Results 171 to 180 of about 9,446 (296)

Feedback control of excitability and high K+ induced epileptiform bursts in male rat hippocampal slices with a photocaged adenosine A1 receptor agonist

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 10, Page 2578-2591, May 2026.
Background and Purpose Adenosine is a potent regulator of neurotransmission and neuronal excitability, through activation of Gi coupled adenosine A1 receptors (A1Rs). Adenosine has gained interest as an anticonvulsant because of its endogenous involvement in ending seizure activity, but peripheral side effects require local application.
Erine Craey   +8 more
wiley   +1 more source

Disrupted immune senescence in early pregnancy is associated with recurrent pregnancy loss. [PDF]

open access: yesFront Immunol
Parvanov D   +8 more
europepmc   +1 more source

A Right‐Wing Populist Turn in the Conservative Party of Canada? Continuities and Ruptures Under the Leadership of Pierre Poilievre (2022–2025)

open access: yesCanadian Review of Sociology/Revue canadienne de sociologie, Volume 63, Issue 2, May 2026.
ABSTRACT Since his election as leader of the Conservative Party of Canada (CPC) in 2022, Pierre Poilievre has been associated with populism in media and political discourse, with implicit and explicit comparisons to Donald Trump. This article investigates the validity of such assessments by applying “complex” theories of populism, which conceptualize ...
Efe Peker, Emily Laxer, Rémi Vivès
wiley   +1 more source

Updates of the Status Quo of Situation‐Specific Theories (2015–2025)

open access: yesJournal of Nursing Scholarship, Volume 58, Issue 3, May 2026.
ABSTRACT Introduction Situation‐specific theories (SSTs) have emerged as an important approach for bridging the gap between nursing theory, research, and clinical practice. Unlike grand or middle‐range theories, SSTs address specific nursing phenomena within clearly defined populations or contexts.
Dongmi Kim, Eun‐Ok Im
wiley   +1 more source

Observed and Modeled Changes in Boundary‐Layer and Surface‐Level Actinic Flux Due To Wildfire Smoke Plumes in the California Central Valley in Summer 2018

open access: yesJournal of Geophysical Research: Atmospheres, Volume 131, Issue 8, 28 April 2026.
Abstract Wildfire smoke is increasingly degrading U.S. air quality via the emission and transport of pollutants. Smoke's direct role as a pollutant is well‐documented; however, smoke also affects pollutant concentration indirectly by changing the shortwave actinic flux necessary for photochemical reactions.
K. A. Corwin   +5 more
wiley   +1 more source

TGFβ1 Activates Lnc‐APUE to Promote Tumor Metastasis via the Alu Element‐Driven STAU1‐Mediated Decay of CDH1 mRNA

open access: yesAdvanced Science, Volume 13, Issue 20, 9 April 2026.
We delineate a TGFβ1/SMAD/lnc‐APUE/E‐cadherin axis wherein TGFβ1 signaling activates lnc‐APUE; lnc‐APUE subsequently downregulates E‐cadherin expression via Alu element‐driven STAU1‐mediated decay of CDH1 mRNA, thereby promoting tumor metastasis. Our findings reveal a novel regulatory function for lnc‐APUE within the SMD pathway, elucidate a distinct ...
Song‐Yang Li   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy