Results 51 to 60 of about 24,694 (138)

Human immunodeficiency virus and intraocular inflammation in the era of highly active anti retroviral therapy – An update

open access: yesIndian Journal of Ophthalmology, 2020
Intraocular inflammation in patients with human immunodeficiency virus (HIV) infection is commonly due to infectious uveitis. Ocular lesions due to opportunistic infections (OI) are the most common and have been described extensively in the pre highly ...
Sridharan Sudharshan   +4 more
doaj   +1 more source

Temporal shifts in antiretroviral therapy regimens and metabolic outcomes in people living with HIV: A systematic review and meta‐analysis

open access: yesHIV Medicine, Volume 27, Issue 9, Page 1399-1420, September 2026.
Abstract Introduction Antiretroviral therapy (ART) for people living with HIV has led to dramatically reduced mortality and improved life expectancy. This achievement is accompanied by a higher risk for metabolic and other non‐communicable diseases. The role and contribution of various ART regimens to adverse metabolic outcomes are not fully understood.
Melani Ratih Mahanani   +7 more
wiley   +1 more source

Performance of Clinical Criteria for Screening of Possible Antiretroviral Related Mitochondrial Toxicity in HIV-Infected Children in Accra

open access: yesAIDS Research and Treatment, 2013
Mitochondrial damage is implicated in highly active antiretroviral therapy (HAART) toxicity. HIV infection also causes mitochondrial toxicity (MT). Differentiating between the two is critical for HIV management.
Allison Langs-Barlow   +4 more
doaj   +1 more source

Long‐Acting Cabotegravir/Rilpivirine Reduces Immune‐Activation and ‐Senescence in People With HIV With CMV Co‐Infection

open access: yesImmunology, Volume 179, Issue 1, Page 138-148, September 2026.
This study investigates the impact of switching to long‐acting (LA) injectable cabotegravir and rilpivirine (CAB/RPV‐LA) on immune‐activation and ‐senescence in people with HIV (PWH). Thirty‐seven PWH switching to CAB/RPV‐LA and nine continuing oral ART were analysed over 72 weeks. LA therapy led to significant reductions in activation T and senescence
Mariasilvia Guardiani   +16 more
wiley   +1 more source

Integrated HIV and TB Services for the Management of Coinfection in West Africa: A Scoping Review of Strategies, Outcomes, Barriers and Enablers

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aim There is a concern about treatment outcomes for human immunodeficiency virus and tuberculosis infections in West Africa. This has led to a focus on the development of strategies for integrated care; however, data on the barriers and enablers of these strategies are limited.
Chris Mensah Nartey   +4 more
wiley   +1 more source

Unmasking Immune Reconstitution Inflammatory Syndrome (IRIS) : A report of five cases and review of the literature

open access: yesSultan Qaboos University Medical Journal, 2011
Immune reconstitution inflammatory syndromes (IRIS) in patients with acquired immune deficiency syndrome (AIDS) are characterised by atypical manifestations of opportunistic pathogens.
Abdullah Balkhair   +2 more
doaj  

From Oral Candidiasis to Candidemia: A Review of Superficial to Invasive Progression

open access: yesMicrobiologyOpen, Volume 15, Issue 4, August 2026.
Recent and limited evidence indicates that oral candidiasis can disseminate Candida albicans throughout the body, leading to invasive candidiasis, such as candidemia, a life‐threatening infection. Considering antifungal resistance and global outbreaks of emergent non‐albicans Candida and related yeasts, murine models help understand dissemination ...
Julia Robledo Jerez   +3 more
wiley   +1 more source

Unintended Consequences of Life‐Saving Pharmaceutical Innovations: How HAART Led to the Resurgence of Syphilis

open access: yesHealth Economics, Volume 35, Issue 7, Page 1118-1130, July 2026.
ABSTRACT Syphilis, a sexually transmitted infection that can lead to serious health complications, was almost eliminated in the United States by 2000. But since then, its incidence began to increase, recently reaching a 60‐year peak. We suggest that the introduction of the highly active antiretroviral therapy (HAART) drug regimen, which transformed HIV
David Beheshti   +2 more
wiley   +1 more source

Clinical features and treatment effect of HIV-associated immune thrombocytopenia—single center Ten-Years data summary

open access: yesPlatelets, 2023
Thrombocytopenia represents one of the most prevalent hematologic complications observed in patients infected with the human immunodeficiency virus (HIV). In this study, we sought to analyze the clinical characteristics and treatment outcomes of patients
YaXian Tan   +5 more
doaj   +1 more source

Dysregulated Metabolism in People Living With HIV in the Modern ART‐Era: A Systematic Review of Targeted Metabolomics Studies

open access: yesReviews in Medical Virology, Volume 36, Issue 4, July 2026.
ABSTRACT HIV remains a significant public health issue, with 1.3 million new infections and 630,000 deaths annually, and 40.8 million people living with HIV (PLHIV) globally in 2024. Although antiretroviral therapy (ART) suppresses viral replication, it does not eradicate the virus, and metabolic dysregulation persists despite treatment.
Levanco K. Asia   +4 more
wiley   +1 more source

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