A, Stahl J, Stein V, Tietze D, Tietze AA.   +7 more
europepmc   +1 more source

The Nearest H II Regions.

The Astrophysical Journal, 1952
Stewart Sharpless, Donald Osterbrock
openaire   +1 more source