Results 31 to 40 of about 472,883 (297)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Treatment of wounds after operations on the anal canal and perineum

Амбулаторная хирургия
There are alimited number of publications in both domestic and foreign literature on the treatment of wounds in patients after anal canal and perineal surgery.
M. V. Abritsova, N. R. Torchua
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Premature Graying of Hair

Nepal Journal of Dermatology, Venereology & Leprology
Premature Graying of hair (PGH) is a common and psychologically distressing condition of the hair. It is seen as being aggravated by various triggering factors. But the pathogenesis and the treatment options are still under study and limited.
Shreya Bastakoti, Timothy Upashna
doaj   +3 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Olfactory receptor OR2AT4 regulates human hair growth

Nature Communications, 2018
Increasing evidence suggest that olfactory receptors can carry additional functions besides olfaction. Here, Chéret et al. show that stimulation of the olfactory receptor ORT2A4 by the odorant Sandalore® stimulates growth of human scalp hair follicles ex
Jérémy Chéret, Marta Bertolini, Leslie Ponce, Janin Lehmann, Teresa Tsai, Majid Alam, Hanns Hatt, Ralf Paus   +7 more
doaj   +1 more source

COVID-19 Infection: Impact on Hair

Indian Journal of Plastic Surgery, 2021
With a practice dedicated to hair restoration and hair loss management, the authors have seen a large number of patients presenting with increased hair fall in the last 18 months.
Sandeep Suresh Sattur, Indu Sandeep Sattur   +1 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Case Report: Continuous block-and-replace strategy with osilodrostat in a patient with cyclic Cushing’s syndrome

Frontiers in Endocrinology
Evidence on cyclic Cushing’s syndrome (cCS) is limited. Due to its rarity and diagnostic challenges, some patients remain undiagnosed and experience life-threatening episodes of hyper- and hypocortisolemia.
Wiktoria Suchy, Mari Minasyan, Aleksandra Gamrat-Żmuda, Alicja Hubalewska-Dydejczyk, Aleksandra Gilis-Januszewska   +4 more
doaj   +1 more source

The Impact of Shampoo Wash Frequency on Scalp and Hair Conditions [PDF]

, 2021
Supriya Punyani, Antonellá Tosti, Maria Hordinsky, Dawn J. Yeomans, James R. Schwartz   +4 more
openalex   +1 more source