Results 51 to 60 of about 206,287 (344)

The Role of α-Defensins 1–3 in Antimicrobial Protection Forming in Children with Recurrent Bronchitis Caused by Bacteria of the Genus Haemophilus

open access: yesZdorovʹe Rebenka, 2013
The level of α-defensins 1–3 (HNP 1–3) has been analyzed in the blood plasma of children with recurrent bronchitis caused by bacteria of the genus Haemophilus.
G.O. Lezhenko   +3 more
doaj   +1 more source

MGM as a Large‐Scale Pretrained Foundation Model for Microbiome Analyses in Diverse Contexts

open access: yesAdvanced Science, EarlyView.
We present the Microbial General Model (MGM), a transformer‐based foundation model pretrained on over 260,000 microbiome samples. MGM learns contextualized microbial representations via self‐supervised language modeling, enabling robust transfer learning, cross‐regional generalization, keystone taxa discovery, and prompt‐guided generation of realistic,
Haohong Zhang   +5 more
wiley   +1 more source

The Lung Immune Response to Nontypeable Haemophilus influenzae (Lung Immunity to NTHi)

open access: yesJournal of Immunological Research, 2015
Haemophilus influenzae is divided into typeable or nontypeable strains based on the presence or absence of a polysaccharide capsule. The typeable strains (such as type b) are an important cause of systemic infection, whilst the nontypeable strains ...
P. King, Roleen Sharma
semanticscholar   +1 more source

Droplet Digital CRISPR for Nucleic Acid Detection

open access: yesAdvanced Science, EarlyView.
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang   +4 more
wiley   +1 more source

Fluctuations in serogroup B meningococcal vaccine antigens prior to routine MenB vaccination in France

open access: yesCommunications Medicine
Background Invasive meningococcal disease (IMD) of serogroup B is preventable by protein-based vaccines targeting one (Bivalent rLP2086 vaccine) or several variable proteins (4CMenB vaccine) at the bacterial surface.
Michaël Falguières   +5 more
doaj   +1 more source

Haemophilus influenzae: using comparative genomics to accurately identify a highly recombinogenic human pathogen

open access: yesBMC Genomics, 2015
Haemophilus influenzae is an opportunistic bacterial pathogen that exclusively colonises humans and is associated with both acute and chronic disease. Despite its clinical significance, accurate identification of H. influenzae is a non-trivial endeavour.
E. Price   +9 more
semanticscholar   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari   +5 more
wiley   +1 more source

Nasal Bacterial Microbiome: Probing a Healthy Porcine Family [PDF]

open access: yes, 2011
Upper respiratory tract (URT) infection caused the leading and devastating diseases in pigs. It was believed that the normal microbiome of URT plays a vital role in health and disease development.
Huanchun Chen, Min Yue, Weicheng Bei
core   +2 more sources

A review of the role of Haemophilus influenzae in community-acquired pneumonia

open access: yesPneumonia, 2015
In an era when Haemophilus influenzae type b (Hib) conjugate vaccine is widely used, the incidence of Hib as a cause of community-acquired pneumonia (CAP) has dramatcally declined. Non-typeable H.
M. Slack
semanticscholar   +1 more source

Dietary Baicalin Supplementation Can Enhance the Growth Performance of Weaned Piglets and Maintain the Intestinal Barrier Integrity

open access: yesAnimal Research and One Health, EarlyView.
This research innovatively illustrates baicalin’s multifaceted mechanisms in enhancing piglets’ intestinal health: modulating bile acid metabolism via probiotics, reinforcing tight junction proteins (ZO‐1/claudin), suppressing TLR4/NF‐κB‐mediated inflammation, whereas promoting growth and reducing diarrhea.
Yuhui Gao   +6 more
wiley   +1 more source

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