Results 41 to 50 of about 21,171,014 (388)

The Second Team Haemophilia Education Meeting, 2016, Frankfurt, Germany [PDF]

, 2017
The first Team Haemophilia Education (THE) Meeting was held on 7-8 May 2015 in Amsterdam, The Netherlands. It aimed to promote the optimal care of patients with haemophilia through education of the multidisciplinary treatment team.
Berntorp, E, Blatný, J, Chambost, H, d'Oiron, R, Dargaud, Y, Dettoraki, A, Doria, AS, Farrell, A, Halimeh, S, Hart, D, Holme, PA, Kaczmarek, R, Laane, E, Lobet, S, Maia, R, Mancuso, ME, Mantovani, L, McLaughlin, P, Nanayakkara, L, Perry, D, Petrini, P, Pollard, D, Raza, S, Sannié, T, Taylor, S, van den Berg, M   +25 more
core   +1 more source

Global measurement of coagulation in plasma from normal and haemophilia dogs using a novel modified thrombin generation test - Demonstrated in vitro and ex vivo. [PDF]

PLoS ONE, 2017
Canine models of severe haemophilia resemble their human equivalents both regarding clinical bleeding phenotype and response to treatment. Therefore pre-clinical studies in haemophilia dogs have allowed researchers to make valuable translational ...
Daniel Elenius Madsen, Timothy C Nichols, Elizabeth P Merricks, Emily K Waters, Bo Wiinberg   +4 more
doaj   +1 more source

Recombinant factorVIII Fc fusion protein for the prevention and treatment of bleeding in children with severe hemophilia A [PDF]

, 2015
This work was supported by funding from Biogen, including funding for the editorial and writing support in the the development of this ...
Allen, G, Barnes, C, Cristiano, LM, Gambino, G, Kulkarni, R, Liesner, R, Mahlangu, J, Neelakantan, S, Nolan, B, Pasi, J, Pierce, GF, Young, G   +11 more
core   +1 more source

Cost‐effectiveness of emicizumab vs bypassing agents in the prevention of bleeding episodes in haemophilia A patients with anti‐FVIII inhibitors in France

Haemophilia, 2020
The development of an anti‐FVIII inhibitor is the most serious complication of haemophilia A occurring in up to 30% of severe haemophilic patients.
B. Polack, M. Trossaërt, M. Cousin, S. Baffert, A. Pruvot, C. Godard   +5 more
semanticscholar   +1 more source

Impact of Functional Disability on Quality of Life in Patients with Haemophilia: An Observational Study [PDF]

Journal of Clinical and Diagnostic Research, 2021
Introduction: Haemophilia is a disease characterised by multiple episodes of spontaneous as well as traumatic bleeding leading to joint pains, joint damage.
Ashish Kavi, Mrinal Joshi, Surbhi Mittal, Poonam Banthi   +3 more
doaj   +1 more source

Perinatal Gene Transfer to the Liver [PDF]

, 2011
The liver acts as a host to many functions hence raising the possibility that any one may be compromised by a single gene defect. Inherited or de novo mutations in these genes may result in relatively mild diseases or be so devastating that death within
Buckley, SM, Chan, JK, Howe, SJ, McKay, TR, Rahim, AA, Waddington, SN, Ward, NJ   +6 more
core   +1 more source

Haematology clinic: Haemophilia A

Hematology, 2014
Haemophilia A is a rare inherited bleeding disorder resulting from the deficiency of factor VIII (FVIII), an essential component of the intrinsic pathway of blood coagulation.
Pier Mannuccio, Mannucci, Massimo, Franchini   +1 more
openaire   +2 more sources

Disease burden and remaining unmet need in patients with haemophilia A treated with primary prophylaxis

Haemophilia, 2020
There is evidence that people with haemophilia A still experience morbidity and functional limitation due to joint damage despite prophylaxis. This study aimed to compare their quality of life and work‐related function with that of the general population
Sonia O’Hara, F. Castro, James M. Black, S. Chaplin, L. Ruiz, R. Hampton, C. S. Sima, J. O’Hara   +7 more
semanticscholar   +1 more source

Three-Decade Successive Establishment of Care for Women/Girls from Families with Haemophilia

The Application of Clinical Genetics, 2022
Ampaiwan Chuansumrit,1 Werasak Sasanakul,1 Nongnuch Sirachainan,1 Suttikarn Santiwatana,1 Praguywan Kadegasem,1 Pakawan Wongwerawattanakoon,2 Noppawan Tungbubpha,1 Juthamard Chantaraamporn1 1Department of Pediatrics, Faculty of Medicine, Ramathibodi ...
Chuansumrit A, Sasanakul W, Sirachainan N, Santiwatana S, Kadegasem P, Wongwerawattanakoon P, Tungbubpha N, Chantaraamporn J   +7 more
doaj  

Molecular Profiling of FIX (FACTOR 9) Gene of Hemophilia B in Karnataka

BLDE University Journal of Health Sciences, 2020
Introduction: Haemophilia is one of the “Bleeder Disorder” that causes abnormal bleeding or poor blood clotting. It occurs due to the defect in the clotting factors even in their functions and in some cases structures are altered.
Sujayendra Kulkarni, Rajat Hegde, Smita Hegde, Suyamindra Kulkarni, Sanjeev Kolagi, Pramod Gai, Rudragouda Bulagouda   +6 more
doaj   +1 more source