Results 31 to 40 of about 611,282 (250)

Pharmacological Management of Pattern Hair Loss

Indian Journal of Plastic Surgery, 2021
Pattern hair loss (PHL) is a condition that worsens with time and the only way it can be slowed down is with pharmacological intervention. Pharmacological treatments for PHL, from an evidenced-based perspective with respect to safety and efficacy, are ...
Sandeep Suresh Sattur, Indu Sandeep Sattur   +1 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Premature Graying of Hair

Nepal Journal of Dermatology, Venereology & Leprology
Premature Graying of hair (PGH) is a common and psychologically distressing condition of the hair. It is seen as being aggravated by various triggering factors. But the pathogenesis and the treatment options are still under study and limited.
Shreya Bastakoti, Timothy Upashna
doaj   +3 more sources

Development of a high-throughput UHPLC–MS/MS multi-method for the analysis of mycotoxins in plant-based milk alternatives as the basis for risk assessment

Frontiers in Nutrition
Plant-based alternatives to animal-based foods represent a rapidly growing market, as more and more consumers are willing to include these products into their daily diets. One particular segment is plant-based milk alternatives (PBMAs). Environmental and
Fabian Dick, Maximilian Schuster, Sarah Schneidemann-Bostelmann, Stefan Asam, Michael Rychlik   +4 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Treatment of wounds after operations on the anal canal and perineum

Амбулаторная хирургия
There are alimited number of publications in both domestic and foreign literature on the treatment of wounds in patients after anal canal and perineal surgery.
M. V. Abritsova, N. R. Torchua
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Case Report: Continuous block-and-replace strategy with osilodrostat in a patient with cyclic Cushing’s syndrome

Frontiers in Endocrinology
Evidence on cyclic Cushing’s syndrome (cCS) is limited. Due to its rarity and diagnostic challenges, some patients remain undiagnosed and experience life-threatening episodes of hyper- and hypocortisolemia.
Wiktoria Suchy, Mari Minasyan, Aleksandra Gamrat-Żmuda, Alicja Hubalewska-Dydejczyk, Aleksandra Gilis-Januszewska   +4 more
doaj   +1 more source

Hair Density Reduction

, 2015
Hair loss is always very distressful and considerably impacts the patient’s quality of life. Patients may complain of increased shedding, hair thinning, or both.
Marsh, Jennifer, Gray, John, Tosti, Antonella, Antonella Tosti, John Gray, Jennifer Marsh   +5 more
core   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source