Results 51 to 60 of about 56,820 (295)

Cutaneous Retinoic Acid Levels Determine Hair Follicle Development and Downgrowth [PDF]

Journal of Biological Chemistry, 2012
Retinoic acid (RA) is essential during embryogenesis and for tissue homeostasis, whereas excess RA is well known as a teratogen. In humans, excess RA is associated with hair loss. In the present study, we demonstrate that specific levels of RA, regulated by Cyp26b1, one of the RA-degrading enzymes, are required for hair follicle (hf) morphogenesis ...
Junko, Okano, Clara, Levy, Ulrike, Lichti, Hong-Wei, Sun, Stuart H, Yuspa, Yasuo, Sakai, Maria I, Morasso   +6 more
openaire   +2 more sources

Identification of human papillomavirus DNA in cutaneous lesions of Cowden syndrome [PDF]

, 2003
Background: Cowden syndrome (CS) or multiple hamartoma syndrome is a cancer-associated genodermatosis inherited in an autosomal dominant pattern. One of the diagnostic criteria is facial papules which are felt to be trichilemmomas, benign hair follicle ...
Burgdorf, Walter H. C., Itin, Peter H., Lautenschlager, Stephan, Rohwedder, A., Schaller, Jörg   +4 more
core   +1 more source

Hoxa4 expression in developing mouse hair follicles and skin

Mechanisms of Development, 2000
We have examined the expression of the Hoxa4 gene in embryonic vibrissae and developing and cycling postnatal pelage hair follicles by digoxigenin-based in situ hybridization. Hoxa4 expression is first seen in E13.5 vibrissae throughout the follicle placode.
Packer, Alan I, Jane-wit, Daniel, McLean, Leon, Panteleyev, Andrei A, Christiano, Angela M, Wolgemuth, Debra J   +5 more
openaire   +2 more sources

Ginsenoside CK inhibits androgenetic alopecia by regulating Wnt/β‐catenin and p53 signaling pathways in AGA mice

Food Frontiers, 2023
Androgenetic alopecia (AGA) is one of the most common chronic skin diseases caused by the destruction of androgens in the body. It is caused by the excessive deposition of dihydrotestosterone around the hair follicle, resulting in hair follicle atrophy ...
Chao Fang, Haixia Yang, Chenhui Zhu, Daidi Fan, Jianjun Deng   +4 more
doaj   +1 more source

Expression of Frizzled Genes in Developing and Postnatal Hair Follicles [PDF]

Journal of Investigative Dermatology, 2004
Embryonic hair follicle development and postnatal hair growth rely on intercellular communication within the epithelium and between epithelial and mesenchymal cells. Several members of the WNT family of paracrine intercellular signaling molecules are expressed in specific subsets of cells in developing and mature mouse hair follicles, suggesting them ...
Reddy, Seshamma T., Andl, Thomas, Lu, Min-Min, Morrisey, Edward E., Millar, Sarah E.   +4 more
openaire   +2 more sources

Inflammatory mediator TAK1 regulates hair follicle morphogenesis and anagen induction shown by using keratinocyte-specific TAK1-deficient mice.

PLoS ONE, 2010
Transforming growth factor-beta-activated kinase 1 (TAK1) is a member of the NF-kappaB pathway and regulates inflammatory responses. We previously showed that TAK1 also regulates keratinocyte growth, differentiation, and apoptosis. However, it is unknown
Koji Sayama, Kentaro Kajiya, Koji Sugawara, Shintaro Sato, Satoshi Hirakawa, Yuji Shirakata, Yasushi Hanakawa, Xiuju Dai, Yumiko Ishimatsu-Tsuji, Daniel Metzger, Pierre Chambon, Shizuo Akira, Ralf Paus, Jiro Kishimoto, Koji Hashimoto   +14 more
doaj   +1 more source

The development of hair follicles and nail

Developmental Biology
The hair follicle and nail unit develop and regenerate through epithelial-mesenchymal interactions. Here, we review some of the key signals and molecular interactions that regulate mammalian hair follicle and nail formation during embryonic development and how these interactions are reutilized to promote their regeneration during adult homeostasis and ...
Soung-Hoon Lee, Sarah Platt, Chae Ho Lim, Mayumi Ito, Peggy Myung   +4 more
openaire   +2 more sources

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Analysis of lncRNAs Expression Profiles in Hair Follicle of Hu Sheep Lambskin

Animals, 2020
Lambskin of the Hu sheep exhibits high economic value due to its water-wave pattern. Wool curvature is the key factor of the pattern types and quality of lambskin, and it is formed by the interaction between dermal papilla cells and hair matrix cells in ...
Xiaoyang Lv, Weihao Chen, Wei Sun, Zahid Hussain, Shanhe Wang, Jinyu Wang   +5 more
doaj   +1 more source

Self-organizing & stochastic behaviors during the regeneration of hair stem cells [PDF]

, 2011
Stem cells cycle through active and quiescent states. Large populations of stem cells in an organ may cycle randomly or in a coordinated manner. Although stem cell cycling within single hair follicles has been studied, less is known about regenerative ...
Andl, T, Baker, RE, Chen, CC, Chuong, CM, de la Cruz, D, Fare, C, Maini, Philip, Millar, SE, Plikus, MV, Widelitz, R   +9 more
core   +1 more source