Results 81 to 90 of about 154,412 (312)
Long Term Impact of Conjugate Vaccines on Haemophilus influenzae Meningitis: Narrative Review [PDF]
, 2021 Mary Slack
openalex +1 more source
PLoS ONE, 2014 Surface structures in Haemophilus influenzae are subject to rapid ON/OFF switching of expression, a process termed phase variation. We analyse tetranucleotide repeats controlling phase variation in lipo-oligosaccharide (LOS) genes of H.
Kate L. Fox +6 more
semanticscholar +1 more source
Metabolic versatility in Haemophilus influenzae: a metabolomic and genomic analysis
Frontiers in Microbiology, 2014 Haemophilus influenzae is a host adapted human pathogen known to contribute to a variety of acute and chronic diseases of the upper and lower respiratory tract as well as the middle ear.
Dk Seti Maimonah Pg Othman +3 more
semanticscholar +1 more source
Who Will Protect the Children?
Annals of the Child Neurology Society, EarlyView.
William D. Graf, Leon G. Epstein
wiley +1 more source
Clinical &Experimental Ophthalmology, EarlyView.ABSTRACT Background Endophthalmitis requiring multiple ocular tissue sampling for microbiological testing is uncommon and has not been previously studied. This study aims to analyse cases with at least two ocular tissue samplings and testing of different ocular samples against culture yields. Methods A 27‐year prospective observational study using data
Pravena Kumaran +5 more
wiley +1 more source
Clinical Genetics, EarlyView.CT scan image of a 17‐year‐old female with primary ciliary dyskinesia (PCD) showing dextrocardia and bilateral bronchiectasis. The study describes genetic mutations affecting patients with PCD in Qatar and the corresponding clinical phenotype of affected patients.
Atqah AbdulWahab +7 more
wiley +1 more source
Infections in Chronic Lymphocytic Leukemia: Evolving Risks and Prevention Strategies
European Journal of Haematology, EarlyView.ABSTRACT Infections remain a leading cause of morbidity and mortality in patients with chronic lymphocytic leukemia (CLL), reflecting both intrinsic immune dysfunction and therapy‐related immunosuppression. The pathogenesis of immunodeficiency in CLL is multifactorial: neoplastic B cells impair humoral immunity, T cells are functionally exhausted, and ...
Enrica Antonia Martino +10 more
wiley +1 more source
From the microbiome to the central nervous system, an update on the epidemiology and pathogenesis of bacterial meningitis in childhood [version 1; referees: 3 approved] [PDF]
, 2017 In the past century, advances in antibiotics and vaccination have dramatically altered the incidence and clinical outcomes of bacterial meningitis. We review the shifting epidemiology of meningitis in children, including after the implementation of ...
Janowski, Andrew B, Newland, Jason G
core +3 more sources
Molecular basis of antibiotic sensing by the TetR family regulator CecR – a structural perspective
The FEBS Journal, EarlyView.Escherichia coli CecR, a member of the TetR family regulators, senses selected antibiotics and activates the expression of a putative drug efflux pump. Although present in many pathogenic Enterobacteriales strains, CecR remains poorly characterized. We present the first CecR crystal structure, which reveals a unique tunnel‐like ligand‐binding cavity ...
Agnieszka J. Pietrzyk‐Brzezinska +5 more
wiley +1 more source
Molecular epidemiology of nontypeable haemophilus influenzae causing community-acquired pneumonia in adults [PDF]
, 2016 Nontypeable Haemophilus influenzae (NTHi) is an opportunistic pathogen which causes a variety of respiratory infections. The objectives of the study were to determine its antimicrobial susceptibility, to characterize the b-lactam resistance, and to ...
Ardanuy Tisaire, María Carmen +7 more
core +1 more source