Changing patterns of invasive meningococcal disease and future immunization strategies
Human Vaccines & Immunotherapeutics, 2023 Invasive meningococcal disease (IMD) is a life-threatening disease caused by Neisseria meningitidis and has high mortality rates. Survivors often exhibit long-term sequelae and reduced life expectancy. Disease incidence is highest in infants and toddlers,
Muhamed-Kheir Taha +2 more
doaj +1 more source
Mandatory vaccinations in European countries, undocumented information, false news and the impact on vaccination uptake: the position of the Italian pediatric society. [PDF]
, 2018 BACKGROUND: High rates of vaccination coverage are important in preventing infectious diseases. Enforcing mandatory vaccinations is one of the strategies that some Countries adopted to protect the community when vaccination coverage is not satisfactory ...
Bozzola E +5 more
core +2 more sources
Conjugate Haemophilus influenzae type b vaccines for sickle cell disease. [PDF]
, 2016 BACKGROUND: People affected with sickle cell disease are at high risk of infection from Haemophilus influenzae type b. Before the implementation of Haemophilus influenzae type b conjugate vaccination in high-income countries, this was responsible for a ...
Allali, Slimane +4 more
core +2 more sources
Phosphocholine-Modified Lipooligosaccharides of Haemophilus influenzae Inhibit ATP-Induced IL-1beta Release by Pulmonary Epithelial Cells [PDF]
, 2018 Phosphocholine-modified bacterial cell wall components are virulence factors enabling immune evasion and permanent colonization of the mammalian host, by mechanisms that are poorly understood.
Grau, Veronika +11 more
core +1 more source
Journal of Microbiology, Immunology and Infection, 2021 Background/purpose: This study aimed to investigate the clinical characteristics and outcomes of bacteremia caused by Haemophilus and Aggregatibacter species in patients who were treated at a medical center between 2006 and 2018. Methods: Haemophilus and
Ying-Chun Chien +4 more
doaj +1 more source
Invasive Haemophilus influenzae Disease in Adults ≥65 Years, United States, 2011. [PDF]
, 2014 BackgroundSince the introduction of the Haemophilus influenzae serotype b vaccine, H influenzae epidemiology has shifted. In the United States, the largest burden of disease is now in adults aged ≥65 years.
Bennett, Nancy +15 more
core +1 more source
Phase I, randomized, observer-blind, placebo-controlled studies to evaluate the safety, reactogenicity and immunogenicity of an investigational non-typeable Haemophilus influenzae (NTHi) protein vaccine in adults [PDF]
, 2016 Background: Non-typeable Haemophilus influenzae (NTHi) is a major cause of various respiratory diseases. The development of an effective vaccine against NTHi mandates new approaches beyond conjugated vaccines as this opportunistic bacterium is non ...
Aris, Emmanuel +7 more
core +2 more sources
Nod1 signaling overcomes resistance of S. pneumoniae to opsonophagocytic killing [PDF]
, 2007 Airway infection by the Gram-positive pathogen Streptococcus pneumoniae (Sp) leads to recruitment of neutrophils but limited bacterial killing by these cells.
Clarke, Thomas B. +6 more
core +3 more sources
Epidemiology of Invasive Haemophilus influenzae Disease, Europe, 2007–2014
Emerging Infectious Diseases, 2017 We describe the epidemiology of invasive Haemophilus influenzae disease during 2007–2014 in 12 European countries and assess overall H. influenzae disease trends by serotype and patient age. Mean annual notification rate was 0.6 cases/100,000 population,
R. Whittaker +5 more
semanticscholar +1 more source
Scientific Reports, 2019 The demographics and comorbidities of patients with community acquired pneumonia (CAP) vary enormously but stratified treatment is difficult because aetiological studies have failed to comprehensively identify the pathogens.
D. Wootton +15 more
semanticscholar +1 more source