Results 71 to 80 of about 149,978 (325)

Cefuroxime axetil dosing regimens and probability of target attainment in adults and children

British Journal of Clinical Pharmacology, EarlyView.
Aims Cefuroxime axetil exists in several dosage forms for oral administration, and is indicated for treatment of respiratory, genitourinary, skin and soft tissue infections. Evolving patterns of bacterial susceptibility, expressed as increasing minimum inhibitory concentrations (MICs), warrant monitoring of antibiotic efficacy.
Sven C. van Dijkman, Praveen Kamble, Jerzy A. Kowalski, Oscar Della Pasqua   +3 more
wiley   +1 more source

The first reported case of possible Haemophilus influenzae type b vaccine failure from Kuwait and literature-review

Journal of Infection and Public Health, 2014
Summary: A 17-month-old vaccinated Kuwaiti boy presented with meningitis. The Haemophilus influenzae type b (Hib) capsular antigen was detected in his blood, CSF and urine. The microorganism failed to grow in culture.
Prashant Purohit, Ina’am Ahmad Al-Obaid, Nehad Gamal Al-Deen Omar   +2 more
doaj   +1 more source

Inhibitors of Bacterial \u3cem\u3eN\u3c/em\u3e-succinyl-L,L-diaminopimelic Acid Desuccinylase (DapE) and Demonstration of in vitro Antimicrobial Activity [PDF]

, 2009
The dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE) is a critical bacterial enzyme for the construction of the bacterial cell wall. A screen biased toward compounds containing zinc-binding groups (ZBG’s) including thiols, carboxylic ...
Armoush, Nicola, Becker, Daniel P., Gillner, Danuta, Holz, Richard C.   +3 more
core   +1 more source

Cephalosporin-3’-diazeniumdiolate NO-donor prodrug PYRRO-C3D enhances azithromycin susceptibility of non-typeable Haemophilus influenzae biofilms [PDF]

, 2016
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Objectives: PYRRO-C3D is a cephalosporin-3-diazeniumdiolate nitric oxide (NO)-donor prodrug designed to ...
Allan, Raymond N., Coles, J., Collins, S. A., Connett, G., Faust, S. N., Feelisch, M., Hall-Stoodley, L., Halladay, G. D., Jackson, C. L., Kelso, M. J., Lucas, J. S. A., Rineh, A., Walker, W. T., Webb, J. S., Yepuri, N. R.   +14 more
core   +2 more sources

Lower airway colonization and inflammatory response in COPD: a focus on Haemophilus influenzae

International Journal of COPD, 2014
Bacterial infection of the lower respiratory tract in chronic obstructive pulmonary disease (COPD) patients is common both in stable patients and during acute exacerbations.
L. Finney, A. Ritchie, Elizabeth Pollard, S. Johnston, P. Mallia   +4 more
semanticscholar   +1 more source

Promising Prodiginins Biological Activities

Chemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto, Melisa E. Gantner, Boris E. Rodenak‐Kladniew, Santiago Rodriguez, María L. Cuestas, Alan Talevi, Guillermo R. Castro   +6 more
wiley   +1 more source

Selection for Phase Variation of LOS Biosynthetic Genes Frequently Occurs in Progression of Non-Typeable Haemophilus influenzae Infection from the Nasopharynx to the Middle Ear of Human Patients

PLoS ONE, 2014
Surface structures in Haemophilus influenzae are subject to rapid ON/OFF switching of expression, a process termed phase variation. We analyse tetranucleotide repeats controlling phase variation in lipo-oligosaccharide (LOS) genes of H.
Kate L. Fox, John M. Atack, Y. Srikhanta, Anja Eckert, L. Novotny, L. Bakaletz, M. Jennings   +6 more
semanticscholar   +1 more source

Anti‐Inflammatory Effects of Flavonoids in Otitis Media: A Systematic Review of Pre‐Clinical Evidence

Food Frontiers, EarlyView.
Otitis media (OM) is a middle ear infection driven by chronic inflammation, leading to tissue damage and complications such as cholesteatoma. Flavonoids, a class of polyphenols with anti‐inflammatory properties, suppress key inflammatory mediators, reducing neutrophilic infiltration and mucosal thickening. These findings suggest flavonoids as potential
Madiha Ajaz, Ayesha Zahid, Hazrat Ismail, Misbah Ajaz   +3 more
wiley   +1 more source

Production of Specific Fragments of {varphi}X174 Replicative Form DNA by a Restriction Enzyme from Haemophilus parainfluenzae, Endonuclease HP [PDF]

, 1973
A restriction endonuclease from Haemophilus parainfluenzae degrades {varphi}X174 replicative form DNA into eight specific fragments, ranging from 1,700 to 150 base pairs and terminated specifically by deoxycytidylic ...
Johnson, Paul H., Lee, Amy Shiu, Sinsheimer, Robert L.   +2 more
core  

Correlation property of length sequences based on global structure of complete genome [PDF]

, 2000
This paper considers three kinds of length sequences of the complete genome. Detrended fluctuation analysis, spectral analysis, and the mean distance spanned within time $L$ are used to discuss the correlation property of these sequences.
A. Arneodo, A. K. Mohanty, A. L. Goldberger, A. Provata, B. Lewin, B.-L. Hao, Bin Wang, C. A. Chatzidimitriou-Dreismann, C. K. Peng, C. K. Peng, C. M. Fraser, E. Simoen, F. N. H. Robinson, H. E. Stanley, H. Herzel, J. Maddox, L. Luo, M. de Sousa Vieira, N. Iwabe, P. Allegrini, R. D. Remington, R. H. Shumway, R. M. Dunki, R. M. Dunki, R. Voss, R. Voss, S. Karlin, S. Nee, S. V. Buldyrev, V. V. Anh, V. V. Prabhu, W. Li, W. Li, Z.-G. Yu, Z.-G. Yu, Z.-G. Yu, Zu-Guo Yu   +36 more
core   +4 more sources