Results 201 to 210 of about 50,414 (231)

Compound synapses within the GABAergic innervation of the auditory inner hair cells in the adolescent mouse

The Journal of Comparative Neurology, 1997
Ultrastructural investigation of the gamma-aminobutyric acid (GABA) component of the inner spiral bundle in adolescent mice revealed a pathway of glutamic acid decarboxylase (GAD)-positive and -negative fibers and vesiculated endings that contact inner hair cells and their afferents through a complex of axosomatic and axodendritic synapses ...
H. Sobkowicz, S. Slapnick, L. Nitecka, B. August   +3 more
semanticscholar   +4 more sources

A revised model of the inner-hair cell and auditory-nerve complex

The Journal of the Acoustical Society of America, 2002
A revised computational model of the inner-hair cell (IHC) and auditory-nerve (AN) complex is presented and evaluated. Building on previous models, the algorithm is intended as a component for use in more comprehensive models of the auditory periphery. It combines smaller components that aim to be faithful to physiology in so far as is practicable and ...
Lowel P. O’Mard, Christian J. Sumner, Enrique A. Lopez-Poveda, Ray Meddis   +3 more
openaire   +3 more sources

Simulation of the efficiency of inner hair cell secretion in the auditory pathway

2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2019
Sound coding involves several stages of processing along the auditory path. Specifically, the Inner Hair Cells (IHC) act as sensory receptors and transduce acoustic information -frequency, intensity and duration of the stimulus- into neuronal signals. In this work, a stochastic model was implemented to achieve a better understanding of the IHC-auditory
Amparo Gil, Norma Castañeda-Villa, J. Soto, Virginia González-Vélez   +3 more
openaire   +2 more sources

Analysis of models for the synapse between the inner hair cell and the auditory nerve

The Journal of the Acoustical Society of America, 2005
A general mathematical approach was proposed to study phenomenological models of the inner-hair-cell and auditory-nerve (AN) synapse complex. Two models (Meddis, J. Acoust. Soc. Am. 79(3), 702–711 (1986); Westerman and Smith, J. Acoust. Soc. Am. 83(6), 2266–2276 (1988)) were studied using this unified approach.
Laurel H. Carney, Xuedong Zhang
openaire   +3 more sources

How are the Inner Hair Cells and Auditory Nerve Fibers Activated without the Mediation of the Outer Hair Cells and the Cochlear Amplifier?

Journal of Basic and Clinical Physiology and Pharmacology, 2010
The present study was designed to assess whether, in the presence of a depression of the cochlear amplifier i.e. a sensorineural hearing loss (SNHL), the inner hair cells (IHCs) require the presence of a normal endocochlear potential for transduction. An SNHL was induced by injecting salicylic acid (which binds to the motor protein prestin in the outer
Haim Sohmer, Cahtia Adelman, Jeffrey M Weinberger   +2 more
openaire   +2 more sources

The masking level difference in chinchilla auditory cortex. Effects of inner hair cell loss

Hearing Research, 2003
The purpose of the present study was to investigate responses from the unanesthetized chinchilla auditory cortex (AC) to conditions producing a masking level difference (MLD) in perceptual studies, both before and after inner hair cell (IHC) loss caused by carboplatin. Tungsten electrodes were chronically implanted in the right AC (active) and anterior
Robert Burkard, Yuqing Guo
openaire   +3 more sources

Kainic acid selectively alters auditory dendrites connected with cochlear inner hair cells

Hearing Research, 1985
Cochleas of adult guinea pigs and rats, and 6-day-old rat pups, were injected, through the round window, with 2 microliters of artificial classical Konishi perilymph containing 1 nmol kainic acid (KA). 5 min later, they were fixed, removed, and processed for electron microscopy. In all KA-treated cochleas, the injection resulted in a severe swelling of
Marc Lenoir, Rémy Pujol, Brian M. Johnstone, Michel Eybalin, Donald Robertson   +4 more
openaire   +3 more sources

The effects of the activation of the inner-hair-cell basolateral K+ channels on auditory nerve responses

Hearing Research, 2018
The basolateral membrane of the mammalian inner hair cell (IHC) expresses large voltage and Ca2+ gated outward K+ currents. To quantify how the voltage-dependent activation of the K+ channels affects the functionality of the auditory nerve innervating the IHC, this study adopts a model of mechanical-to-neural transduction in which the basolateral K ...
Pulkki, Ville, Verhulst, Sarah, Altoè, Alessandro   +3 more
openaire   +2 more sources

Vascular endothelial growth factor is required for regeneration of auditory hair cells in the avian inner ear

Hearing Research, 2020
Hair cells in the auditory organ of the vertebrate inner ear are the sensory receptors that convert acoustic stimuli into electrical signals that are conveyed along the auditory nerve to the brainstem. Hair cells are highly susceptible to ototoxic drugs, infection, and acoustic trauma, which can cause cellular degeneration.
Michael Lovett, Liangcai Wan, Mark E. Warchol, Jennifer S. Stone   +3 more
openaire   +3 more sources

Phase opposition between inner and outer hair cells and auditory sound analysis

International Journal of Audiology, 1975
Recordings of single-unit responses in the auditory nerve of normal and kanamycin-treated Mongolian gerbils indicate that inner and outer hair cells of the cochlea interact in phase opposition. After kanamycin treatment, the firing rate in some fibers is increased during the basilar membrane motion toward scala vestibuli, in others, during its motion ...
openaire   +3 more sources