Results 211 to 220 of about 50,414 (231)

Distribution of the 275 kD hair cell antigen and cell surface specialisations on auditory and vestibular hair bundles in the chicken inner ear

Journal of Comparative Neurology, 1992
AbstractThe 275 kD hair cell antigen (HCA) is a protein that is specifically associated with the apical surface of sensory hair cells in the chick inner ear. A comparative study of the vestibular and auditory organs of the inner ear, using both wholemounts and cryosections double labelled for the HCA and F‐actin, reveals that two distinct types of hair
Guy P. Richardson, Richard J. Goodyear
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An Analog VLSI Implementation of the Inner Hair Cell and Auditory Nerve Using a Dual AGC Model

IEEE Transactions on Biomedical Circuits and Systems, 2014
An analog inner hair cell and auditory nerve circuit using a dual AGC model has been implemented using 0.35 micron mixed-signal technology. A fully-differential current-mode architecture is used and the ability to correct channel mismatch is evaluated with matched layouts as well as with digital current tuning.
Howard I. Cohen, Christian Karl, Socrates Deligeorges, Allyn E. Hubbard, David S. Freedman   +4 more
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Loss of inner hair cell ribbon synapses and auditory nerve fiber regression in Cldn14 knockout mice

Hearing Research, 2020
Proper functioning of the auditory nerve is of critical importance for auditory rehabilitation by cochlear implants. Here we used the Cldn14-/- mouse to study in detail the effects of Claudin 14 loss on auditory synapses and the auditory nerve. Mutations in the tight junction protein Claudin 14 cause autosomal recessive non-syndromic hearing loss ...
J Schulze, Hans Gerd Nothwang, Maike Claußen   +2 more
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Two Modes of Auditory Hair Cell Loss following Acoustic Overstimulation in the Avian Inner Ear

ORL, 1997
To determine the type of cell death occurring and how the removal of damaged cells proceeds following overstimulation, we examined chick basilar papillae using an in situ DNA nick end labeling method and transmission electron microscopy. Two distinct modes of hair cell loss were identified.
Masahiro Takayama, Hideo Yamane, Kishiko Sunami, Takayuki Nakagawa, Shigetaro Shibata, Yoshiaki Nakai   +5 more
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Two-tone suppression in inner hair cell responses: Correlates of rate suppression in the auditory nerve

Hearing Research, 1992
Inner hair cell (IHC) recordings were made from second turn of the guinea pig cochlea where characteristic frequencies are approximately 4000 Hz. In order to compare IHC responses with rate suppression measured in the auditory nerve, suppressors were introduced that produced little or no response in the hair cell.
Peter Dallos, Mary Ann Cheatham
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Auditory and vestibular hair cell stereocilia: relationship between functionality and inner ear disease

The Journal of Laryngology & Otology, 2011
AbstractThe stereocilia of the inner ear are unique cellular structures which correlate anatomically with distinct cochlear functions, including mechanoelectrical transduction, cochlear amplification, adaptation, frequency selectivity and tuning. Their function is impaired by inner ear stressors, by various types of hereditary deafness, syndromic ...
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Inner hair cell synapse density influences auditory processing

2022
AbstractLoss of synapses between spiral ganglion neurons and inner hair cells (IHC synaptopathy), leads to an auditory neuropathy called hidden hearing loss (HHL) characterized by normal auditory thresholds but reduced amplitude of sound-evoked auditory potentials. It has been proposed that synaptopathy and HHL result in poor performance in challenging
Lingchao Ji, Beatriz C. Borges, David T. Martel, Calvin Wu, M. Charles Liberman, Susan E. Shore, Gabriel Corfas   +6 more
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Inner hair cell loss and steady-state potentials from the inferior colliculus and auditory cortex of the chinchilla

The Journal of the Acoustical Society of America, 2002
Steady-state evoked potentials were measured from unanesthetized chinchillas both before and after carboplatin-induced selective inner hair cell loss. Recordings were made from both the inferior colliculus (IC) and the auditory cortex (AC). The steady-state potential was measured in the form of the envelope following response (EFR), obtained by ...
Robert Burkard, Sally A. Arnold
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Conditional Tnfaip6-Knockout in Inner Ear Hair Cells Does not Alter Auditory Function

Neuroscience Bulletin
Noise-induced hearing loss is a worldwide public health issue that is characterized by temporary or permanent changes in hearing sensitivity. This condition is closely linked to inflammatory responses, and interventions targeting the inflammatory gene tumor necrosis factor-alpha (TNFα) are known to mitigate cochlear noise damage. TNFα-induced proteins (
Yue, Qiu, Song, Gao, Xiaoqiong, Ding, Jie, Lu, Xinya, Ji, Wenli, Hao, Siqi, Cheng, Haolinag, Du, Yajun, Gu, Chenjie, Yu, Cheng, Cheng, Xia, Gao   +11 more
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Onset and offset responses from inferior colliculus and auditory cortex to paired noisebursts: inner hair cell loss

Hearing Research, 2002
Thirteen adult chinchillas were anesthetized with ketamine/acepromazine and tungsten electrodes were placed in the right inferior colliculus (IC) and auditory cortex (AC). A reference electrode was implanted in the anterior cranium. Following a recovery period, AC and IC responses to left ear stimulation were obtained from unanesthetized animals ...
Robert Burkard, Yuqing Guo
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