Results 41 to 50 of about 56,820 (295)

Disruption of Vitamin D and Calcium Signaling in Keratinocytes Predisposes to Skin Cancer. [PDF]

, 2016
1,25 dihydroxyvitamin D (1,25(OH)2D), the active metabolite of vitamin D, and calcium regulate epidermal differentiation. 1,25(OH)2D exerts its effects through the vitamin D receptor (VDR), a transcription factor in the nuclear hormone receptor family ...
Bikle, Daniel D, Jiang, Yan, Nguyen, Thai, Oda, Yuko, Tu, Chia-Ling   +4 more
core   +2 more sources

Pigment Intensity in Dogs is Associated with a Copy Number Variant Upstream of KITLG. [PDF]

, 2020
Dogs exhibit a wide variety of coat color types, and many genes have been identified that control pigment production, appearance, and distribution. Some breeds, such as the Nova Scotia Duck Tolling Retriever (NSDTR), exhibit variation in pheomelanin ...
Affolter, Verena, Bannasch, Danika, Grahn, Robert, Kallenberg, Angelica, Rebhun, Robert, Weich, Kalie, York, Daniel   +6 more
core   +2 more sources

A splice variant in KRT71 is associated with curly coat phenotype of Selkirk Rex cats. [PDF]

, 2013
One of the salient features of the domestic cat is the aesthetics of its fur. The Selkirk Rex breed is defined by an autosomal dominant woolly rexoid hair (ADWH) abnormality that is characterized by tightly curled hair shafts.
Alhaddad, Hasan, Brem, Gottfried, Filler, Serina, Gandolfi, Barbara, Joslin, Shannon EK, Khan, Razib, Lyons, Leslie A   +6 more
core   +1 more source

Hairy tale of signaling in hair follicle development and cycling [PDF]

Seminars in Cell & Developmental Biology, 2012
Hair follicles (HFs) is an appendage from the vertebrate skin epithelium, and is critical for environmental sensing, animal appearance, and body heat maintenance. HFs arise from the embryonic ectoderm and regenerate cyclically during adult life. Distinct morphological and functional stages from development through homeostasis have been extensively ...
Jayhun, Lee, Tudorita, Tumbar
openaire   +2 more sources

Jagged1 and Epidermal Growth Factor Promoted Androgen-Suppressed Mouse Hair Growth In Vitro and In Vivo

Frontiers in Pharmacology, 2020
Recent studies have reported that T-reg cells are intimately linked with hair follicles in a stage-dependent manner and play an important role in hair follicle cycling and regeneration in murine skin.
Yufeng Lin, Canying Liu, Xiaoshu Zhan, Xiaoshu Zhan, Bingyun Wang, Kui Li, Kui Li, Julang Li   +7 more
doaj   +1 more source

Biology of human hair: Know your hair to control it [PDF]

