Results 91 to 100 of about 37,849 (259)

The Skin Microenvironment: A Dynamic Regulator of Hair Follicle Development, Cycling and Disease

Biomolecules
As essential skin appendages, hair follicles exhibit complex developmental and regenerative processes shaped by the skin microenvironment. Imbalances in skin microenvironmental homeostasis are often accompanied by follicle miniaturization and even hair ...
Weiguo Song, Mingli Peng, Qiqi Ma, Xiaoyu Han, Chunyan Gao, Wenqi Zhang, Dongjun Liu   +6 more
doaj   +1 more source

Self‐Amplifying Redox Cycle Triggers Ferroptosis/Cuproptosis Synergy for Enhanced Bacterial Eradication

Advanced Science, EarlyView.
This study designs a targeted nanocomposite (ct@HMCF‐Dex) that responds to acidic infection microenvironments, releasing components which amplify oxidative stress. It disrupts bacterial redox balance, chelates metals to sustain lipid peroxidation, and synergistically induces cuproptosis/ferroptosis‐like death.
Zehui Xiao, Shaolong Qiu, Jiangli Cao, Jifeng Liu, Zhiyong Song, Ting Du, Xinjun Du   +6 more
wiley   +1 more source

Metabolomics reveals metabolites associated with hair follicle cycle in cashmere goats

BMC Veterinary Research
Background The hair follicle is a skin accessory organ that regulates hair development, and its activity varies on a regular basis. However, the significance of metabolites in the hair follicle cycle has long been unknown.
Shengchao Ma, Wenzhi Cao, Xiaolin Ma, Xiaofang Ye, Chongkai Qin, Bin Li, Wenna Liu, Qingwei Lu, Cuiling Wu, Xuefeng Fu   +9 more
doaj   +1 more source

The form of the hair follicle in the human scalp as an indicator of human relationships [PDF]

, 1991
The form of the hair follicle has been examined in some human isolates. There is no relationship between follicular structure and hair form, that is, similar hair forms may be the end product of different follicular structures.
Barber, L, Plomley, B
core   +2 more sources

Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers

Advanced Science, EarlyView.
This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu, Yujia Zhou, Zihan Zhang, Rong Ma, Luyi Ruan, Liqing Miao, Boxin Zhang, Huihui Ji, Tianfeng Chen, Xueqiong Zhu   +9 more
wiley   +1 more source

Mesenchymal stem cell-derived exosomes promote scalp rejuvenation through type XVII collagen regulation via the miR-21-5p/DKK2/Wnt pathway

Frontiers in Cell and Developmental Biology
BackgroundHair follicle aging is driven by COL17A1 proteolysis in hair follicle stem cells (HFSCs). Mesenchymal stem cell (MSC)-derived exosomes show promise in tissue regeneration, but their effects on COL17A1 and hair follicle aging remain unexplored ...
Shiyue Cui, Yuanyuan Huang, Duo Zeng, Jie Li, Chun Tang   +4 more
doaj   +1 more source

Jagged1 and Epidermal Growth Factor Promoted Androgen-Suppressed Mouse Hair Growth In Vitro and In Vivo

Frontiers in Pharmacology, 2020
Recent studies have reported that T-reg cells are intimately linked with hair follicles in a stage-dependent manner and play an important role in hair follicle cycling and regeneration in murine skin.
Yufeng Lin, Canying Liu, Xiaoshu Zhan, Xiaoshu Zhan, Bingyun Wang, Kui Li, Kui Li, Julang Li   +7 more
doaj   +1 more source

Androgenetic alopecia: a review [PDF]

, 2017
Purpose Androgenetic alopecia, commonly known as male pattern baldness, is the most common type of progressive hair loss disorder in men. The aim of this paper is to review recent advances in understanding the pathophysiology and molecular mechanism
Caro, Gemma, Fortuna, MARIA CATERINA, Lenzi, Andrea, Lolli, Francesca, Lombardo, Francesco, Pallotti, Francesco, Rossi, Alfredo, Sansone, Andrea   +7 more
core   +1 more source

Dual‐Network Protein Hydrogels Promote Rapid Hemostasis and Immune‐Regulated Scarless Tissue Regeneration

Advanced Science, EarlyView.
A dual‐network protein hydrogel substantially improves hemostasis and scar‐free healing.The adaptive network maintains intimate tissue contact while providing strong wet adhesion, tunable mechanics, and controlled degradation. Concurrent ROS scavenging and M2 polarization suppress fibrotic pathways, preventing scar formation.
Xiaomei Li, Guorui Zhang, Xinyue Wang, Zhongyu Liu, Ling Yang, Yuhan Bao, Min Wei, Yonglin Chen, Yanfei Ma, Wenbo Sheng, Bo Yu, Bin Li   +11 more
wiley   +1 more source

Canine recurrent flank alopecia: a synthesis of theory and practice [PDF]

, 2014
Canine recurrent flank alopecia is a non-inflammatory, non-scarring alopecia of unknown etiology and has a visually striking clinical presentation.
Daminet, Sylvie, De Cock, Hilde, Declercq, Jan, Vandenabeele, Sophie   +3 more
core   +2 more sources