Results 231 to 240 of about 24,687 (303)

Outbreak of an infectious enteritis in western European hedgehogs (Erinaceus europaeus) in a rescue centre. [PDF]

Vet Res Commun
Cásero M, Serena J, Gomes-Gonçalves S, Mesquita JR, Seixas F, Coelho AC, Jota Baptista C.   +6 more
europepmc   +1 more source

The Critical Role of Fractionated Urine Glycosaminoglycans in the Evaluation of Mucopolysaccharidosis Type II in Four Unrelated Families

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Since 2015, Ann and Robert H. Lurie Children's Hospital has performed diagnostic testing for infants who screen positive for mucopolysaccharidosis type II (MPS II) on the Illinois newborn screen. Preliminary diagnostic testing includes measurement of plasma iduronate‐2‐sulfatase enzyme activity and urinary glycosaminoglycan analysis, followed ...
Carly A. Rasmussen, Monika Izdebski, Allison Paltzer, Rachel Hickey, Laura Pollard, Joshua Baker   +5 more
wiley   +1 more source

Clonal haematopoiesis of indeterminate potential is associated with progression of aortic valve stenosis. [PDF]

Eur J Heart Fail
Jamin RN, Shamekhi J, Zeus T, Mauri V, Al Zaidi M, Bartsch B, Ackerschott A, Nickenig G, Latz E, Zimmer S, Al-Kassou B.   +10 more
europepmc   +1 more source

Haematopoiesis in drug-induced agranulocytosis

Biomedicine & Pharmacotherapy, 1996
openaire   +2 more sources

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

Animal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty   +4 more
wiley   +1 more source

AK2-Deficient Mice Recapitulate Impaired Lymphopoiesis of Reticular Dysgenesis Patients, but Also Lack Erythropoiesis. [PDF]

Eur J Immunol
Waldmann R, Werner F, Tasdogan A, Maier FI, Kohlhofer U, Gonzalez-Menendez I, de Fend LQ, Puarr AK, Arkell RM, Enders A, Hoenig M, Schrezenmeier H, Fehling HJ, Schwarz K, Pannicke U.   +14 more
europepmc   +1 more source

Phenotypic profiling of pristane‐induced mimicking human systemic lupus erythematosus in Macaca fascicularis

Animal Models and Experimental Medicine, EarlyView.
Pristane (5 mL/kg) induced a robust systemic lupus erythematosus (SLE)‐like phenotype in Macaca fascicularis, marked by elevated antinuclear antibody (ANA) levels and systemic clinical, hematological, and biochemical changes. This model closely reflects human SLE and provides a translational platform for disease studies and therapeutic evaluation ...
Jonny Jonny, Soetojo Wirjopranoto, Chairul A. Nidom, I Ketut Sudiana, Terawan A. Putranto, Elisa D. Pratiwi, Tiza W. Mawaddah, Astria N. Nidom, Reviany V. Nidom, Setyarina Indrasari, Irma Y. Rosytania, Hiqmah Y. Yana, Sanindita Kusumastuti   +12 more
wiley   +1 more source

Placental iron utilisation in fetal growth restriction: alterations in mitochondrial haem synthesis and iron-sulphur cluster assembly pathways. [PDF]

J Physiol
Botha VB, Murray HC, Acharya S, Pringle KG, Smith R, Fisher JJ.   +5 more
europepmc   +1 more source

Complementary multi‐omics profiling of chronic thromboembolic pulmonary hypertension reveals immune cell alterations, epigenetic changes, and genetically supported candidate genes

Animal Models and Experimental Medicine, EarlyView.
This study presents an integrative multi‐omics framework to uncover the molecular mechanisms and potential biomarkers of chronic thromboembolic pulmonary hypertension (CTEPH). Anthropometric and biochemical data were correlated using canonical correlation analysis, revealing key cardiometabolic associations. Single‐cell RNA sequencing identified immune
Xiaopeng Liu, Xia Zheng, Yajun Zhang, Yinghui Fang, Yanan Zhen   +4 more
wiley   +1 more source

Pericytes and mesenchymal stromal cells converge toward pro-tumor phenotypes in the tumor microenvironment. [PDF]

Discov Oncol
La Spina E, Giallongo C, Longhitano L, Ferrigno J, Di Rosa G, Del Fabro V, Calvo D, Giallongo S, Romano D, Duminuco A, Palumbo GA, Galvano F, Li Volti G, Barbagallo IA, Tibullo D.   +14 more
europepmc   +1 more source