Results 111 to 120 of about 22,513 (247)

Artificial Intelligence and Machine Learning in the Context of Hemophilia: A Scope Review

Haemophilia, EarlyView.
ABSTRACT Introduction Advances in hemophilia treatment have improved life expectancy, yet challenges remain in disease management, predicting clinical complications, and optimizing healthcare resources. Artificial intelligence (AI) and machine learning (ML) have emerged as promising tools to support clinical decision‐making and personalized care ...
Tatyane Oliveira Rebouças, André Cardoso Tavares, Antônio Diego Costa, Cícera Jamille Caldas Rodrigues, Lucilane Maria Sales da Silva   +4 more
wiley   +1 more source

Patient Perspectives in Haemophilia A: Unmet Needs of Individuals Receiving Factor and Non‐Factor Treatments

Haemophilia, EarlyView.
ABSTRACT Introduction There is limited qualitative published real‐world data on treatment patterns among people with severe haemophilia A (PwSHA), particularly those with unmet needs. Aim This qualitative study aimed to explore the impact of taking prophylactic extended half‐life factor VIII (EHL‐FVIII) or emicizumab on psychosocial and physical ...
Nana Kragh, Veruska Carboni, Duygu Bozkaya, Idaira Rodriguez‐Santana, Claudia Mighiu, Bethany Franks, Arnoud Plat, Randall Curtis   +7 more
wiley   +1 more source

Safety of Damoctocog Alfa Pegol in Patients With Severe Haemophilia A Aged 7 to <12 Years of Age: Pooled Data From PROTECT VIII Kids and Alfa‐PROTECT

Haemophilia, EarlyView.
Margareth C. Ozelo, Anthony K. C. Chan, Matteo Luciani, Monika Maas Enriquez, Claudia Tueckmantel, Maria Elisa Mancuso   +5 more
wiley   +1 more source

A Common Language for the Multidisciplinary Team: Point‐of‐Care Musculoskeletal Ultrasound in Modern Haemophilia Care

Haemophilia, EarlyView.
ABSTRACT The evolving haemophilia care landscape has evolved with personalised prophylaxis, new coagulation factor molecules, non‐replacement therapies, and gene therapy, leading to significantly reduced bleeding frequency and haemophilic arthropathy burden.
Hortensia De la Corte‐Rodriguez, María Teresa Álvarez‐Román, Mauro Davoli, Magnus Aspdahl, Christina Burgess, Karin Fijinvandraat, Roberta Gualtierotti, Cedric Hermans, Marko Marinić, Carlo Martinoli, Wolfgang Miesbach, Gianluigi Pasta, Michael Sigl‐Kraetzig, David Stephensen, Malin Svennefalk, Víctor Jiménez‐Yuste, the E.A.H.A.D. Joint Health Group   +16 more
wiley   +1 more source

Understanding Contact Risks of Pediatric Physical Activity: Video Analysis to Inform Decisions for Children at Risk of Bleeding Injuries

Haemophilia, EarlyView.
ABSTRACT Introduction Physical activity guidelines for children with inherited or acquired bleeding disorders are largely based on expert opinion rather than objective measures of injury exposure, making evidence‐based participation recommendations challenging.
Lauren Backstein, Ria Patel, Mona Elmikaty, Brooklyn Westlake, Sarah Sbeiti, Leonardo R. Brandão, Robert Klaassen, Allison Clouthier, Chris Joslin, Ryan Graham, Patricia E. Longmuir   +10 more
wiley   +1 more source

Generational Differences in Illness‐Related Uncertainty Among Haemophilia Carriers: A Qualitative Study Using Mishel's Uncertainty in Illness Theory

Haemophilia, EarlyView.
ABSTRACT Aim Haemophilia carriers (HCs) have historically been regarded as asymptomatic or only mildly affected, resulting in under‐recognition of bleeding symptoms and unmet healthcare needs. Although advances in healthcare and access to information have changed the experience of haemophilia, little is known about how illness‐related uncertainty ...
Tomie Fujii, Teruhisa Fujii, Teiji Uchino   +2 more
wiley   +1 more source

Knowledge on the Haemophilia Care Among Healthcare Providers in Tanzania: A Multicenter Cross-Sectional Study. [PDF]

J Blood Med
Rwezaula SS, Mtoba SD, Mahlangu J, Mwakigonja AR, Iranloye B, Akinloye O.   +5 more
europepmc   +1 more source

Population Pharmacokinetics of Plasma‑Derived Factor X Using Clotting and Chromogenic Assays: A WAPPS‑Hemo Model

Haemophilia, EarlyView.
ABSTRACT Background Hereditary factor X (FX) deficiency is a rare autosomal recessive bleeding disorder for which individualized pharmacokinetic (PK) assessment can support optimized prophylactic management. The WAPPS‐Hemo platform enables population pharmacokinetic (PopPK) individualized PK predictions based on sparse sampling.
Dagmar M. Hajducek, Pierre Chelle, Manuela Scarpellini, Andrea Edginton, Alfonso Iorio   +4 more
wiley   +1 more source

Haemophilia A in a Female German Shepherd With Homozygosity for the FVIII p.C567Y Variant in Exon 11 of the F8 Gene. [PDF]

Anim Genet
Brenig B, Pach S.
europepmc   +1 more source

Perioperative Management in Persons With Haemophilia on Rebalancing Therapies: A Narrative Review

Haemophilia, EarlyView.
ABSTRACT Introduction Perioperative management in haemophilia often requires on‐demand use of clotting factor concentrates (CFC) and/or bypassing agents. Rebalancing agents (fitusiran, concizumab, marstacimab) offer a novel approach to prophylaxis by modulating endogenous anticoagulant pathways to restore haemostatic balance.
Amanda M. Henderson, Roy Khalife, Kelsey Uminski   +2 more
wiley   +1 more source