, 2011
Hair can be engineered at different levels—its structure and surface—through modification of its constituent molecules, in particular proteins, but also the hair follicle (HF) can be genetically altered, in particular with the advent of siRNA-based ...
A Dugour, A Franbourg, A Kukita, A Louvi, A Rebora, A Roddick-Lanzilotta, A Rolland, A Slominski, A Teichmann, A Vogt, A Zimek, AA Panteleyev, AE Buhl, AH Weston, AJ Craven, AJ Craven, AJ Reynolds, AM Kligman, AP McMahon, AP Wysocki, B Bhushan, B St-Jacques, BL Hogan, C Blanpain, C Bolduc, C Chiang, C Danciulescu, C Lo Celso, C Nappe, C Pierard-Franchimont, CA Baker, CA Jahoda, CJ Silva, CM Chuong, CP Zhang, CR Borges, CY Logan, DAD Parry, DJ Tobin, E Bernard, E Fuchs, E Oshimura, EK Nishimura, EK Nishimura, F Conrad, F Hueber, G Cotsarelis, G Lindner, G Taylor, G Weinmaster, GC Davies, H Clevers, H Kulessa, H Oshima, H Schell, HB Chase, HS Oh, J Cai, J Huelsken, J Lademann, J Lademann, J Zhang, JA Faucher, JA Swift, JE Plowman, JE Plowman, JH Han, JT Headington, K Foitzik, K Hashimoto, K Kobielak, K Krause, K Narhi, K Schouwey, K Shorter, K Suzuki, KA Holbrook, KK Lin, KM Cadigan, L Karlsson, L Mecklenburg, L Pille, LC Wang, LJ Wolfram, LJ Wolfram, LN Jones, LT Krebs, M Feughelman, M Ito, M Magerl, M Magerl, M Moriyama, M Nakamura, M Ohyama, M Ohyama, M Ohyama, M Philpott, M Saitoh, MA Johnstone, MA Tran, ME Balana, ME Sawaya, MH Kwack, MS Birbeck, MV Plikus, N Beek van, N Otberg, N Sato, N Yamamoto, O Mori, OS Kwon, P Redondo, PW Ingham, R Azziz, R DasGupta, R Dawber, R Kopan, R Paus, R Schmidt-Ullrich, R Schmidt-Ullrich, R Schueller, R Yi, RC Wester, RD Sinclair, RH Wilson, RJ Block, RJ Morris, RK Freinkel, S Chanda, S Claudinot, S Cochran, S Demehri, S Estrach, S Gupta, S Inui, S Iseki, S Itami, S Kondo, S Lyle, S Maretto, S Muller-Rover, S Reddy, S Vauclair, SD O’Connor, SE Millar, SJ Du, SL Mansberger, STA Regismond, T Andl, T Hibino, T Passeron, T Reya, T Sato, T Tumbar, TA Mitsiadis, TA Mitsiadis, TA Smith, TW Fischer, U Blume-Peytavi, U Gat, VA Botchkarev, VA Botchkarev, VA Botchkarev, VA Randall, VA Randall, VA Randall, VA Randall, VM Meidan, Y Ando, Y Asada, Y Barrandon, Y Pan, Y Ramot, YV Zhang   +173 more
core   +1 more source

Notch Signaling and the Developing Hair Follicle [PDF]

, 2012
Notch function in the hair follicle has been mainly studied by use of transgenic mice carrying either loss or gain of function mutations in various members of the pathway. These studies revealed that whereas embryonic development of the hair follicle can be achieved without Notch, its postnatal development requires an intact Notch signaling in the hair
openaire   +4 more sources

Bioengineering of Hair Follicle-like Structure for Validation of Hair Growth Promoting Compounds

Bioengineering, 2022
We aimed to establish screening and efficacy test techniques for use in the development of hair-promoting agents. To this end, we used the dermal papilla cell (DPc)-derived immortalized cell line (SV40T-hTERT DPc) and neonatal foreskin-derived ...
Hyun Woo Joo, Min Kyu Kim, Soon Sun Bak, Young Kwan Sung   +3 more
doaj   +1 more source

Hair follicle regional specificity in different parts of bay Mongolian horse by histology and transcriptional profiling

BMC Genomics, 2020
Background Different morphological structures of hairs having properties like defense and camouflage help animals survive in the wild environment.
Ruoyang Zhao, Wu Yihan, Yiping Zhao, Bei Li, Haige Han, Togtokh Mongke, Tugeqin Bao, Wenxing Wang, Manglai Dugarjaviin, Dongyi Bai   +9 more
doaj   +1 more source

Reconstitution of Hair Follicle Development In Vivo: Determination of Follicle Formation, Hair Growth, and Hair Quality by Dermal Cells

Journal of Investigative Dermatology, 1993
Combinations of cultured and uncultured epidermal and dermal cell preparations from newborn and perinatal mice were grafted onto the backs of athymic nude mouse hosts to elucidate the cellular requirements for skin appendage formation. All epidermal populations studied, including a total epidermal keratinocyte preparation from trypsin-split skin ...
Weinberg, Wendy C., Goodman, Linda V., George, Carmen, Morgan, David L., Ledbetter, Steve, Yuspa, Stuart H., Lichti, Ulrike   +6 more
openaire   +2 more sources