Results 21 to 30 of about 611,282 (250)

"Getting to the roots" : a critical examination into the social construction of hair amongst Coloured women living in Cape Town. [PDF]

open access: yes, 2013
Includes bibliographical references.The purpose of this study is to explore how the social construction of head-hair impacts the lived experiences of a small group of 'Coloured' women living in Cape Town.
Richardson, Denisha
core   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Spironolactone versus Bicalutamide for Female Pattern Hair Loss: A 24-Month Unicenter Retrospective Comparative Study of Effectiveness and Safety

open access: yesDermatology and Therapy
Introduction Female pattern hair loss (FPHL) is a chronic, progressive condition that affects quality of life. Off-label systemic antiandrogens are increasingly used, but comparative data remain limited.
Rocío Gil-Redondo   +9 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Protective effect of Korean Red Ginseng against chemotherapeutic drug-induced premature catagen development assessed with human hair follicle organ culture model

open access: yesJournal of Ginseng Research, 2016
Background: Chemotherapy-induced alopecia (CIA) is one of the most distressing side effects for patients undergoing chemotherapy. This study evaluated the protective effect of Korean Red Ginseng (KRG) on CIA in a well-established in vitro human hair ...
Dong In Keum   +3 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Clinical Signs of Hair Damage

open access: yes, 2015
The environment causes daily damage to the hair shaft that cannot be repaired and is more evident in the distal part of long hair. Clinical signs of hair damage depend on type of damage and severity of damage.
Marsh, Jennifer   +5 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

A Disease in Disguise-A Case Report on an Atypical Presentation of Bowen's disease

open access: yesNepal Journal of Dermatology, Venereology & Leprology
Bowen’s disease (BD) is a rare premalignant condition. The etiology of Bowen’s disease is multifactorial. Classically, it presents as a well‑demarcated erythematous plaque, predominantly in photo-exposed areas.
E.P Raj Kirit   +3 more
doaj   +3 more sources

Case Report: Long-lasting adrenal insufficiency following successful osilodrostat therapy with subsequent recurrence of Cushing’s syndrome

open access: yesFrontiers in Endocrinology
Osilodrostat is an effective steroidogenesis inhibitor used in the treatment of Cushing’s syndrome (CS). One of the clinically significant adverse events associated with this therapy is adrenal insufficiency (AI).
Wiktoria Suchy   +5 more
doaj   +1 more source

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