Advances in the pathophysiology and treatment of anaemia in multiple myeloma. [PDF]
Giuliani N +2 more
europepmc +1 more source
Circulating Tumor Cells in Multiple Myeloma: From Peripheral Clues to Central Insights
CTC offer a minimally invasive widow into systemic myeloma biology, overcoming the sampling bias of bone marrow biopsies. Their prognostic value at diagnosis, potential role in MRD monitoring, and ability to capture clonal evolution highlight them as actionable biomarkers for future precision medicine.
Benjamin Podvin +3 more
wiley +1 more source
Causal relevance of clonal haematopoiesis with cardiac disease and adverse remodelling: a Mendelian randomisation study. [PDF]
Morley AP +7 more
europepmc +1 more source
ABSTRACT In a large multicenter real‐world cohort, we aimed to evaluate outcomes of FLAG‐Ida salvage therapy for relapsed/refractory (R/R) acute myeloid leukemia (AML) and validated the SALFLAGE prognostic score. We analyzed 1079 adults with R/R AML treated across 112 PETHEMA institutions over 26 years (1998–2024), including patients with primary ...
Gaspar Aspas Requena +49 more
wiley +1 more source
Late Cytomegalovirus Infections After Allogeneic Hematopoietic Cell Transplant
ABSTRACT Graft versus host disease (GVHD) prophylaxis with posttransplant cyclophosphamide (ptCY) and cytomegalovirus (CMV) prophylaxis with letermovir have changed the clinical epidemiology of CMV infection. We studied the incidence, risk factors for, and outcomes of CMV infection after Day + 90 of allogeneic hematopoietic cell transplant (alloHCT ...
George L. Chen +15 more
wiley +1 more source
Evidence of jak2 val617phe positive essential thrombocythemia with splanchnic thrombosis during estroprogestinic treatment [PDF]
Colagrande, M +6 more
core
Management of Rapidly Progressive Symptomatic Splenomegaly with Associated Pancytopenia: A Rare Case of Splenic Hamartoma. [PDF]
Taprantzi D +5 more
europepmc +1 more source
The Role of the Gut Microbiota in Allogeneic Hematopoietic Cell Transplantation
ABSTRACT Allogeneic hematopoietic cell transplantation (allo‐HCT) is an effective treatment for patients with high‐risk hematologic malignancies. Over the last decade, gut microbiota composition during allo‐HCT has been associated with patients' outcomes.
Wenjing Hao +4 more
wiley +1 more source
Extensive extramedullary haematopoiesis in a patient with non-transfusion-dependent beta-thalassaemia. [PDF]
Distelmaier L, Kunz WG, Theurich S.
europepmc +1 more source
ABSTRACT Griscelli Syndrome Type 2 (GS2) is a rare autosomal recessive disorder caused by pathogenic mutations in the RAB27A gene. Typically, it is characterized by cutaneous hypopigmentation, immunodeficiency, with or without neurological abnormalities secondary to hemophagocytic lymphohistiocytosis (HLH). Without treatment, GS2 often results in fatal
Dzhoy Papingi +6 more
wiley +1 more source

