Results 121 to 130 of about 22,513 (247)

Long-term impact of COVID-19 on haemophilia: a multicenter study in Southwest China. [PDF]

open access: yesBMC Infect Dis
Cao C   +10 more
europepmc   +1 more source

100 Years of von Willebrand Disease (VWD): Comparison of Historical and Contemporary von Willebrand Factor (VWF) Activity Assays in the Laboratory Identification of VWD

open access: yesHaemophilia, EarlyView.
Abstract Introduction von Willebrand disease (VWD) is a prevalent bleeding disorder resulting from deficiencies and/or defects in von Willebrand factor (VWF). Accurately diagnosing VWD, particularly distinguishing between qualitative defects (types 2A, 2B, 2 M, and 2N) and quantitative defects (types 1 and 3), poses challenges that have significant ...
Emmanuel J. Favaloro   +4 more
wiley   +1 more source

Efficacy of Air‐Polishing in Managing Biofilm Formation in Patients Wearing Fixed Orthodontic Appliances: A Single‐Blind, Split‐Mouth, Randomised Controlled Trial

open access: yesInternational Journal of Dental Hygiene, EarlyView.
ABSTRACT Objectives To investigate the efficacy of air‐polishing in managing biofilm formation in patients wearing fixed orthodontic appliances. Methods This pilot study was designed as a single‐blind split‐mouth randomised controlled study. Twenty patients undergoing fixed orthodontic treatment were enrolled.
James Millar   +4 more
wiley   +1 more source

Advanced Molecular Analysis in Hemophilia A in a Single Step: Next Generation Sequencing (NGS) and Copy Number Variation (CNV) Analysis

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Hemophilia A, an X‐linked bleeding disorder caused by pathogenic variants in the F8 gene, requires precise genetic diagnosis for optimal management. Conventional stepwise sequence and copy number variation (CNV) analyses are time‐consuming and may leave some cases unresolved.
Enise Avci Durmusalioglu   +13 more
wiley   +1 more source

How I Investigate Bleeding Disorders of Unknown Cause: Current Diagnostic Pathways and Gaps in Laboratory Investigation

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Bleeding disorder of unknown cause (BDUC) constitutes the largest group of patients presenting with a mild‐to‐moderate bleeding tendency in tertiary care settings. Their clinical bleeding phenotype is characterized by mucocutaneous bleeding, as well as bleeding following surgical challenges or childbirth, and is associated with impaired health‐
Dino Mehic   +3 more
wiley   +1 more source

Testing for Non‐Severe Heritable Platelet Function Disorders

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Heritable platelet function disorders (HPFD) are a diverse group of bleeding disorders characterised by a primary qualitative defect in platelet function rather than platelet number. HPFD may be broadly categorised according to the severity of bleeding, with Glanzmann thrombasthenia and Bernard Soulier syndrome classically considered severe ...
Kate Burley   +3 more
wiley   +1 more source

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