Results 71 to 80 of about 3,849,349 (342)

FEAST: Feedback in Emerging extragAlactic Star ClusTers: JWST Spots Polycyclic Aromatic Hydrocarbon Destruction in NGC 628 during the Emerging Phase of Star Formation

open access: yesThe Astrophysical Journal
We investigate the emergence phase of young star clusters in the nearby spiral galaxy NGC 628. We use JWST NIRCam and MIRI observations to create spatially resolved maps of the Pa α 1.87 μ m and Br α 4.05 μ m hydrogen recombination lines, as well as 3.3 ...
Alex Pedrini   +23 more
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Expansion Signatures in 35 H II Regions Traced by SOFIA [C II] Emission

open access: yesThe Astrophysical Journal
We analyze the expansion signatures of 35 H II regions mapped in [C II ] 158 μ m emission by the Stratospheric Observatory for Infrared Astronomy. The [C II ] emission primarily traces photodissociation regions (PDRs) at the transition between ionized ...
T. Faerber   +8 more
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Electron Density Distribution in H ii Regions in IC 10

open access: yesThe Astronomical Journal
We present the [O III ] λ 52 μ m map of the dwarf galaxy IC 10 obtained with the Field-Imaging Far-Infrared Line Spectrometer on board the Stratospheric Observatory for Infrared Astronomy.
Fiorella L. Polles   +9 more
doaj   +1 more source

Star formation associated with a large-scale infrared bubble

open access: yes, 2014
Using the data from the Galactic Ring Survey (GRS) and Galactic Legacy Infrared Mid-Plane Survey Extraordinaire (GLIMPSE), we performed a study for a large-scale infrared bubble with a size of about 16 pc at a distance of 2.0 kpc. We present the 12CO J=1-
Ju, Bing-Gang, Xu, Jin-Long
core   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

The Coevolution of Stellar Wind-blown Bubbles and Photoionized Gas. I. Physical Principles and a Semianalytic Model

open access: yesThe Astrophysical Journal
We propose a new framework for the simultaneous feedback of stellar winds and photoionizing radiation from massive stars, distinguishing the locations where forces are applied, and consequences for internal spatiotemporal evolution of the whole feedback ...
Lachlan Lancaster   +5 more
doaj   +1 more source

Understanding Spatial and Spectral Morphologies of Ultracompact H II Regions

open access: yes, 2010
The spatial morphology, spectral characteristics, and time variability of ultracompact H II regions provide strong constraints on the process of massive star formation.
Arthur   +40 more
core   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

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