Results 111 to 120 of about 3,875,215 (299)

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Characterizing Stellar and Gas Properties in NGC 628: Spatial Distributions, Radial Gradients, and Resolved Scaling Relations

open access: yesThe Astrophysical Journal
Building on our previous research involving multiwavelength data from UV to IR, we employ spectroscopic observations of ionized gas, as well as neutral hydrogen gas obtained from the Five-hundred Meter Aperture Spherical Telescope (FAST), to explore the ...
Peng Wei   +10 more
doaj   +1 more source

Properties of H II region populations in galaxies. I - The first-ranked H II regions

open access: yesThe Astrophysical Journal, 1988
H-alpha photometry of the brightest H II regions in 95 nearby spiral and irregular galaxies has been analyzed in order to study the dependence of the H II region populations on the properties of their parent galaxies. It is found that the brightest H II regions in Magellanic irregular galaxies are about 50 times brighter than those in early-type ...
openaire   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

NGC 628 in SIGNALS: Explaining the Abundance-ionization Correlation in H ii Regions

open access: yesThe Astrophysical Journal
The variations of oxygen abundance and ionization parameter in H ii regions are usually thought to be the dominant factors that produced variations seen in observed emission-line spectra. However, if and how these two quantities are physically related is
Ray Garner III   +7 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Detection of Diffuse Hot Gas around the Young, Potential Superstar Cluster H72.97–69.39

open access: yesThe Astrophysical Journal
We present the first Chandra X-ray observations of H72.97–69.39, a highly embedded, potential superstar cluster in its infancy located in the star-forming complex N79 of the Large Magellanic Cloud. We detect particularly hard, diffuse X-ray emission that
Trinity L. Webb   +8 more
doaj   +1 more source

Fluorescence of [Fe II] in H II regions

open access: yes, 1999
A study of [Fe II] lines at various positions within the H II regions M42 and M43 is presented. The relative intensities of selected optical [Fe II] lines are shown to be correlated with the intensity of the apparent nebular continuous spectrum. Since the continuum of H II regions is known to be mostly stellar radiation scattered by dust intermixed ...
openaire   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

ALMA-QUARKS: Few-thousand-year “Hatching out of the Egg:” The Supersonic Breakout of a Hypercompact H II Region from Its Parental Hot Core

open access: yesThe Astrophysical Journal
The kinematic evolution of hypercompact (HC) H ii regions around young high-mass stars remains poorly understood due to complex interactions with parental environs.
Siju Zhang   +21 more
doaj   +1 more source

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