Results 41 to 50 of about 24,475 (136)

Public Health Achievements in Rwanda: A 21st Century Transformation

Public Health Challenges, Volume 5, Issue 2, June 2026.
This narrative review examines Rwanda's post‐2000 public health transformation using the WHO health system building blocks. It shows how strategic governance, universal health coverage via mutuelle de santé, community health workers, and digital health tools have driven substantial gains in maternal/child health, infectious disease control, and ...
Niyibizi Julius, Mugisha John, Nizeyimana Emmanuel   +2 more
wiley   +1 more source

The HIV Reservoir in the Female Reproductive Tract

American Journal of Reproductive Immunology, Volume 95, Issue 6, June 2026.
ABSTRACT Antiretrovirals can prevent the spread of replicating HIV within the host and decrease the virus in plasma to levels undetectable in clinical assays, and in genital secretions to untransmissible levels. However, during effective treatment with antiretrovirals, infectious HIV persists lifelong because the virus integrates into the host's DNA ...
Sean M. Hughes, Lisa M. Frenkel
wiley   +1 more source

Pharmacokinetics, Pharmacodynamics, Efficacy and Drug Resistance Selection of Injectable Long‐Acting Lenacapavir Pre‐Exposure Prophylaxis (PrEP) Against HIV

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 5, May 2026.
ABSTRACT Oral pre‐exposure prophylaxis (PrEP) can substantially reduce HIV infection risk when taken as prescribed. However, many individuals struggle adhering to the daily regimen. Twice‐yearly injections of the novel HIV capsid inhibitor lenacapavir (LEN) demonstrated potential in recent PrEP trials.
Hee‐yeong Kim, Antonia Liebenberg, Lanxin Zhang, Max von Kleist   +3 more
wiley   +1 more source

Unmasking Immune Reconstitution Inflammatory Syndrome (IRIS) : A report of five cases and review of the literature

Sultan Qaboos University Medical Journal, 2011
Immune reconstitution inflammatory syndromes (IRIS) in patients with acquired immune deficiency syndrome (AIDS) are characterised by atypical manifestations of opportunistic pathogens.
Abdullah Balkhair, Sudheer Ahamed, Dilip Sankhla   +2 more
doaj  

Clinical features and treatment effect of HIV-associated immune thrombocytopenia—single center Ten-Years data summary

Platelets, 2023
Thrombocytopenia represents one of the most prevalent hematologic complications observed in patients infected with the human immunodeficiency virus (HIV). In this study, we sought to analyze the clinical characteristics and treatment outcomes of patients
YaXian Tan, Lei Che, Hui Bi, ShanShan Fan, ZePing Zhou, HaiYan Min   +5 more
doaj   +1 more source

Microglial reactivity and nodule formation are associated with Synaptodendritic damage in the brains of people with HIV‐1

Brain Pathology, Volume 36, Issue 3, May 2026.
Despite effective ART, neurocognitive impairment persists in people with HIV. Brains from PWH present exacerbated microgliosis and formation of microglial nodules that are actively engaged in neuronal phagocytosis, resulting in neuronal injury and dendritic loss.
Roberta S. Dos Reis, Lauren A. Ignatz, Sathish Selvam, Marc C. E. Wagner, Sara Gianella, Antoine Chaillon, Vanessa Gomez‐Moreno, Jeremy Martison, Leah H. Rubin, Sabina Heberlen, Valentina Stosor, Jordan Lake, Velpandi Ayyavoo   +12 more
wiley   +1 more source

Sexuality in patients with human immunodeficiency virus at Embhuleni Hospital in Mpumalanga province

South African Family Practice, 2013
Objectives: This study explored issues of sexuality in people living with AIDS who were on highly active antiretroviral therapy (HAART). Design: This was a descriptive quantitative study.
E. de Vries, L. Gwyther, M. Mkhabela
doaj   +1 more source

Considerations for the Use of AAV‐based Gene Therapy in HIV‐Positive Individuals With Haemophilia

Haemophilia, Volume 32, Issue 3, Page 584-592, May/June 2026.
ABSTRACT Introduction There is a high prevalence of human immunodeficiency virus (HIV) infection among the haemophilia community due to treatment in the 1970s and 1980s with contaminated clotting factor. Lifelong treatment regimens for haemophilia and HIV are burdensome alone and pose a particular challenge for individuals living with both conditions ...
Jürgen K. Rockstroh, Julia C. Stingl, Marco Stadler, Anja Reichert, Heiner Wedemeyer, Johannes Oldenburg   +5 more
wiley   +1 more source

Risk Factors for the Development of Tuberculosis Among HIV-Positive Adults Under Highly Active Antiretroviral Therapy at Government Hospitals in Amhara Region, Ethiopia

International Journal of General Medicine, 2022
Awoke Seyoum Tegegne,1 Molalign Tarekegn Minwagaw2 1Department of Statistics, Bahir Dar University, Bahir Dar, Ethiopia; 2Department of Public Health, Amhara Community Health Institution, Bahir Dar, EthiopiaCorrespondence: Awoke Seyoum Tegegne ...
Tegegne AS, Minwagaw MT
doaj  

Adherence to highly active antiretroviral treatment in HIV-infected Rwandan women. [PDF]

PLoS ONE, 2011
Scale-up of highly active antiretroviral treatment therapy (HAART) programs in Rwanda has been highly successful but data on adherence is limited. We examined HAART adherence in a large cohort of HIV+ Rwandan women.The Rwanda Women's Interassociation ...
Stephenson Musiime, Fred Muhairwe, Alfred Rutagengwa, Eugene Mutimura, Kathryn Anastos, Donald R Hoover, Shi Qiuhu, Elizaphane Munyazesa, Ivan Emile, Annette Uwineza, Ethan Cowan   +10 more
doaj   +1 more source