Results 71 to 80 of about 5,241 (198)

A importância do diagnóstico precoce na prevenção das anemias hereditárias The importance of early diagnosis in the prevention of hereditary anemias

Revista Brasileira de Hematologia e Hemoterapia, 2006
As anemias hereditárias, que englobam as hemoglobinopatias e talassemias são doenças determinadas geneticamente. Na maioria dos casos os heterozigotos são assintomáticos e desconhecem o defeito genético do qual são portadores.
Paulo R. Melo-Reis, Luiz M. M. Araújo, Karlla G. B. Dias-Penna, Mauro M. Mesquita, Frank S. Castro, Sérgio H. N. Costa   +5 more
doaj   +1 more source

Anaemia Among Mother–Child Dyads in India: Trends, Drivers, and Future Projections

Maternal &Child Nutrition, EarlyView.
ABSTRACT Anaemia among mothers and their children is a widespread public health challenge with profound consequences for individuals and societies. While anaemia has been studied separately in women and children, there remains a literature gap examining anaemia in mother‐child dyads, limiting insights on interventions that may simultaneously address ...
Sarang Pedgaonker, Trupti Meher, Monali Gupta, Suman Chakrabarti, Phuong Hong Nguyen, Shri Kant Singh, Laxmi Kant Dwivedi, Aditi, Samuel Scott   +8 more
wiley   +1 more source

Association of XmnI Polymorphism with Foetal Haemoglobin Level and Severity of Thalassaemia in Children: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: The North-eastern Region of India has been a rich reservoir of haemoglobinopathies and thalassaemias. Genetic modifiers, commonly known as ameliorating factors, like co-inheritance of α-thalassaemia, excess α genes, the presence of the XmnI
Aditi Baruah, Kumari Naina, Arpita Gogoi, Pritanu Deb Baruah, Gautam Hazarika, Lucretia Hazarika   +5 more
doaj   +1 more source

Massive fetomaternal hemorrhage and successful prevention of maternal RhD alloimmunization: A case report

Transfusion, EarlyView.
Abstract Background Massive fetomaternal hemorrhage can lead to significant fetal morbidity or mortality. RhD negative patients require appropriate treatment to prevent alloimmunization in subsequent pregnancies. Few cases with follow‐up into future pregnancies have been reported.
Sajjad Hassan, Angela Essa, Lauren Orr, Corina N. Schoen, Chester Andrzejewski   +4 more
wiley   +1 more source

A global survey of blood transfusion practices for patients with sickle cell disease

Transfusion, EarlyView.
Abstract Background Sickle cell disease (SCD) affects over 7 million people globally, with blood transfusion remaining a cornerstone of management. However, contemporary transfusion practices across diverse settings remain poorly characterized. We evaluated global transfusion practices for patients with SCD to identify gaps and inform resource ...
Jeremy W. Jacobs, Arwa Z. Al‐Riyami, Jeannie Callum, Meghan Delaney, David Daniel, Jenny White, Christopher Bocquet, Mohammed Farouk, Claude Tayou, Chinelo P. Onyenekwu, Kristina Prus, Divjot Singh Lamba, Julie Makani, Quentin Eichbaum, Luiz Amorim, Silvano Wendel, France Pirenne, Vernon Louw, Evan M. Bloch   +18 more
wiley   +1 more source

ITHANET: Information and database community portal for haemoglobinopathies

, 2017
Haemoglobinopathies are the commonest monogenic diseases, with millions of carriers and patients worldwide. Online resources for haemoglobinopathies are largely divided into specialised sites catering for patients, researchers and clinicians separately ...
Jacques Elion, Bin Alwi Zilfalil, Joanne Traeger-Synodinos, Celeste Bento, Marina Kleanthous, null null, Coralea Stephanou, Helen M Robinson, Petros Kountouris, Raj S Ramesar, Pavlos Fanis, Carsten W Lederer   +11 more
core   +1 more source

Quantification of haemoglobin A2 for mass screening of major haemoglobinopathies [PDF]

, 2023
Haemoglobinopathies are the most prevalent single-gene disorders and include a wide range of disorders most commonly thalassaemia and sickle cell disease (SCD).
Sant, Desiree
core  

Codocytosis in the Dog: 345 Cases (2020–2022)

Veterinary Clinical Pathology, EarlyView.
ABSTRACT Introduction Codocytes, or target cells, are a morphologic variation of erythrocytes characterized by increased membrane surface area relative to volume. In dogs, codocytosis is frequently noted on blood smear evaluation, but its clinical significance remains poorly understood. Objectives To characterize the clinical conditions associated with
Sarena M. Krojanker, Maria Jaramillo, Brad D. Cingolani, Floyd L. Williams Jr., Priscila B. S. Serpa, Andrew D. Woolcock   +5 more
wiley   +1 more source

Metabolic stimulation improves bioenergetics and haematologic indices of circulating erythrocytes from sickle cell mice

The Journal of Physiology, EarlyView.
Abstract figure legend Metabolic stimulation improves bioenergetics, redox state, hydration and hematologic indices of circulating erythrocytes from sickle cell mice. Retained mitochondria in circulating RBCs from sickle mice are a source of RBC ATP as mitochondria function (ETC, electron transport chain) inhibitors [rotenone, a mitochondrial complex I
Luis E. F. Almeida, Meghann L. Smith, Sayuri Kamimura, Sebastian Vogel, Zenaide M. N. Quezado   +4 more
wiley   +1 more source

Increasing the involvement of diverse populations in genomics-based health care—lessons from haemoglobinopathies [PDF]

, 2017
Integrating genomic medicine into health care delivery poses significant challenges to health professionals. To draw clinical benefit from genomic information, there is a need to build an evidence-based relationship between genotype and the physical ...
Helen M. Robinson, Robinson, HM
core   +1 more source