Results 11 to 20 of about 56,820 (295)

Signaling Involved in Hair Follicle Morphogenesis and Development [PDF]

International Journal of Molecular Sciences, 2014
Hair follicle morphogenesis depends on Wnt, Shh, Notch, BMP and other signaling pathways interplay between epithelial and mesenchymal cells. The Wnt pathway plays an essential role during hair follicle induction, Shh is involved in morphogenesis and late stage differentiation, Notch signaling determines stem cell fate while BMP is involved in cellular ...
Rishikaysh, Pisal, Dev, Kapil, Diaz, Daniel, Qureshi, Wasay Mohiuddin Shaikh, Filip, Stanislav, Mokry, Jaroslav   +5 more
openaire   +4 more sources

Live imaging of stem cell and progeny behaviour in physiological hair-follicle regeneration [PDF]

Nature, 2012
Tissue development and regeneration depend on cell-cell interactions and signals that target stem cells and their immediate progeny. However, the cellular behaviours that lead to a properly regenerated tissue are not well understood.
A Uchugonova, Ann M. Haberman, C Lo Celso, CA Jahoda, David G. Gonzalez, E Fuchs, Elizabeth R. Deschene, FM Watt, G Cotsarelis, Giovanni Zito, H Oshima, H Ra, Ichiko Saotome, JB Wallingford, L Rubin, M Eiraku, M Petersson, M Rendl, MV Plikus, Panteleimon Rompolas, S Müller-Röver, SJ Morrison, SK Waghmare, T Tumbar, V Greco, V Greco, Valentina Greco, Y Xie, YV Zhang   +28 more
core   +3 more sources

Progress on mitochondria and hair follicle development in androgenetic alopecia: relationships and therapeutic perspectives [PDF]

Stem Cell Research & Therapy
Hair loss has long been a significant concern for many individuals. Recent studies have indicated that mitochondria play a more crucial role in hair loss than previously recognized.
Ting-ru Dong, Yu-jie Li, Shi-yu Jin, Feng-lan Yang, Ren-xue Xiong, Ye-qin Dai, Xiu-zu Song, Cui-ping Guan   +7 more
doaj   +2 more sources

Molecular Mechanisms of Hair Follicle Development. [PDF]

ScientificWorldJournal
Hair is an intricate biological structure that originates from hair follicles (HFs), which are complex mini‐organs embedded in the skin. Each HF undergoes continuous cycles of growth (anagen), regression (catagen), and rest (telogen), driven by intricate signaling pathways and interactions between epithelial and mesodermal cells. The development of HFs
Kinde MZ, Mekuria TA, Gessese AT, Mengistu BA.   +3 more
europepmc   +4 more sources

Immune niches for hair follicle development and homeostasis. [PDF]

Front Physiol
The hair follicle is a dynamic mini-organ that has specialized cycles and architectures with diverse cell types to form hairs. Previous studies for several decades have investigated morphogenesis and signaling pathways during embryonic development and adult hair cycles in both mouse and human skin.
Kiselev A, Park S.
europepmc   +4 more sources

Expression profile of long non-coding RNA in inner Mongolian cashmere goat with putative roles in hair follicles development

Frontiers in Veterinary Science, 2022
The hair follicle is a complex skin accessory organ, which determines hair growth. Long non-coding RNAs (lncRNAs) have been proven to play an important role in hair follicle development, but their specific mechanism is still unclear.
Rong Ma, Fangzheng Shang, Youjun Rong, Jianfeng Pan, Min Wang, Shuran Niu, Yunpeng Qi, Yanbo Li, Qi Lv, Zhiying Wang, Ruijun Wang, Rui Su, Zhihong Liu, Yanhong Zhao, Zhixin Wang, Jinquan Li, Jinquan Li, Jinquan Li, Yanjun Zhang   +18 more
doaj   +1 more source

Wls is expressed in the epidermis and regulates embryonic hair follicle induction in mice. [PDF]

PLoS ONE, 2012
Wnt proteins are secreted molecules that play multiple roles during hair follicle development and postnatal hair cycling. Wntless (Wls) is a cargo protein required for the secretion of various Wnt ligands.
Sixia Huang, Xuming Zhu, Yanfang Liu, Yixin Tao, Guoyin Feng, Lin He, Xizhi Guo, Gang Ma   +7 more
doaj   +1 more source

Novel recombinant R-spondin1 promotes hair regeneration by targeting the Wnt/β-catenin signaling pathway

Acta Biochimica et Biophysica Sinica, 2023
Roof plate-specific spondin 1 (R-spondin1, RSPO1) is a Wnt/β-catenin signaling pathway activator that binds with Wnt ligands to stimulate the Wnt/β-catenin signaling pathway, which is key to hair regeneration. However, it is not clear whether recombinant
Chen Yijun, Lu Zhujin, Feng Jiaxin, Chen Zefeng, Liu Zejian, Wang Xiuqi, Yan Huichao, Gao Chunqi   +7 more
doaj   +1 more source

Exploring differentially expressed genes by RNA-Seq in cashmere goat (Capra hircus) skin during hair follicle development and cycling. [PDF]

PLoS ONE, 2013
Cashmere goat (Capra hircus) hair follicle development and cycling can be divided into three stages: anagen, catagen and telogen. To elucidate the genes involved in hair follicle development and cycling in cashmere goats, transcriptome profiling of skin ...
Rongqing Geng, Chao Yuan, Yulin Chen
doaj   +1 more source

Morphogenesis, Growth Cycle and Molecular Regulation of Hair Follicles

Frontiers in Cell and Developmental Biology, 2022
As one of the main appendages of skin, hair follicles play an important role in the process of skin regeneration. Hair follicle is a tiny organ formed by the interaction between epidermis and dermis, which has complex and fine structure and periodic ...
Xiangyu Lin, Liang Zhu, Jing He
doaj   +1 more source